"Protein Isoforms" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Different forms of a protein that may be produced from different GENES, or from the same gene by ALTERNATIVE SPLICING.
| Descriptor ID |
D020033
|
| MeSH Number(s) |
D12.776.800
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Protein Isoforms".
Below are MeSH descriptors whose meaning is more specific than "Protein Isoforms".
This graph shows the total number of publications written about "Protein Isoforms" by people in this website by year, and whether "Protein Isoforms" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 5 | 5 |
| 2000 | 1 | 16 | 17 |
| 2001 | 1 | 5 | 6 |
| 2002 | 1 | 12 | 13 |
| 2003 | 1 | 9 | 10 |
| 2004 | 0 | 17 | 17 |
| 2005 | 1 | 13 | 14 |
| 2006 | 1 | 9 | 10 |
| 2007 | 1 | 9 | 10 |
| 2008 | 4 | 10 | 14 |
| 2009 | 2 | 8 | 10 |
| 2010 | 0 | 6 | 6 |
| 2011 | 2 | 9 | 11 |
| 2012 | 0 | 5 | 5 |
| 2013 | 1 | 5 | 6 |
| 2014 | 1 | 7 | 8 |
| 2015 | 1 | 3 | 4 |
| 2016 | 3 | 5 | 8 |
| 2017 | 2 | 8 | 10 |
| 2018 | 1 | 4 | 5 |
| 2019 | 2 | 5 | 7 |
| 2020 | 1 | 3 | 4 |
| 2021 | 0 | 2 | 2 |
| 2022 | 0 | 3 | 3 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Protein Isoforms" by people in Profiles.
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Isoform- and ligand-specific modulation of the adhesion GPCR ADGRL3/Latrophilin3 by a synthetic binder. Nat Commun. 2023 02 06; 14(1):635.
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Activation of targetable inflammatory immune signaling is seen in myelodysplastic syndromes with SF3B1 mutations. Elife. 2022 08 30; 11.
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Inhibiting pyruvate kinase muscle isoform 2 regresses group 2 pulmonary hypertension induced by supra-coronary aortic banding. Acta Physiol (Oxf). 2022 02; 234(2):e13764.
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Genomic studies controvert the existence of the CUX1 p75 isoform. Sci Rep. 2022 01 07; 12(1):151.
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Vascular Stiffening Mediated by Rho-Associated Coiled-Coil Containing Kinase Isoforms. J Am Heart Assoc. 2021 10 19; 10(20):e022568.
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Neutrophil elastase selectively kills cancer cells and attenuates tumorigenesis. Cell. 2021 06 10; 184(12):3163-3177.e21.
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Lifelong Reduction in LDL (Low-Density Lipoprotein) Cholesterol due to a Gain-of-Function Mutation in LDLR. Circ Genom Precis Med. 2021 02; 14(1):e003029.
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A context-dependent bifurcation in the Pointed transcriptional effector network contributes specificity and robustness to retinal cell fate acquisition. PLoS Genet. 2020 11; 16(11):e1009216.
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A splice acceptor variant in HLA-DRA affects the conformation and cellular localization of the class II DR alpha-chain. Immunology. 2021 02; 162(2):194-207.
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Alternative transcripts in variant interpretation: the potential for missed diagnoses and misdiagnoses. Genet Med. 2020 07; 22(7):1269-1275.