Receptors, Dopamine D2
"Receptors, Dopamine D2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subfamily of G-PROTEIN-COUPLED RECEPTORS that bind the neurotransmitter DOPAMINE and modulate its effects. D2-class receptor genes contain INTRONS, and the receptors inhibit ADENYLATE CYCLASE.
Descriptor ID |
D017448
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MeSH Number(s) |
D12.776.543.750.070.300.400.500 D12.776.543.750.100.150.400.500 D12.776.543.750.720.300.300.400.500
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Concept/Terms |
Receptors, Dopamine D2- Receptors, Dopamine D2
- Dopamine-D2 Receptor
- Dopamine D2 Receptor
- Receptor, Dopamine-D2
- Dopamine D2 Receptors
- D2 Receptors, Dopamine
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Below are MeSH descriptors whose meaning is more general than "Receptors, Dopamine D2".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Biogenic Amine [D12.776.543.750.070]
- Receptors, Catecholamine [D12.776.543.750.070.300]
- Receptors, Dopamine [D12.776.543.750.070.300.400]
- Receptors, Dopamine D2 [D12.776.543.750.070.300.400.500]
- Receptors, G-Protein-Coupled [D12.776.543.750.100]
- Receptors, Catecholamine [D12.776.543.750.100.150]
- Receptors, Dopamine [D12.776.543.750.100.150.400]
- Receptors, Dopamine D2 [D12.776.543.750.100.150.400.500]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Biogenic Amine [D12.776.543.750.720.300]
- Receptors, Catecholamine [D12.776.543.750.720.300.300]
- Receptors, Dopamine [D12.776.543.750.720.300.300.400]
- Receptors, Dopamine D2 [D12.776.543.750.720.300.300.400.500]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Dopamine D2".
This graph shows the total number of publications written about "Receptors, Dopamine D2" by people in this website by year, and whether "Receptors, Dopamine D2" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1986 | 0 | 2 | 2 | 1987 | 0 | 2 | 2 | 1990 | 0 | 1 | 1 | 1993 | 1 | 0 | 1 | 1994 | 3 | 1 | 4 | 1995 | 1 | 0 | 1 | 1996 | 3 | 0 | 3 | 1997 | 1 | 1 | 2 | 1998 | 1 | 0 | 1 | 1999 | 1 | 0 | 1 | 2000 | 1 | 0 | 1 | 2001 | 1 | 1 | 2 | 2003 | 0 | 2 | 2 | 2004 | 2 | 1 | 3 | 2005 | 1 | 2 | 3 | 2006 | 2 | 1 | 3 | 2008 | 1 | 0 | 1 | 2009 | 4 | 0 | 4 | 2011 | 1 | 1 | 2 | 2012 | 1 | 2 | 3 | 2014 | 1 | 0 | 1 | 2015 | 4 | 0 | 4 | 2016 | 3 | 1 | 4 | 2017 | 1 | 0 | 1 | 2018 | 1 | 0 | 1 | 2019 | 2 | 0 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Receptors, Dopamine D2" by people in Profiles.
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Mourra D, Gnazzo F, Cobos S, Beeler JA. Striatal Dopamine D2 Receptors Regulate Cost Sensitivity and Behavioral Thrift. Neuroscience. 2020 01 15; 425:134-145.
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Caragher SP, Shireman JM, Huang M, Miska J, Atashi F, Baisiwala S, Hong Park C, Saathoff MR, Warnke L, Xiao T, Lesniak MS, James CD, Meltzer H, Tryba AK, Ahmed AU. Activation of Dopamine Receptor 2 Prompts Transcriptomic and Metabolic Plasticity in Glioblastoma. J Neurosci. 2019 03 13; 39(11):1982-1993.
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Prabhu VV, Madhukar NS, Gilvary C, Kline CLB, Oster S, El-Deiry WS, Elemento O, Doherty F, VanEngelenburg A, Durrant J, Tarapore RS, Deacon S, Charter N, Jung J, Park DM, Gilbert MR, Rusert J, Wechsler-Reya R, Arrillaga-Romany I, Batchelor TT, Wen PY, Oster W, Allen JE. Dopamine Receptor D5 is a Modulator of Tumor Response to Dopamine Receptor D2 Antagonism. Clin Cancer Res. 2019 04 01; 25(7):2305-2313.
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Steidl S, O'Sullivan S, Pilat D, Bubula N, Brown J, Vezina P. Operant responding for optogenetic excitation of LDTg inputs to the VTA requires D1 and D2 dopamine receptor activation in the NAcc. Behav Brain Res. 2017 08 30; 333:161-170.
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Koranda JL, Krok AC, Xu J, Contractor A, McGehee DS, Beeler JA, Zhuang X. Chronic Nicotine Mitigates Aberrant Inhibitory Motor Learning Induced by Motor Experience under Dopamine Deficiency. J Neurosci. 2016 05 11; 36(19):5228-40.
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Salinas AG, Davis MI, Lovinger DM, Mateo Y. Dopamine dynamics and cocaine sensitivity differ between striosome and matrix compartments of the striatum. Neuropharmacology. 2016 09; 108:275-83.
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Sung YM, Wilkins AD, Rodriguez GJ, Wensel TG, Lichtarge O. Intramolecular allosteric communication in dopamine D2 receptor revealed by evolutionary amino acid covariation. Proc Natl Acad Sci U S A. 2016 Mar 29; 113(13):3539-44.
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Siciliano CA, Calipari ES, Yorgason JT, Lovinger DM, Mateo Y, Jimenez VA, Helms CM, Grant KA, Jones SR. Increased presynaptic regulation of dopamine neurotransmission in the nucleus accumbens core following chronic ethanol self-administration in female macaques. Psychopharmacology (Berl). 2016 Apr; 233(8):1435-43.
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Siciliano CA, Calipari ES, Yorgason JT, Mateo Y, Helms CM, Lovinger DM, Grant KA, Jones SR. Chronic ethanol self-administration in macaques shifts dopamine feedback inhibition to predominantly D2 receptors in nucleus accumbens core. Drug Alcohol Depend. 2016 Jan 01; 158:159-63.
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Cade BE, Gottlieb DJ, Lauderdale DS, Bennett DA, Buchman AS, Buxbaum SG, De Jager PL, Evans DS, Fülöp T, Gharib SA, Johnson WC, Kim H, Larkin EK, Lee SK, Lim AS, Punjabi NM, Shin C, Stone KL, Tranah GJ, Weng J, Yaffe K, Zee PC, Patel SR, Zhu X, Redline S, Saxena R. Common variants in DRD2 are associated with sleep duration: the CARe consortium. Hum Mol Genet. 2016 Jan 01; 25(1):167-79.
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