 Small-Conductance Calcium-Activated Potassium Channels
"Small-Conductance Calcium-Activated Potassium Channels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A major class of calcium-activated potassium channels that are found primarily in excitable CELLS. They play important roles in the transmission of ACTION POTENTIALS and generate a long-lasting hyperpolarization known as the slow afterhyperpolarization.
| Descriptor ID |
D051640
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| MeSH Number(s) |
D12.776.157.530.400.600.150.750 D12.776.543.550.425.750.150.750 D12.776.543.585.400.750.150.750
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Small-Conductance Calcium-Activated Potassium Channels".
Below are MeSH descriptors whose meaning is more specific than "Small-Conductance Calcium-Activated Potassium Channels".
This graph shows the total number of publications written about "Small-Conductance Calcium-Activated Potassium Channels" by people in this website by year, and whether "Small-Conductance Calcium-Activated Potassium Channels" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 2000 | 0 | 1 | 1 | | 2001 | 0 | 1 | 1 | | 2002 | 0 | 2 | 2 | | 2003 | 0 | 1 | 1 | | 2010 | 0 | 1 | 1 | | 2012 | 1 | 1 | 2 | | 2016 | 0 | 1 | 1 | | 2020 | 3 | 1 | 4 |
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Below are the most recent publications written about "Small-Conductance Calcium-Activated Potassium Channels" by people in Profiles.
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Mochel F, Rastetter A, Ceulemans B, Platzer K, Yang S, Shinde DN, Helbig KL, Lopergolo D, Mari F, Renieri A, Benetti E, Canitano R, Waisfisz Q, Plomp AS, Huisman SA, Wilson GN, Cathey SS, Louie RJ, Gaudio DD, Waggoner D, Kacker S, Nugent KM, Roeder ER, Bruel AL, Thevenon J, Ehmke N, Horn D, Holtgrewe M, Kaiser FJ, Kamphausen SB, Abou Jamra R, Weckhuysen S, Dalle C, Depienne C. Variants in the SK2 channel gene (KCNN2) lead to dominant neurodevelopmental movement disorders. Brain. 2020 12 01; 143(12):3564-3573.
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Gill DF, Hansel C. Muscarinic Modulation of SK2-Type K+ Channels Promotes Intrinsic Plasticity in L2/3 Pyramidal Neurons of the Mouse Primary Somatosensory Cortex. eNeuro. 2020 Mar/Apr; 7(2).
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Titley HK, Watkins GV, Lin C, Weiss C, McCarthy M, Disterhoft JF, Hansel C. Intrinsic Excitability Increase in Cerebellar Purkinje Cells after Delay Eye-Blink Conditioning in Mice. J Neurosci. 2020 03 04; 40(10):2038-2046.
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Grasselli G, Boele HJ, Titley HK, Bradford N, van Beers L, Jay L, Beekhof GC, Busch SE, De Zeeuw CI, Schonewille M, Hansel C. SK2 channels in cerebellar Purkinje cells contribute to excitability modulation in motor-learning-specific memory traces. PLoS Biol. 2020 01; 18(1):e3000596.
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Grasselli G, He Q, Wan V, Adelman JP, Ohtsuki G, Hansel C. Activity-Dependent Plasticity of Spike Pauses in Cerebellar Purkinje Cells. Cell Rep. 2016 Mar 22; 14(11):2546-53.
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Ohtsuki G, Piochon C, Adelman JP, Hansel C. SK2 channel modulation contributes to compartment-specific dendritic plasticity in cerebellar Purkinje cells. Neuron. 2012 Jul 12; 75(1):108-20.
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McCutcheon JE, Conrad KL, Carr SB, Ford KA, McGehee DS, Marinelli M. Dopamine neurons in the ventral tegmental area fire faster in adolescent rats than in adults. J Neurophysiol. 2012 Sep; 108(6):1620-30.
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Rinaldo L, Hansel C. Ataxias and cerebellar dysfunction: involvement of synaptic plasticity deficits? Funct Neurol. 2010 Jul-Sep; 25(3):135-9.
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Tamarina NA, Wang Y, Mariotto L, Kuznetsov A, Bond C, Adelman J, Philipson LH. Small-conductance calcium-activated K+ channels are expressed in pancreatic islets and regulate glucose responses. Diabetes. 2003 Aug; 52(8):2000-6.
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Couey JJ, Ryan DP, Glover JT, Dreixler JC, Young JB, Houamed KM. Giant excised patch recordings of recombinant ion channel currents expressed in mammalian cells. Neurosci Lett. 2002 Aug 23; 329(1):17-20.
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