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Molly Przeworski

TitlePROFESSOR
InstitutionUniversity of Chicago
DepartmentHuman Genetics
AddressChicago IL 60637
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    Collapse Research 
    Collapse research activities and funding
    R35GM153355     (PRZEWORSKI, MOLLY F)Apr 1, 2024 - Mar 31, 2029
    NIH
    Mechanisms of mutation and recombination and their evolution in vertebrates
    Role: Principal Investigator
    R01GM122975     (PRZEWORSKI, MOLLY F)May 15, 2017 - Mar 31, 2021
    NIH
    Mutation rate variation in primates
    Role: Principal Investigator
    R01GM121372     (PRZEWORSKI, MOLLY F)Mar 8, 2017 - Dec 31, 2021
    NIH
    Natural selection in recent human evolution
    Role: Principal Investigator
    R01GM083098     (PRZEWORSKI, MOLLY F)Sep 17, 2007 - Dec 31, 2024
    NIH
    Recombination rate variation and evolution in vertebrates
    Role: Principal Investigator
    R01GM072861     (PRZEWORSKI, MOLLY F)Mar 1, 2005 - Feb 28, 2011
    NIH
    Identifying human adaptations: theory and applications
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Veller C, Przeworski M, Coop G. Causal interpretations of family GWAS in the presence of heterogeneous effects. Proc Natl Acad Sci U S A. 2024 Sep 17; 121(38):e2401379121. PMID: 39269774; PMCID: PMC11420194.
      Citations:    Fields:    Translation:Humans
    2. Prentout D, Bykova D, Hoge C, Hooper DM, McDiarmid CS, Wu F, Griffith SC, de Manuel M, Przeworski M. Conservation of mutation and recombination parameters between mammals and zebra finch. bioRxiv. 2024 Sep 05. PMID: 39282267; PMCID: PMC11398497.
      Citations:    
    3. Spisak N, de Manuel M, Milligan W, Sella G, Przeworski M. The clock-like accumulation of germline and somatic mutations can arise from the interplay of DNA damage and repair. PLoS Biol. 2024 Jun; 22(6):e3002678. PMID: 38885262; PMCID: PMC11213356.
      Citations: 1     Fields:    Translation:HumansCells
    4. Przeworski M. 2023 ASHG Scientific Achievement Award. Am J Hum Genet. 2024 Mar 07; 111(3):425-427. PMID: 38458164; PMCID: PMC10995464.
      Citations:    Fields:    Translation:Humans
    5. Hoge C, de Manuel M, Mahgoub M, Okami N, Fuller Z, Banerjee S, Baker Z, McNulty M, Andolfatto P, Macfarlan TS, Schumer M, Tzika AC, Przeworski M. Patterns of recombination in snakes reveal a tug-of-war between PRDM9 and promoter-like features. Science. 2024 Feb 23; 383(6685):eadj7026. PMID: 38386752.
      Citations: 9     Fields:    Translation:AnimalsCells
    6. Veller C, Przeworski M, Coop G. Causal interpretations of family GWAS in the presence of heterogeneous effects. bioRxiv. 2023 Nov 16. PMID: 38014124; PMCID: PMC10680648.
      Citations:    
    7. Baker Z, Przeworski M, Sella G. Down the Penrose stairs, or how selection for fewer recombination hotspots maintains their existence. Elife. 2023 Oct 13; 12. PMID: 37830496; PMCID: PMC10703446.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    8. Spisak N, de Manuel M, Milligan W, Sella G, Przeworski M. Disentangling sources of clock-like mutations in germline and soma. bioRxiv. 2023 Sep 12. PMID: 37745549; PMCID: PMC10515775.
      Citations:    
    9. Hoge C, de Manuel M, Mahgoub M, Okami N, Fuller Z, Banerjee S, Baker Z, McNulty M, Andolfatto P, Macfarlan TS, Schumer M, Tzika AC, Przeworski M. Patterns of recombination in snakes reveal a tug of war between PRDM9 and promoter-like features. bioRxiv. 2023 Jul 11. PMID: 37502971; PMCID: PMC10369914.
      Citations:    
    10. Gao Z, Zhang Y, Cramer N, Przeworski M, Moorjani P. Limited role of generation time changes in driving the evolution of the mutation spectrum in humans. Elife. 2023 02 13; 12. PMID: 36779395; PMCID: PMC10014080.
      Citations: 7     Fields:    Translation:Humans
    11. Agarwal I, Fuller ZL, Myers SR, Przeworski M. Relating pathogenic loss-of-function mutations in humans to their evolutionary fitness costs. Elife. 2023 01 17; 12. PMID: 36648429; PMCID: PMC9937649.
      Citations: 18     Fields:    Translation:Humans
    12. Coop G, Przeworski M. Luck, lottery, or legacy? The problem of confounding. A reply to Harden. Evolution. 2022 10; 76(10):2464-2468. PMID: 35915930; PMCID: PMC9627830.
      Citations: 3     Fields:    
    13. de Manuel M, Wu FL, Przeworski M. A paternal bias in germline mutation is widespread in amniotes and can arise independently of cell division numbers. Elife. 2022 08 02; 11. PMID: 35916372; PMCID: PMC9439683.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    14. Coop G, Przeworski M. Lottery, luck, or legacy. A review of "The Genetic Lottery: Why DNA matters for social equality". Evolution. 2022 04 01; 76(4):846-853. PMID: 35225362; PMCID: PMC9313868.
      Citations: 11     Fields:    Translation:Humans
    15. Cavassim MIA, Baker Z, Hoge C, Schierup MH, Schumer M, Przeworski M. PRDM9 losses in vertebrates are coupled to those of paralogs ZCWPW1 and ZCWPW2. Proc Natl Acad Sci U S A. 2022 03 01; 119(9). PMID: 35217607; PMCID: PMC8892340.
      Citations: 12     Fields:    Translation:HumansAnimals
    16. Agarwal I, Przeworski M. Mutation saturation for fitness effects at human CpG sites. Elife. 2021 11 22; 10. PMID: 34806592; PMCID: PMC8683084.
      Citations: 20     Fields:    Translation:HumansCells
    17. Milligan WR, Fuller ZL, Agarwal I, Eisen MB, Przeworski M, Sella G. Impact of essential workers in the context of social distancing for epidemic control. PLoS One. 2021; 16(8):e0255680. PMID: 34347855; PMCID: PMC8336873.
      Citations: 7     Fields:    Translation:HumansPHPublic Health
    18. Harpak A, Przeworski M. The evolution of group differences in changing environments. PLoS Biol. 2021 01; 19(1):e3001072. PMID: 33493148; PMCID: PMC7861633.
      Citations: 23     Fields:    Translation:HumansAnimals
    19. Wu FL, Strand AI, Cox LA, Ober C, Wall JD, Moorjani P, Przeworski M. A comparison of humans and baboons suggests germline mutation rates do not track cell divisions. PLoS Biol. 2020 08; 18(8):e3000838. PMID: 32804933; PMCID: PMC7467331.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    20. Fuller ZL, Mocellin VJL, Morris LA, Cantin N, Shepherd J, Sarre L, Peng J, Liao Y, Pickrell J, Andolfatto P, Matz M, Bay LK, Przeworski M. Population genetics of the coral Acropora millepora: Toward genomic prediction of bleaching. Science. 2020 07 17; 369(6501). PMID: 32675347.
      Citations: 68     Fields:    Translation:Animals
    21. Mostafavi H, Harpak A, Agarwal I, Conley D, Pritchard JK, Przeworski M. Variable prediction accuracy of polygenic scores within an ancestry group. Elife. 2020 01 30; 9. PMID: 31999256; PMCID: PMC7067566.
      Citations: 189     Fields:    Translation:Humans
    22. Young AI, Benonisdottir S, Przeworski M, Kong A. Deconstructing the sources of genotype-phenotype associations in humans. Science. 2019 09 27; 365(6460):1396-1400. PMID: 31604265; PMCID: PMC6894903.
      Citations: 105     Fields:    Translation:Humans
    23. Sasani TA, Pedersen BS, Gao Z, Baird L, Przeworski M, Jorde LB, Quinlan AR. Large, three-generation human families reveal post-zygotic mosaicism and variability in germline mutation accumulation. Elife. 2019 09 24; 8. PMID: 31549960; PMCID: PMC6759356.
      Citations: 84     Fields:    Translation:Humans
    24. Agarwal I, Przeworski M. Signatures of replication timing, recombination, and sex in the spectrum of rare variants on the human X chromosome and autosomes. Proc Natl Acad Sci U S A. 2019 09 03; 116(36):17916-17924. PMID: 31427530; PMCID: PMC6731651.
      Citations: 25     Fields:    Translation:HumansCells
    25. Gao Z, Moorjani P, Sasani TA, Pedersen BS, Quinlan AR, Jorde LB, Amster G, Przeworski M. Overlooked roles of DNA damage and maternal age in generating human germline mutations. Proc Natl Acad Sci U S A. 2019 05 07; 116(19):9491-9500. PMID: 31019089; PMCID: PMC6511033.
      Citations: 90     Fields:    Translation:HumansCells
    26. Fuller ZL, Berg JJ, Mostafavi H, Sella G, Przeworski M. Measuring intolerance to mutation in human genetics. Nat Genet. 2019 05; 51(5):772-776. PMID: 30962618; PMCID: PMC6615471.
      Citations: 64     Fields:    Translation:HumansAnimals
    27. Amorim CEG, Gao Z, Baker Z, Simons YB, Haque IS, Pickrell J, Przeworski M, Diesel JF. Correction: The population genetics of human disease: The case of recessive, lethal mutations. PLoS Genet. 2018 07; 14(7):e1007499. PMID: 29965964; PMCID: PMC6028076.
      Citations:    Fields:    
    28. Schumer M, Xu C, Durvasula A, Skov L, Blazier JC, Sankararaman S, Andolfatto P, Przeworski M, Powell DL, Holland C, Rosenthal GG. Natural selection interacts with recombination to shape the evolution of hybrid genomes. Science. 2018 May 11; 360(6389):656-660. PMID: 29674434; PMCID: PMC6069607.
      Citations: 158     Fields:    Translation:Animals
    29. Amorim CEG, Gao Z, Baker Z, Simons YB, Haque IS, Pickrell J, Przeworski M, Diesel JF. The population genetics of human disease: The case of recessive, lethal mutations. PLoS Genet. 2017 Sep; 13(9):e1006915. PMID: 28957316; PMCID: PMC5619689.
      Citations: 21     Fields:    Translation:Humans
    30. Mostafavi H, Berisa T, Day FR, Perry JRB, Przeworski M, Pickrell JK. Identifying genetic variants that affect viability in large cohorts. PLoS Biol. 2017 Sep; 15(9):e2002458. PMID: 28873088; PMCID: PMC5584811.
      Citations: 36     Fields:    Translation:Humans
    31. Chen C, Qi H, Shen Y, Pickrell J, Przeworski M. Contrasting Determinants of Mutation Rates in Germline and Soma. Genetics. 2017 09; 207(1):255-267. PMID: 28733365; PMCID: PMC5586376.
      Citations: 13     Fields:    Translation:Humans
    32. Baker Z, Schumer M, Haba Y, Bashkirova L, Przeworski M, Holland C, Rosenthal GG. Repeated losses of PRDM9-directed recombination despite the conservation of PRDM9 across vertebrates. Elife. 2017 06 06; 6. PMID: 28590247; PMCID: PMC5519329.
      Citations: 75     Fields:    Translation:Animals
    33. Moorjani P, Gao Z, Przeworski M. Human Germline Mutation and the Erratic Evolutionary Clock. PLoS Biol. 2016 Oct; 14(10):e2000744. PMID: 27760127; PMCID: PMC5070741.
      Citations: 29     Fields:    Translation:Humans
    34. Moorjani P, Amorim CE, Arndt PF, Przeworski M. Variation in the molecular clock of primates. Proc Natl Acad Sci U S A. 2016 09 20; 113(38):10607-12. PMID: 27601674; PMCID: PMC5035889.
      Citations: 85     Fields:    Translation:HumansAnimalsCells
    35. Moorjani P, Sankararaman S, Fu Q, Przeworski M, Patterson N, Reich D. A genetic method for dating ancient genomes provides a direct estimate of human generation interval in the last 45,000 years. Proc Natl Acad Sci U S A. 2016 May 17; 113(20):5652-7. PMID: 27140627; PMCID: PMC4878468.
      Citations: 65     Fields:    Translation:HumansAnimals
    36. Gao Z, Wyman MJ, Sella G, Przeworski M. Interpreting the Dependence of Mutation Rates on Age and Time. PLoS Biol. 2016 Jan; 14(1):e1002355. PMID: 26761240; PMCID: PMC4711947.
      Citations: 67     Fields:    Translation:HumansAnimalsCells
    37. Morton ER, Lynch J, Froment A, Lafosse S, Heyer E, Przeworski M, Blekhman R, Ségurel L. Variation in Rural African Gut Microbiota Is Strongly Correlated with Colonization by Entamoeba and Subsistence. PLoS Genet. 2015 Nov; 11(11):e1005658. PMID: 26619199; PMCID: PMC4664238.
      Citations: 104     Fields:    Translation:HumansAnimals
    38. Singhal S, Leffler EM, Sannareddy K, Turner I, Venn O, Hooper DM, Strand AI, Li Q, Raney B, Balakrishnan CN, Griffith SC, McVean G, Przeworski M. Stable recombination hotspots in birds. Science. 2015 11 20; 350(6263):928-32. PMID: 26586757; PMCID: PMC4864528.
      Citations: 148     Fields:    Translation:Animals
    39. Meyer WK, Venkat A, Kermany AR, van de Geijn B, Zhang S, Przeworski M. Evolutionary history inferred from the de novo assembly of a nonmodel organism, the blue-eyed black lemur. Mol Ecol. 2015 Sep; 24(17):4392-405. PMID: 26198179; PMCID: PMC4557055.
      Citations: 13     Fields:    Translation:Animals
    40. Williams AL, Genovese G, Dyer T, Altemose N, Truax K, Jun G, Patterson N, Myers SR, Curran JE, Duggirala R, Blangero J, Reich D, Przeworski M, T2D-GENES Consortium. Non-crossover gene conversions show strong GC bias and unexpected clustering in humans. Elife. 2015 Mar 25; 4. PMID: 25806687; PMCID: PMC4404656.
      Citations: 59     Fields:    Translation:HumansCells
    41. Gao Z, Waggoner D, Stephens M, Ober C, Przeworski M. An estimate of the average number of recessive lethal mutations carried by humans. Genetics. 2015 Apr; 199(4):1243-54. PMID: 25697177; PMCID: PMC4391560.
      Citations: 34     Fields:    Translation:Humans
    42. Gao Z, Przeworski M, Sella G. Footprints of ancient-balanced polymorphisms in genetic variation data from closely related species. Evolution. 2015 Feb; 69(2):431-46. PMID: 25403856; PMCID: PMC4335603.
      Citations: 35     Fields:    Translation:HumansAnimals
    43. Wyman MJ, Przeworski M, Ségurel L. Determinants of mutation rate variation in the human germline. Annu Rev Genomics Hum Genet. 2014; 15:47-70. PMID: 25000986.
      Citations: 153     Fields:    Translation:HumansAnimals
    44. Kermany AR, Segurel L, Oliver TR, Przeworski M. TroX: a new method to learn about the genesis of aneuploidy from trisomic products of conception. Bioinformatics. 2014 Jul 15; 30(14):2035-42. PMID: 24659032; PMCID: PMC4080739.
      Citations: 1     Fields:    Translation:Humans
    45. Wilson D, Laval G, Patin E, Manry J, Guibert J, Barreiro LB, Nerrienet E, Verschoor E, Gessain A, Przeworski M, Quintana-Murci L, Quach H. Different selective pressures shape the evolution of Toll-like receptors in human and African great ape populations. Hum Mol Genet. 2013 Dec 01; 22(23):4829-40. PMID: 23851028; PMCID: PMC3820138.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    46. Gao Z, Przeworski M, Ségurel L. Ancestry runs deeper than blood: the evolutionary history of ABO points to cryptic variation of functional importance. Bioessays. 2013 Oct; 35(10):862-7. PMID: 23836453; PMCID: PMC4034584.
      Citations: 19     Fields:    Translation:HumansAnimals
    47. Meyer WK, Zhang S, Hayakawa S, Imai H, Przeworski M. The convergent evolution of blue iris pigmentation in primates took distinct molecular paths. Am J Phys Anthropol. 2013 Jul; 151(3):398-407. PMID: 23640739; PMCID: PMC3746105.
      Citations: 6     Fields:    Translation:HumansAnimals
    48. Leffler EM, Gao Z, Pfeifer S, Auton A, Venn O, Bowden R, Bontrop R, Wall JD, Sella G, Donnelly P, McVean G, Przeworski M, Ségurel L. Multiple instances of ancient balancing selection shared between humans and chimpanzees. Science. 2013 Mar 29; 339(6127):1578-82. PMID: 23413192; PMCID: PMC3612375.
      Citations: 156     Fields:    Translation:HumansAnimalsCells
    49. Thompson EE, Lovstad J, Venkat A, Margulis SW, Moyse J, Ross S, Gamble K, Sella G, Ober C, Przeworski M, Ségurel L, Flutre T. The ABO blood group is a trans-species polymorphism in primates. Proc Natl Acad Sci U S A. 2012 Nov 06; 109(45):18493-8. PMID: 23091028; PMCID: PMC3494955.
      Citations: 71     Fields:    Translation:Animals
    50. Leffler EM, Bullaughey K, Matute DR, Meyer WK, Venkat A, Andolfatto P, Przeworski M, Ségurel L. Revisiting an old riddle: what determines genetic diversity levels within species? PLoS Biol. 2012; 10(9):e1001388. PMID: 22984349; PMCID: PMC3439417.
      Citations: 229     Fields:    Translation:AnimalsCells
    51. Auton A, Fledel-Alon A, Pfeifer S, Venn O, Street T, Leffler EM, Bowden R, Aneas I, Broxholme J, Humburg P, Iqbal Z, Lunter G, Maller J, Hernandez RD, Melton C, Venkat A, Nobrega MA, Bontrop R, Myers S, Donnelly P, Przeworski M, McVean G, Ségurel L. A fine-scale chimpanzee genetic map from population sequencing. Science. 2012 Apr 13; 336(6078):193-8. PMID: 22422862; PMCID: PMC3532813.
      Citations: 181     Fields:    Translation:HumansAnimalsCells
    52. Meyer WK, Arbeithuber B, Ober C, Ebner T, Tiemann-Boege I, Hudson RR, Przeworski M. Evaluating the evidence for transmission distortion in human pedigrees. Genetics. 2012 May; 191(1):215-32. PMID: 22377632; PMCID: PMC3338262.
      Citations: 27     Fields:    Translation:HumansCells
    53. Leffler EM, Przeworski M, Ségurel L. The case of the fickle fingers: how the PRDM9 zinc finger protein specifies meiotic recombination hotspots in humans. PLoS Biol. 2011 Dec; 9(12):e1001211. PMID: 22162947; PMCID: PMC3232208.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    54. Wilson DJ, Hernandez RD, Andolfatto P, Przeworski M. A population genetics-phylogenetics approach to inferring natural selection in coding sequences. PLoS Genet. 2011 Dec; 7(12):e1002395. PMID: 22144911; PMCID: PMC3228810.
      Citations: 55     Fields:    Translation:Animals
    55. Fledel-Alon A, Leffler EM, Guan Y, Stephens M, Coop G, Przeworski M. Variation in human recombination rates and its genetic determinants. PLoS One. 2011; 6(6):e20321. PMID: 21698098; PMCID: PMC3117798.
      Citations: 68     Fields:    Translation:Humans
    56. Hernandez RD, Kelley JL, Elyashiv E, Melton SC, Auton A, McVean G, 1000 Genomes Project, Sella G, Przeworski M. Classic selective sweeps were rare in recent human evolution. Science. 2011 Feb 18; 331(6019):920-4. PMID: 21330547; PMCID: PMC3669691.
      Citations: 233     Fields:    Translation:HumansCells
    57. Przeworski M. Genome-sequencing anniversary. The golden age of human population genetics. Science. 2011 Feb 04; 331(6017):547. PMID: 21292966.
      Citations: 1     Fields:    Translation:HumansAnimals
    58. Elyashiv E, Bullaughey K, Sattath S, Rinott Y, Przeworski M, Sella G. Shifts in the intensity of purifying selection: an analysis of genome-wide polymorphism data from two closely related yeast species. Genome Res. 2010 Nov; 20(11):1558-73. PMID: 20817943; PMCID: PMC2963819.
      Citations: 44     Fields:    Translation:Animals
    59. Buard J, Grey C, Fledel-Alon A, Ober C, Przeworski M, Coop G, de Massy B, Baudat F. PRDM9 is a major determinant of meiotic recombination hotspots in humans and mice. Science. 2010 Feb 12; 327(5967):836-40. PMID: 20044539; PMCID: PMC4295902.
      Citations: 532     Fields:    Translation:HumansAnimalsCells
    60. Fledel-Alon A, Wilson DJ, Broman K, Wen X, Ober C, Coop G, Przeworski M. Broad-scale recombination patterns underlying proper disjunction in humans. PLoS Genet. 2009 Sep; 5(9):e1000658. PMID: 19763175; PMCID: PMC2734982.
      Citations: 63     Fields:    Translation:HumansCells
    61. Sella G, Petrov DA, Przeworski M, Andolfatto P. Pervasive natural selection in the Drosophila genome? PLoS Genet. 2009 Jun; 5(6):e1000495. PMID: 19503600; PMCID: PMC2684638.
      Citations: 200     Fields:    Translation:Animals
    62. Przeworski M, Becquet C. Learning about modes of speciation by computational approaches. Evolution. 2009 Oct; 63(10):2547-62. PMID: 19228187.
      Citations: 42     Fields:    
    63. Blekhman R, Man O, Herrmann L, Boyko AR, Indap A, Kosiol C, Bustamante CD, Teshima KM, Przeworski M. Natural selection on genes that underlie human disease susceptibility. Curr Biol. 2008 Jun 24; 18(12):883-9. PMID: 18571414; PMCID: PMC2474766.
      Citations: 127     Fields:    Translation:HumansAnimals
    64. Coop G, Bullaughey K, Luca F, Przeworski M. The timing of selection at the human FOXP2 gene. Mol Biol Evol. 2008 Jul; 25(7):1257-9. PMID: 18413354; PMCID: PMC2429961.
      Citations: 28     Fields:    Translation:Humans
    65. Coop G, Wen X, Ober C, Pritchard JK, Przeworski M. High-resolution mapping of crossovers reveals extensive variation in fine-scale recombination patterns among humans. Science. 2008 Mar 07; 319(5868):1395-8. PMID: 18239090.
      Citations: 219     Fields:    Translation:Humans
    66. Bullaughey K, Przeworski M, Coop G. No effect of recombination on the efficacy of natural selection in primates. Genome Res. 2008 Apr; 18(4):544-54. PMID: 18199888; PMCID: PMC2279242.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    67. Becquet C, Przeworski M. A new approach to estimate parameters of speciation models with application to apes. Genome Res. 2007 Oct; 17(10):1505-19. PMID: 17712021; PMCID: PMC1987350.
      Citations: 102     Fields:    Translation:Animals
    68. Becquet C, Patterson N, Stone AC, Przeworski M, Reich D. Genetic structure of chimpanzee populations. PLoS Genet. 2007 Apr 20; 3(4):e66. PMID: 17447846; PMCID: PMC1853122.
      Citations: 71     Fields:    Translation:Animals
    69. Clark VJ, Ptak SE, Tiemann I, Qian Y, Coop G, Stone AC, Przeworski M, Arnheim N, Di Rienzo A. Combining sperm typing and linkage disequilibrium analyses reveals differences in selective pressures or recombination rates across human populations. Genetics. 2007 Feb; 175(2):795-804. PMID: 17151245; PMCID: PMC1800598.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    70. Coop G, Przeworski M. An evolutionary view of human recombination. Nat Rev Genet. 2007 Jan; 8(1):23-34. PMID: 17146469.
      Citations: 163     Fields:    Translation:HumansAnimals
    71. Teshima KM, Coop G, Przeworski M. How reliable are empirical genomic scans for selective sweeps? Genome Res. 2006 Jun; 16(6):702-12. PMID: 16687733; PMCID: PMC1473181.
      Citations: 194     Fields:    Translation:HumansAnimals
    72. Przeworski M, Coop G, Wall JD. The signature of positive selection on standing genetic variation. Evolution. 2005 Nov; 59(11):2312-23. PMID: 16396172.
      Citations: 234     Fields:    
    73. Przeworski M. Genetics. Motivating hotspots. Science. 2005 Oct 14; 310(5746):247-8. PMID: 16224010.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    74. Teshima KM, Przeworski M. Directional positive selection on an allele of arbitrary dominance. Genetics. 2006 Jan; 172(1):713-8. PMID: 16219788; PMCID: PMC1456198.
      Citations: 43     Fields:    
    75. Schulz A, Pitra C, Coop G, Przeworski M, Römpler H, Pääbo S, Schöneberg T. The rise and fall of the chemoattractant receptor GPR33. J Biol Chem. 2005 Sep 02; 280(35):31068-75. PMID: 15987686.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    76. Ptak SE, Hinds DA, Koehler K, Nickel B, Patil N, Ballinger DG, Przeworski M, Frazer KA, Pääbo S. Fine-scale recombination patterns differ between chimpanzees and humans. Nat Genet. 2005 Apr; 37(4):429-34. PMID: 15723063.
      Citations: 142     Fields:    Translation:HumansAnimals
    77. Ptak SE, Roeder AD, Stephens M, Gilad Y, Przeworski M, Pääbo S. Absence of the TAP2 human recombination hotspot in chimpanzees. PLoS Biol. 2004 Jun; 2(6):e155. PMID: 15208713; PMCID: PMC423135.
      Citations: 57     Fields:    Translation:HumansAnimalsCells
    78. Ptak SE, Voelpel K, Przeworski M. Insights into recombination from patterns of linkage disequilibrium in humans. Genetics. 2004 May; 167(1):387-97. PMID: 15166163; PMCID: PMC1470869.
      Citations: 22     Fields:    Translation:Humans
    79. Fischer A, Wiebe V, Przeworski M, Pääbo S. Evidence for a complex demographic history of chimpanzees. Mol Biol Evol. 2004 May; 21(5):799-808. PMID: 14963091.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    80. Gilad Y, Wiebe V, Przeworski M, Lancet D, Pääbo S. Loss of olfactory receptor genes coincides with the acquisition of full trichromatic vision in primates. PLoS Biol. 2004 Jan; 2(1):E5. PMID: 14737185; PMCID: PMC314465.
      Citations: 129     Fields:    Translation:HumansAnimals
    81. Przeworski M. Estimating the time since the fixation of a beneficial allele. Genetics. 2003 Aug; 164(4):1667-76. PMID: 12930770; PMCID: PMC1462667.
      Citations: 55     Fields:    Translation:AnimalsCells
    82. Hellmann I, Ebersberger I, Ptak SE, Przeworski M, Pääbo S. A neutral explanation for the correlation of diversity with recombination rates in humans. Am J Hum Genet. 2003 Jun; 72(6):1527-35. PMID: 12740762; PMCID: PMC1180312.
      Citations: 136     Fields:    Translation:HumansAnimals
    83. Ptak SE, Przeworski M. Evidence for population growth in humans is confounded by fine-scale population structure. Trends Genet. 2002 Nov; 18(11):559-63. PMID: 12414185.
      Citations: 57     Fields:    Translation:Humans
    84. Wall JD, Andolfatto P, Przeworski M. Testing models of selection and demography in Drosophila simulans. Genetics. 2002 Sep; 162(1):203-16. PMID: 12242234; PMCID: PMC1462246.
      Citations: 91     Fields:    Translation:AnimalsCells
    85. Enard W, Przeworski M, Fisher SE, Lai CS, Wiebe V, Kitano T, Monaco AP, Pääbo S. Molecular evolution of FOXP2, a gene involved in speech and language. Nature. 2002 Aug 22; 418(6900):869-72. PMID: 12192408.
      Citations: 343     Fields:    Translation:HumansAnimalsCells
    86. Przeworski M. The signature of positive selection at randomly chosen loci. Genetics. 2002 Mar; 160(3):1179-89. PMID: 11901132; PMCID: PMC1462030.
      Citations: 222     Fields:    Translation:HumansAnimals
    87. Gilad Y, Rosenberg S, Przeworski M, Lancet D, Skorecki K. Evidence for positive selection and population structure at the human MAO-A gene. Proc Natl Acad Sci U S A. 2002 Jan 22; 99(2):862-7. PMID: 11805333; PMCID: PMC117396.
      Citations: 34     Fields:    Translation:HumansAnimals
    88. Pritchard JK, Przeworski M. Linkage disequilibrium in humans: models and data. Am J Hum Genet. 2001 Jul; 69(1):1-14. PMID: 11410837; PMCID: PMC1226024.
      Citations: 448     Fields:    Translation:Humans
    89. Andolfatto P, Przeworski M. Regions of lower crossing over harbor more rare variants in African populations of Drosophila melanogaster. Genetics. 2001 Jun; 158(2):657-65. PMID: 11404330; PMCID: PMC1461661.
      Citations: 55     Fields:    Translation:AnimalsCells
    90. Przeworski M, Wall JD. Why is there so little intragenic linkage disequilibrium in humans? Genet Res. 2001 Apr; 77(2):143-51. PMID: 11355570.
      Citations: 32     Fields:    Translation:HumansCells
    91. Przeworski M, Wall JD, Andolfatto P. Recombination and the frequency spectrum in Drosophila melanogaster and Drosophila simulans. Mol Biol Evol. 2001 Mar; 18(3):291-8. PMID: 11230530.
      Citations: 28     Fields:    Translation:Animals
    92. Andolfatto P, Przeworski M. A genome-wide departure from the standard neutral model in natural populations of Drosophila. Genetics. 2000 Sep; 156(1):257-68. PMID: 10978290; PMCID: PMC1461228.
      Citations: 77     Fields:    Translation:Animals
    93. Wall JD, Przeworski M. When did the human population size start increasing? Genetics. 2000 Aug; 155(4):1865-74. PMID: 10924481; PMCID: PMC1461207.
      Citations: 44     Fields:    Translation:Humans
    94. Przeworski M, Hudson RR, Di Rienzo A. Adjusting the focus on human variation. Trends Genet. 2000 Jul; 16(7):296-302. PMID: 10858659.
      Citations: 76     Fields:    Translation:Humans
    95. Przeworski M, Charlesworth B, Wall JD. Genealogies and weak purifying selection. Mol Biol Evol. 1999 Feb; 16(2):246-52. PMID: 10084898.
      Citations: 27     Fields:    
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