"Okadaic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A specific inhibitor of phosphoserine/threonine protein phosphatase 1 and 2a. It is also a potent tumor promoter. (Thromb Res 1992;67(4):345-54 & Cancer Res 1993;53(2):239-41)
- Okadaic Acid
- Acid, Okadaic
- Ocadaic Acid
- Acid, Ocadaic
Below are MeSH descriptors whose meaning is more general than "Okadaic Acid".
Below are MeSH descriptors whose meaning is more specific than "Okadaic Acid".
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Below are the most recent publications written about "Okadaic Acid" by people in Profiles.
N-CoR pathway targeting induces glioblastoma derived cancer stem cell differentiation. Cell Cycle. 2007 Feb 15; 6(4):467-70.
Phosphatase 2A is involved in endothelial cell microtubule remodeling and barrier regulation. J Cell Biochem. 2004 Jun 01; 92(3):534-46.
Extracellular signal-regulated kinase 1/2-mediated phosphorylation of cytosolic phospholipase A2 is essential for human eosinophil adhesion to fibronectin. J Immunol. 2001 Mar 01; 166(5):3515-21.
Augmentation of calcium current by hypoxia in carotid body glomus cells. Adv Exp Med Biol. 2000; 475:589-99.
A unique Na+/H+ exchanger, analogous to NHE1, in the chicken embryonic fibroblast. Am J Physiol. 1999 03; 276(3):R838-46.
Evidence for a dithiol-activated signaling pathway in natural killer cell avidity regulation of leukocyte function antigen-1: structural requirements and relationship to phorbol ester- and CD16-triggered pathways. Blood. 1995 Sep 15; 86(6):2288-301.
1,25-Dihydroxyvitamin D3 stimulates the phosphorylation of two acidic membrane proteins of 42,000 and 48,000 daltons in rat colonocytes: an effect modulated by vitamin D status. J Cell Physiol. 1995 Feb; 162(2):172-80.
Nitric oxide and cGMP cause vasorelaxation by activation of a charybdotoxin-sensitive K channel by cGMP-dependent protein kinase. Proc Natl Acad Sci U S A. 1994 Aug 02; 91(16):7583-7.
Structurally different members of the okadaic acid class selectively inhibit protein serine/threonine but not tyrosine phosphatase activity. Toxicon. 1992 Aug; 30(8):873-8.