Macromolecular Substances
"Macromolecular Substances" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds and molecular complexes that consist of very large numbers of atoms and are generally over 500 kDa in size. In biological systems macromolecular substances usually can be visualized using ELECTRON MICROSCOPY and are distinguished from ORGANELLES by the lack of a membrane structure.
| Descriptor ID |
D046911
|
| MeSH Number(s) |
D05
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Macromolecular Substances".
Below are MeSH descriptors whose meaning is more specific than "Macromolecular Substances".
This graph shows the total number of publications written about "Macromolecular Substances" by people in this website by year, and whether "Macromolecular Substances" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 0 | 9 | 9 |
| 1994 | 0 | 9 | 9 |
| 1995 | 0 | 10 | 10 |
| 1996 | 0 | 4 | 4 |
| 1997 | 0 | 5 | 5 |
| 1998 | 0 | 5 | 5 |
| 1999 | 0 | 6 | 6 |
| 2000 | 0 | 4 | 4 |
| 2001 | 1 | 7 | 8 |
| 2002 | 0 | 8 | 8 |
| 2003 | 0 | 6 | 6 |
| 2004 | 0 | 5 | 5 |
| 2005 | 0 | 2 | 2 |
| 2006 | 1 | 1 | 2 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 3 | 1 | 4 |
| 2012 | 1 | 1 | 2 |
| 2013 | 2 | 1 | 3 |
| 2014 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 2 | 1 | 3 |
| 2019 | 1 | 2 | 3 |
| 2020 | 0 | 1 | 1 |
| 2021 | 1 | 1 | 2 |
| 2023 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Macromolecular Substances" by people in Profiles.
-
Developmental and regional dependence of macromolecular proton fraction and fractional anisotropy in fixed brain tissue. NMR Biomed. 2023 07; 36(7):e4915.
-
100th Anniversary of Macromolecular Science Viewpoint: Data-Driven Protein Design. ACS Macro Lett. 2021 03 16; 10(3):327-340.
-
In Situ Imaging and Structure Determination of Biomolecular Complexes Using Electron Cryo-Tomography. Methods Mol Biol. 2021; 2215:83-111.
-
Disordered chromatin packing regulates phenotypic plasticity. Sci Adv. 2020 01; 6(2):eaax6232.
-
Self-organizing motors divide active liquid droplets. Proc Natl Acad Sci U S A. 2019 06 04; 116(23):11125-11130.
-
Characterizing Watson-Crick versus Hoogsteen Base Pairing in a DNA-Protein Complex Using Nuclear Magnetic Resonance and Site-Specifically 13C- and 15N-Labeled DNA. Biochemistry. 2019 04 16; 58(15):1963-1974.
-
In Situ Imaging and Structure Determination of Bacterial Toxin Delivery Systems Using Electron Cryotomography. Methods Mol Biol. 2019; 1921:249-265.
-
Label-free imaging of the native, living cellular nanoarchitecture using partial-wave spectroscopic microscopy. Proc Natl Acad Sci U S A. 2016 10 18; 113(42):E6372-E6381.
-
Data publication with the structural biology data grid supports live analysis. Nat Commun. 2016 Mar 07; 7:10882.
-
CryoEM structures of two spliceosomal complexes: starter and dessert at the spliceosome feast. Curr Opin Struct Biol. 2016 Feb; 36:48-57.