 Macromolecular Substances
"Macromolecular Substances" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds and molecular complexes that consist of very large numbers of atoms and are generally over 500 kDa in size. In biological systems macromolecular substances usually can be visualized using ELECTRON MICROSCOPY and are distinguished from ORGANELLES by the lack of a membrane structure.
| Descriptor ID |
D046911
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| MeSH Number(s) |
D05
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Macromolecular Substances".
Below are MeSH descriptors whose meaning is more specific than "Macromolecular Substances".
This graph shows the total number of publications written about "Macromolecular Substances" by people in this website by year, and whether "Macromolecular Substances" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 0 | 2 | 2 | | 1982 | 0 | 3 | 3 | | 1983 | 0 | 1 | 1 | | 1984 | 0 | 6 | 6 | | 1985 | 0 | 3 | 3 | | 1987 | 0 | 1 | 1 | | 1988 | 0 | 7 | 7 | | 1989 | 0 | 3 | 3 | | 1990 | 0 | 7 | 7 | | 1991 | 0 | 6 | 6 | | 1992 | 0 | 5 | 5 | | 1993 | 0 | 9 | 9 | | 1994 | 0 | 12 | 12 | | 1995 | 0 | 10 | 10 | | 1996 | 0 | 6 | 6 | | 1997 | 0 | 5 | 5 | | 1998 | 0 | 6 | 6 | | 1999 | 0 | 6 | 6 | | 2000 | 0 | 5 | 5 | | 2001 | 1 | 7 | 8 | | 2002 | 0 | 9 | 9 | | 2003 | 0 | 7 | 7 | | 2004 | 0 | 5 | 5 | | 2005 | 0 | 2 | 2 | | 2006 | 1 | 1 | 2 | | 2007 | 0 | 1 | 1 | | 2008 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2010 | 1 | 0 | 1 | | 2011 | 3 | 1 | 4 | | 2012 | 1 | 0 | 1 | | 2013 | 1 | 1 | 2 | | 2014 | 1 | 0 | 1 | | 2015 | 0 | 1 | 1 | | 2016 | 2 | 1 | 3 |
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Below are the most recent publications written about "Macromolecular Substances" by people in Profiles.
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Almassalha LM, Bauer GM, Chandler JE, Gladstein S, Cherkezyan L, Stypula-Cyrus Y, Weinberg S, Zhang D, Thusgaard Ruhoff P, Roy HK, Subramanian H, Chandel NS, Szleifer I, Backman V. Label-free imaging of the native, living cellular nanoarchitecture using partial-wave spectroscopic microscopy. Proc Natl Acad Sci U S A. 2016 10 18; 113(42):E6372-E6381.
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Meyer PA, Socias S, Key J, Ransey E, Tjon EC, Buschiazzo A, Lei M, Botka C, Withrow J, Neau D, Rajashankar K, Anderson KS, Baxter RH, Blacklow SC, Boggon TJ, Bonvin AM, Borek D, Brett TJ, Caflisch A, Chang CI, Chazin WJ, Corbett KD, Cosgrove MS, Crosson S, Dhe-Paganon S, Di Cera E, Drennan CL, Eck MJ, Eichman BF, Fan QR, Ferré-D'Amaré AR, Fromme JC, Garcia KC, Gaudet R, Gong P, Harrison SC, Heldwein EE, Jia Z, Keenan RJ, Kruse AC, Kvansakul M, McLellan JS, Modis Y, Nam Y, Otwinowski Z, Pai EF, Pereira PJ, Petosa C, Raman CS, Rapoport TA, Roll-Mecak A, Rosen MK, Rudenko G, Schlessinger J, Schwartz TU, Shamoo Y, Sondermann H, Tao YJ, Tolia NH, Tsodikov OV, Westover KD, Wu H, Foster I, Fraser JS, Maia FR, Gonen T, Kirchhausen T, Diederichs K, Crosas M, Sliz P. Data publication with the structural biology data grid supports live analysis. Nat Commun. 2016 Mar 07; 7:10882.
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Nguyen TH, Galej WP, Fica SM, Lin PC, Newman AJ, Nagai K. CryoEM structures of two spliceosomal complexes: starter and dessert at the spliceosome feast. Curr Opin Struct Biol. 2016 Feb; 36:48-57.
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Ling L, Montaño SP, Sauer RT, Rice PA, Baker TA. Deciphering the Roles of Multicomponent Recognition Signals by the AAA+ Unfoldase ClpX. J Mol Biol. 2015 Sep 11; 427(18):2966-82.
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Hudalla GA, Sun T, Gasiorowski JZ, Han H, Tian YF, Chong AS, Collier JH. Gradated assembly of multiple proteins into supramolecular nanomaterials. Nat Mater. 2014 Aug; 13(8):829-36.
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Thomer L, Schneewind O, Missiakas D. Multiple ligands of von Willebrand factor-binding protein (vWbp) promote Staphylococcus aureus clot formation in human plasma. J Biol Chem. 2013 Sep 27; 288(39):28283-92.
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Gu H, Zheng Y, Roizman B. Interaction of herpes simplex virus ICP0 with ND10 bodies: a sequential process of adhesion, fusion, and retention. J Virol. 2013 Sep; 87(18):10244-54.
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Roux B. Ion binding sites and their representations by reduced models. J Phys Chem B. 2012 Jun 14; 116(23):6966-79.
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Ren Z, Srajer V, Knapp JE, Royer WE. Cooperative macromolecular device revealed by meta-analysis of static and time-resolved structures. Proc Natl Acad Sci U S A. 2012 Jan 03; 109(1):107-12.
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Spudich JA, Rice SE, Rock RS, Purcell TJ, Warrick HM. Optical traps to study properties of molecular motors. Cold Spring Harb Protoc. 2011 Nov 01; 2011(11):1305-18.
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