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James Dolezal

InstitutionUniversity of Chicago
DepartmentMedicine-Hematology and Oncology
AddressChicago IL 60637
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Applebaum M, Ramesh S, Dyer E, Pomaville M, Doytcheva K, Dolezal J, Kochanny S, Terhaar R, Mehrhoff C, Patel K, Brewer J, Kusswurm B, Naranjo A, Shimada H, Sokol E, Cohn S, George R, Pearson A. Artificial intelligence-based morphologic classification and molecular characterization of neuroblastic tumors from digital histopathology. Res Sq. 2024 Jun 04. PMID: 38883758; PMCID: PMC11177984.
    2. Dolezal JM, Kochanny S, Dyer E, Ramesh S, Srisuwananukorn A, Sacco M, Howard FM, Li A, Mohan P, Pearson AT. Slideflow: deep learning for digital histopathology with real-time whole-slide visualization. BMC Bioinformatics. 2024 Mar 27; 25(1):134. PMID: 38539070; PMCID: PMC10967068.
      Citations: 1     Fields:    
    3. Hines JB, Cameron RB, Esposito A, Kim L, Porcu L, Nuccio A, Viscardi G, Ferrara R, Veronesi G, Forde PM, Taube J, Vokes E, Bestvina CM, Dolezal JM, Sacco M, Monteforte M, Cascone T, Garassino MC, Torri V. Evaluation of Major Pathologic Response and Pathologic Complete Response as Surrogate End Points for Survival in Randomized Controlled Trials of Neoadjuvant Immune Checkpoint Blockade in Resectable in NSCLC. J Thorac Oncol. 2024 Jul; 19(7):1108-1116. PMID: 38461929.
      Citations: 1     Fields:    Translation:Humans
    4. Cameron RB, Hines JB, Torri V, Porcu L, Donington J, Bestvina CM, Vokes E, Dolezal JM, Esposito A, Garassino MC. What is the ideal endpoint in early-stage immunotherapy neoadjuvant trials in lung cancer? Ther Adv Med Oncol. 2023; 15:17588359231198446. PMID: 37720499; PMCID: PMC10504845.
    5. Lo Russo G, Dolezal J, Beninato T, Agnelli L, Triulzi T, Fabbri A, Lorenzini D, Ferrara R, Brambilla M, Occhipinti M, Mazzeo L, Provenzano L, Spagnoletti A, Viscardi G, Sgambelluri F, Brich S, Miskovic V, Pedrocchi ALG, Trovo' F, Manglaviti S, Giani C, Ambrosini P, Leporati R, Franza A, McCulloch J, Torelli T, Anichini A, Mortarini R, Trinchieri G, Pruneri G, Torri V, De Braud F, Proto C, Ganzinelli M, Garassino MC, Prelaj A. PEOPLE (NTC03447678), a phase II trial to test pembrolizumab as first-line treatment in patients with advanced NSCLC with PD-L1 <50%: a multiomics analysis. J Immunother Cancer. 2023 06; 11(6). PMID: 37286305; PMCID: PMC10254948.
      Citations: 3     Fields:    Translation:HumansCTClinical Trials
    6. Dolezal JM, Wolk R, Hieromnimon HM, Howard FM, Srisuwananukorn A, Karpeyev D, Ramesh S, Kochanny S, Kwon JW, Agni M, Simon RC, Desai C, Kherallah R, Nguyen TD, Schulte JJ, Cole K, Khramtsova G, Garassino MC, Husain AN, Li H, Grossman R, Cipriani NA, Pearson AT. Deep learning generates synthetic cancer histology for explainability and education. NPJ Precis Oncol. 2023 May 29; 7(1):49. PMID: 37248379; PMCID: PMC10227067.
      Citations: 3     
    7. Howard FM, Dolezal J, Kochanny S, Khramtsova G, Vickery J, Srisuwananukorn A, Woodard A, Chen N, Nanda R, Perou CM, Olopade OI, Huo D, Pearson AT. Integration of clinical features and deep learning on pathology for the prediction of breast cancer recurrence assays and risk of recurrence. NPJ Breast Cancer. 2023 Apr 14; 9(1):25. PMID: 37059742; PMCID: PMC10104799.
      Citations: 8     
    8. Khurram SA, Kowalski LP, Dos Santos HT, Warnakulasuriya S, Dolezal J, Pearson AT, de Souza LL, Fonseca FP, Ara├║jo ALD, Lopes MA, Vargas PA, Santos-Silva AR. Machine learning for detection and classification of oral potentially malignant disorders: A conceptual review. J Oral Pathol Med. 2023 Mar; 52(3):197-205. PMID: 36792771.
      Citations: 2     Fields:    Translation:Humans
    9. Partin A, Brettin T, Zhu Y, Dolezal JM, Kochanny S, Pearson AT, Shukla M, Evrard YA, Doroshow JH, Stevens RL. Data augmentation and multimodal learning for predicting drug response in patient-derived xenografts from gene expressions and histology images. Front Med (Lausanne). 2023; 10:1058919. PMID: 36960342; PMCID: PMC10027779.
      Citations: 2     
    10. Prelaj A, Ganzinelli M, Trovo' F, Roisman LC, Pedrocchi ALG, Kosta S, Restelli M, Ambrosini E, Broggini M, Pravettoni G, Monzani D, Nuara A, Amat R, Spathas N, Willis M, Pearson A, Dolezal J, Mazzeo L, Sangaletti S, Correa AM, Aguaron A, Popa C, Raimondi G, Triulzi T, Steurer S, Lo Russo G, Linardou H, Peled N, Felip E, Garassino MC, Watermann I, Reck M. The EU-funded I3LUNG Project: Integrative Science, Intelligent Data Platform for Individualized LUNG Cancer Care With Immunotherapy. Clin Lung Cancer. 2023 06; 24(4):381-387. PMID: 36959048.
      Citations: 2     Fields:    Translation:Humans
    11. Ramesh S, Dolezal JM, Pearson AT. Applications of Deep Learning in Endocrine Neoplasms. Surg Pathol Clin. 2023 Mar; 16(1):167-176. PMID: 36739164.
      Citations: 1     Fields:    Translation:Humans
    12. Dolezal JM, Srisuwananukorn A, Karpeyev D, Ramesh S, Kochanny S, Cody B, Mansfield AS, Rakshit S, Bansal R, Bois MC, Bungum AO, Schulte JJ, Vokes EE, Garassino MC, Husain AN, Pearson AT. Uncertainty-informed deep learning models enable high-confidence predictions for digital histopathology. Nat Commun. 2022 11 02; 13(1):6572. PMID: 36323656; PMCID: PMC9630455.
      Citations: 10     Fields:    Translation:Humans
    13. Jackson LE, Kulkarni S, Wang H, Lu J, Dolezal JM, Bharathi SS, Ranganathan S, Patel MS, Deshpande R, Alencastro F, Wendell SG, Goetzman ES, Duncan AW, Prochownik EV. Correction: Genetic Dissociation of Glycolysis and the TCA Cycle Affects Neither Normal nor Neoplastic Proliferation. Cancer Res. 2022 Mar 01; 82(5):944. PMID: 35247896.
      Citations:    Fields:    
    14. Dolezal JM, Rosenberg AJ. Induction Chemotherapy in Low-Risk HPV+ Oropharyngeal Cancer. Curr Treat Options Oncol. 2022 01; 23(1):54-67. PMID: 35171457; PMCID: PMC9619415.
      Citations:    Fields:    Translation:HumansCells
    15. Howard FM, Dolezal J, Kochanny S, Schulte J, Chen H, Heij L, Huo D, Nanda R, Olopade OI, Kather JN, Cipriani N, Grossman RL, Pearson AT. The impact of site-specific digital histology signatures on deep learning model accuracy and bias. Nat Commun. 2021 07 20; 12(1):4423. PMID: 34285218; PMCID: PMC8292530.
      Citations: 68     Fields:    Translation:Humans
    16. Dolezal JM, Trzcinska A, Liao CY, Kochanny S, Blair E, Agrawal N, Keutgen XM, Angelos P, Cipriani NA, Pearson AT. Deep learning prediction of BRAF-RAS gene expression signature identifies noninvasive follicular thyroid neoplasms with papillary-like nuclear features. Mod Pathol. 2021 05; 34(5):862-874. PMID: 33299111; PMCID: PMC8064913.
      Citations: 20     Fields:    Translation:HumansCells
    17. Wang H, Lu J, Dolezal J, Kulkarni S, Zhang W, Chen A, Gorka J, Mandel JA, Prochownik EV. Inhibition of hepatocellular carcinoma by metabolic normalization. PLoS One. 2019; 14(6):e0218186. PMID: 31242205; PMCID: PMC6594671.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    18. Wang H, Dolezal JM, Kulkarni S, Lu J, Mandel J, Jackson LE, Alencastro F, Duncan AW, Prochownik EV. Myc and ChREBP transcription factors cooperatively regulate normal and neoplastic hepatocyte proliferation in mice. J Biol Chem. 2018 09 21; 293(38):14740-14757. PMID: 30087120; PMCID: PMC6153302.
      Citations: 22     Fields:    Translation:AnimalsCells
    19. Dolezal JM, Dash AP, Prochownik EV. Diagnostic and prognostic implications of ribosomal protein transcript expression patterns in human cancers. BMC Cancer. 2018 03 12; 18(1):275. PMID: 29530001; PMCID: PMC5848553.
      Citations: 46     Fields:    Translation:Humans
    20. Jackson LE, Kulkarni S, Wang H, Lu J, Dolezal JM, Bharathi SS, Ranganathan S, Patel MS, Deshpande R, Alencastro F, Wendell SG, Goetzman ES, Duncan AW, Prochownik EV. Genetic Dissociation of Glycolysis and the TCA Cycle Affects Neither Normal nor Neoplastic Proliferation. Cancer Res. 2017 11 01; 77(21):5795-5807. PMID: 28883002; PMCID: PMC5668145.
      Citations: 14     Fields:    Translation:AnimalsCells
    21. Kulkarni S, Dolezal JM, Wang H, Jackson L, Lu J, Frodey BP, Dosunmu-Ogunbi A, Li Y, Fromherz M, Kang A, Santana-Santos L, Benos PV, Prochownik EV. Ribosomopathy-like properties of murine and human cancers. PLoS One. 2017; 12(8):e0182705. PMID: 28820908; PMCID: PMC5562309.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    22. Dolezal JM, Wang H, Kulkarni S, Jackson L, Lu J, Ranganathan S, Goetzman ES, Bharathi SS, Beezhold K, Byersdorfer CA, Prochownik EV. Sequential adaptive changes in a c-Myc-driven model of hepatocellular carcinoma. J Biol Chem. 2017 06 16; 292(24):10068-10086. PMID: 28432125; PMCID: PMC5473214.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    23. Wang H, Lu J, Edmunds LR, Kulkarni S, Dolezal J, Tao J, Ranganathan S, Jackson L, Fromherz M, Beer-Stolz D, Uppala R, Bharathi S, Monga SP, Goetzman ES, Prochownik EV. Coordinated Activities of Multiple Myc-dependent and Myc-independent Biosynthetic Pathways in Hepatoblastoma. J Biol Chem. 2016 Dec 16; 291(51):26241-26251. PMID: 27738108; PMCID: PMC5159488.
      Citations: 38     Fields:    Translation:Animals
    24. Edmunds LR, Otero PA, Sharma L, D'Souza S, Dolezal JM, David S, Lu J, Lamm L, Basantani M, Zhang P, Sipula IJ, Li L, Zeng X, Ding Y, Ding F, Beck ME, Vockley J, Monga SP, Kershaw EE, O'Doherty RM, Kratz LE, Yates NA, Goetzman EP, Scott D, Duncan AW, Prochownik EV. Abnormal lipid processing but normal long-term repopulation potential of myc-/- hepatocytes. Oncotarget. 2016 May 24; 7(21):30379-95. PMID: 27105497; PMCID: PMC5058687.
      Citations: 25     Fields:    Translation:AnimalsCells
    25. Edmunds LR, Sharma L, Wang H, Kang A, d'Souza S, Lu J, McLaughlin M, Dolezal JM, Gao X, Weintraub ST, Ding Y, Zeng X, Yates N, Prochownik EV. c-Myc and AMPK Control Cellular Energy Levels by Cooperatively Regulating Mitochondrial Structure and Function. PLoS One. 2015; 10(7):e0134049. PMID: 26230505; PMCID: PMC4521957.
      Citations: 18     Fields:    Translation:AnimalsCells
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