 Protein Isoforms
"Protein Isoforms" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Different forms of a protein that may be produced from different GENES, or from the same gene by ALTERNATIVE SPLICING.
| Descriptor ID |
D020033
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| MeSH Number(s) |
D12.776.800
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Protein Isoforms".
Below are MeSH descriptors whose meaning is more specific than "Protein Isoforms".
This graph shows the total number of publications written about "Protein Isoforms" by people in this website by year, and whether "Protein Isoforms" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 5 | 5 | | 2000 | 1 | 17 | 18 | | 2001 | 1 | 5 | 6 | | 2002 | 1 | 13 | 14 | | 2003 | 1 | 9 | 10 | | 2004 | 0 | 19 | 19 | | 2005 | 1 | 13 | 14 | | 2006 | 1 | 10 | 11 | | 2007 | 1 | 9 | 10 | | 2008 | 4 | 13 | 17 | | 2009 | 2 | 8 | 10 | | 2010 | 0 | 7 | 7 | | 2011 | 3 | 9 | 12 | | 2012 | 0 | 5 | 5 | | 2013 | 1 | 5 | 6 | | 2014 | 1 | 7 | 8 | | 2015 | 1 | 3 | 4 | | 2016 | 3 | 6 | 9 | | 2017 | 2 | 8 | 10 | | 2018 | 1 | 4 | 5 | | 2019 | 2 | 5 | 7 | | 2020 | 0 | 2 | 2 |
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Below are the most recent publications written about "Protein Isoforms" by people in Profiles.
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Wu C, Boisclair Lachance JF, Ludwig MZ, Rebay I. A context-dependent bifurcation in the Pointed transcriptional effector network contributes specificity and robustness to retinal cell fate acquisition. PLoS Genet. 2020 11; 16(11):e1009216.
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Schoch K, Tan QK, Stong N, Deak KL, McConkie-Rosell A, McDonald MT. Alternative transcripts in variant interpretation: the potential for missed diagnoses and misdiagnoses. Genet Med. 2020 07; 22(7):1269-1275.
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Maiole F, Tedeschi G, Candiani S, Maragliano L, Benfenati F, Zullo L. Synapsins are expressed at neuronal and non-neuronal locations in Octopus vulgaris. Sci Rep. 2019 10 28; 9(1):15430.
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Yoon Y, Klomp J, Martin-Martin I, Criscione F, Calvo E, Ribeiro J, Schmidt-Ott U. Embryo polarity in moth flies and mosquitoes relies on distinct old genes with localized transcript isoforms. Elife. 2019 10 08; 8.
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Sulakhe D, D'Souza M, Wang S, Balasubramanian S, Athri P, Xie B, Canzar S, Agam G, Gilliam TC, Maltsev N. Exploring the functional impact of alternative splicing on human protein isoforms using available annotation sources. Brief Bioinform. 2019 09 27; 20(5):1754-1768.
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Armstrong AJ, Halabi S, Luo J, Nanus DM, Giannakakou P, Szmulewitz RZ, Danila DC, Healy P, Anand M, Rothwell CJ, Rasmussen J, Thornburg B, Berry WR, Wilder RS, Lu C, Chen Y, Silberstein JL, Kemeny G, Galletti G, Somarelli JA, Gupta S, Gregory SG, Scher HI, Dittamore R, Tagawa ST, Antonarakis ES, George DJ. Prospective Multicenter Validation of Androgen Receptor Splice Variant 7 and Hormone Therapy Resistance in High-Risk Castration-Resistant Prostate Cancer: The PROPHECY Study. J Clin Oncol. 2019 05 01; 37(13):1120-1129.
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Prakash P, Hancock JF, Gorfe AA. Three distinct regions of cRaf kinase domain interact with membrane. Sci Rep. 2019 02 14; 9(1):2057.
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Singhal SS, Salgia R, Singhal S, Horne D, Awasthi S. RLIP: An existential requirement for breast carcinogenesis. Biochim Biophys Acta Rev Cancer. 2019 04; 1871(2):281-288.
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Monteiro FP, Curry CJ, Hevner R, Elliott S, Fisher JH, Turocy J, Dobyns WB, Costa LA, Freitas E, Kitajima JP, Kok F. Biallelic loss of function variants in ATP1A2 cause hydrops fetalis, microcephaly, arthrogryposis and extensive cortical malformations. Eur J Med Genet. 2020 Jan; 63(1):103624.
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Smigiel R, Sherman DL, Rydzanicz M, Walczak A, Mikolajkow D, Krolak-Olejnik B, Kosinska J, Gasperowicz P, Biernacka A, Stawinski P, Marciniak M, Andrzejewski W, Boczar M, Krajewski P, Sasiadek MM, Brophy PJ, Ploski R. Homozygous mutation in the Neurofascin gene affecting the glial isoform of Neurofascin causes severe neurodevelopment disorder with hypotonia, amimia and areflexia. Hum Mol Genet. 2018 11 01; 27(21):3669-3674.
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