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EDUARDO PEROZO

TitlePROFESSOR
InstitutionUniversity of Chicago
DepartmentBiochem/Mol Bio
AddressChicago IL 60637
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    TitlePROFESSOR
    InstitutionUniversity of Chicago
    DepartmentBiological Sciences Collegiate Division


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Zhao R, Kennedy K, De Blas GA, Orta G, Pavarotti MA, Arias RJ, de la Vega-Beltrán JL, Li Q, Dai H, Perozo E, Mayorga LS, Darszon A, Goldstein SAN. Role of human Hv1 channels in sperm capacitation and white blood cell respiratory burst established by a designed peptide inhibitor. Proc Natl Acad Sci U S A. 2018 Nov 26. PMID: 30478045.
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    2. Li J, Ostmeyer J, Cuello LG, Perozo E, Roux B. Rapid constriction of the selectivity filter underlies C-type inactivation in the KcsA potassium channel. J Gen Physiol. 2018 Oct 01; 150(10):1408-1420. PMID: 30072373.
      View in: PubMed
    3. Lau C, Hunter MJ, Stewart A, Perozo E, Vandenberg JI. Never at rest: insights into the conformational dynamics of ion channels from cryo-electron microscopy. J Physiol. 2018 Apr 01; 596(7):1107-1119. PMID: 29377132.
      View in: PubMed
    4. Bavi N, Martinac AD, Cortes DM, Bavi O, Ridone P, Nomura T, Hill AP, Martinac B, Perozo E. Structural Dynamics of the MscL C-terminal Domain. Sci Rep. 2017 Dec 08; 7(1):17229. PMID: 29222414.
      View in: PubMed
    5. Cuello LG, Cortes DM, Perozo E. The gating cycle of a K+ channel at atomic resolution. Elife. 2017 11 22; 6. PMID: 29165243.
      View in: PubMed
    6. Li J, Ostmeyer J, Boulanger E, Rui H, Perozo E, Roux B. Chemical substitutions in the selectivity filter of potassium channels do not rule out constricted-like conformations for C-type inactivation. Proc Natl Acad Sci U S A. 2017 10 17; 114(42):11145-11150. PMID: 28973956.
      View in: PubMed
    7. Vandenberg JI, Perozo E, Allen TW. Towards a Structural View of Drug Binding to hERG K+ Channels. Trends Pharmacol Sci. 2017 10; 38(10):899-907. PMID: 28711156.
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    8. Kratochvil HT, Maj M, Matulef K, Annen AW, Ostmeyer J, Perozo E, Roux B, Valiyaveetil FI, Zanni MT. Probing the Effects of Gating on the Ion Occupancy of the K+ Channel Selectivity Filter Using Two-Dimensional Infrared Spectroscopy. J Am Chem Soc. 2017 Jul 05; 139(26):8837-8845. PMID: 28472884.
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    9. Laguerre A, Löhr F, Henrich E, Hoffmann B, Abdul-Manan N, Connolly PJ, Perozo E, Moore JM, Bernhard F, Dötsch V. From Nanodiscs to Isotropic Bicelles: A Procedure for Solution Nuclear Magnetic Resonance Studies of Detergent-Sensitive Integral Membrane Proteins. Structure. 2016 Oct 04; 24(10):1830-1841. PMID: 27618661.
      View in: PubMed
    10. Kratochvil HT, Carr JK, Matulef K, Annen AW, Li H, Maj M, Ostmeyer J, Serrano AL, Raghuraman H, Moran SD, Skinner JL, Perozo E, Roux B, Valiyaveetil FI, Zanni MT. Instantaneous ion configurations in the K+ ion channel selectivity filter revealed by 2D IR spectroscopy. Science. 2016 09 02; 353(6303):1040-1044. PMID: 27701114.
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    11. Bavi N, Cox CD, Perozo E, Martinac B. Toward a structural blueprint for bilayer-mediated channel mechanosensitivity. Channels (Austin). 2017 Mar 04; 11(2):91-93. PMID: 27533603.
      View in: PubMed
    12. Bavi N, Cortes DM, Cox CD, Rohde PR, Liu W, Deitmer JW, Bavi O, Strop P, Hill AP, Rees D, Corry B, Perozo E, Martinac B. The role of MscL amphipathic N terminus indicates a blueprint for bilayer-mediated gating of mechanosensitive channels. Nat Commun. 2016 Jun 22; 7:11984. PMID: 27329693.
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    13. Medovoy D, Perozo E, Roux B. Multi-ion free energy landscapes underscore the microscopic mechanism of ion selectivity in the KcsA channel. Biochim Biophys Acta. 2016 Jul; 1858(7 Pt B):1722-32. PMID: 26896693.
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    14. Matthies D, Dalmas O, Borgnia MJ, Dominik PK, Merk A, Rao P, Reddy BG, Islam S, Bartesaghi A, Perozo E, Subramaniam S. Cryo-EM Structures of the Magnesium Channel CorA Reveal Symmetry Break upon Gating. Cell. 2016 Feb 11; 164(4):747-56. PMID: 26871634.
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    15. Dominik PK, Borowska MT, Dalmas O, Kim SS, Perozo E, Keenan RJ, Kossiakoff AA. Conformational Chaperones for Structural Studies of Membrane Proteins Using Antibody Phage Display with Nanodiscs. Structure. 2016 Feb 02; 24(2):300-9. PMID: 26749445.
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    16. Li Q, Shen R, Treger JS, Wanderling SS, Milewski W, Siwowska K, Bezanilla F, Perozo E. Resting state of the human proton channel dimer in a lipid bilayer. Proc Natl Acad Sci U S A. 2015 Nov 03; 112(44):E5926-35. PMID: 26443860.
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    17. van der Cruijsen EA, Koers EJ, Sauvée C, Hulse RE, Weingarth M, Ouari O, Perozo E, Tordo P, Baldus M. Biomolecular DNP-Supported NMR Spectroscopy using Site-Directed Spin Labeling. Chemistry. 2015 Sep 07; 21(37):12971-7. PMID: 26315337.
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    18. McGreevy R, Singharoy A, Li Q, Zhang J, Xu D, Perozo E, Schulten K. xMDFF: molecular dynamics flexible fitting of low-resolution X-ray structures. Acta Crystallogr D Biol Crystallogr. 2014 Sep; 70(Pt 9):2344-55. PMID: 25195748.
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    19. Hulse RE, Sachleben JR, Wen PC, Moradi M, Tajkhorshid E, Perozo E. Conformational dynamics at the inner gate of KcsA during activation. Biochemistry. 2014 Apr 29; 53(16):2557-9. PMID: 24621378.
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    20. Dalmas O, Sompornpisut P, Bezanilla F, Perozo E. Molecular mechanism of Mg2+-dependent gating in CorA. Nat Commun. 2014 Apr 02; 5:3590. PMID: 24694723.
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    21. Randich AM, Cuello LG, Wanderling SS, Perozo E. Biochemical and structural analysis of the hyperpolarization-activated K(+) channel MVP. Biochemistry. 2014 Mar 18; 53(10):1627-36. PMID: 24490868.
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    22. Dalmas O, Sandtner W, Medovoy D, Frezza L, Bezanilla F, Perozo E. A repulsion mechanism explains magnesium permeation and selectivity in CorA. Proc Natl Acad Sci U S A. 2014 Feb 25; 111(8):3002-7. PMID: 24516146.
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    23. Li Q, Wanderling S, Paduch M, Medovoy D, Singharoy A, McGreevy R, Villalba-Galea CA, Hulse RE, Roux B, Schulten K, Kossiakoff A, Perozo E. Structural mechanism of voltage-dependent gating in an isolated voltage-sensing domain. Nat Struct Mol Biol. 2014 Mar; 21(3):244-52. PMID: 24487958.
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    24. Raghuraman H, Islam SM, Mukherjee S, Roux B, Perozo E. Dynamics transitions at the outer vestibule of the KcsA potassium channel during gating. Proc Natl Acad Sci U S A. 2014 Feb 04; 111(5):1831-6. PMID: 24429344.
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    25. Li Q, Wanderling S, Sompornpisut P, Perozo E. Structural basis of lipid-driven conformational transitions in the KvAP voltage-sensing domain. Nat Struct Mol Biol. 2014 Feb; 21(2):160-6. PMID: 24413055.
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    26. Ostmeyer J, Chakrapani S, Pan AC, Perozo E, Roux B. Recovery from slow inactivation in K+ channels is controlled by water molecules. Nature. 2013 Sep 05; 501(7465):121-4. PMID: 23892782.
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    27. van der Cruijsen EA, Nand D, Weingarth M, Prokofyev A, Hornig S, Cukkemane AA, Bonvin AM, Becker S, Hulse RE, Perozo E, Pongs O, Baldus M. Importance of lipid-pore loop interface for potassium channel structure and function. Proc Natl Acad Sci U S A. 2013 Aug 06; 110(32):13008-13. PMID: 23882077.
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    28. White EA, Raghuraman H, Perozo E, Glotzer M. Binding of the CYK-4 subunit of the centralspindlin complex induces a large scale conformational change in the kinesin subunit. J Biol Chem. 2013 Jul 05; 288(27):19785-95. PMID: 23720745.
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    29. Vargas E, Yarov-Yarovoy V, Khalili-Araghi F, Catterall WA, Klein ML, Tarek M, Lindahl E, Schulten K, Perozo E, Bezanilla F, Roux B. An emerging consensus on voltage-dependent gating from computational modeling and molecular dynamics simulations. J Gen Physiol. 2012 Dec; 140(6):587-94. PMID: 23183694.
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    30. Li Q, Jogini V, Wanderling S, Cortes DM, Perozo E. Expression, purification, and reconstitution of the voltage-sensing domain from Ci-VSP. Biochemistry. 2012 Oct 16; 51(41):8132-42. PMID: 22989304.
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    31. Dalmas O, Hyde HC, Hulse RE, Perozo E. Symmetry-constrained analysis of pulsed double electron-electron resonance (DEER) spectroscopy reveals the dynamic nature of the KcsA activation gate. J Am Chem Soc. 2012 Oct 03; 134(39):16360-9. PMID: 22946877.
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    32. Raghuraman H, Cordero-Morales JF, Jogini V, Pan AC, Kollewe A, Roux B, Perozo E. Mechanism of Cd2+ coordination during slow inactivation in potassium channels. Structure. 2012 Aug 08; 20(8):1332-42. PMID: 22771214.
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    33. Torbeev VY, Raghuraman H, Hamelberg D, Tonelli M, Westler WM, Perozo E, Kent SB. Protein conformational dynamics in the mechanism of HIV-1 protease catalysis. Proc Natl Acad Sci U S A. 2011 Dec 27; 108(52):20982-7. PMID: 22158985.
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    34. Pan AC, Cuello LG, Perozo E, Roux B. Thermodynamic coupling between activation and inactivation gating in potassium channels revealed by free energy molecular dynamics simulations. J Gen Physiol. 2011 Dec; 138(6):571-80. PMID: 22124115.
      View in: PubMed
    35. Ferrer T, Cordero-Morales JF, Arias M, Ficker E, Medovoy D, Perozo E, Tristani-Firouzi M. Molecular coupling in the human ether-a-go-go-related gene-1 (hERG1) K+ channel inactivation pathway. J Biol Chem. 2011 Nov 11; 286(45):39091-9. PMID: 21908602.
      View in: PubMed
    36. Uysal S, Cuello LG, Cortes DM, Koide S, Kossiakoff AA, Perozo E. Mechanism of activation gating in the full-length KcsA K+ channel. Proc Natl Acad Sci U S A. 2011 Jul 19; 108(29):11896-9. PMID: 21730186.
      View in: PubMed
    37. Cordero-Morales JF, Jogini V, Chakrapani S, Perozo E. A multipoint hydrogen-bond network underlying KcsA C-type inactivation. Biophys J. 2011 May 18; 100(10):2387-93. PMID: 21575572.
      View in: PubMed
    38. Chakrapani S, Cordero-Morales JF, Jogini V, Pan AC, Cortes DM, Roux B, Perozo E. On the structural basis of modal gating behavior in K(+) channels. Nat Struct Mol Biol. 2011 Jan; 18(1):67-74. PMID: 21186363.
      View in: PubMed
    39. Hulse RE, Li Q, Perozo E. Up a hydrophobic creek with a short paddle. Cell. 2010 Aug 20; 142(4):515-6. PMID: 20723752.
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    40. Dalmas O, Cuello LG, Jogini V, Cortes DM, Roux B, Perozo E. Structural dynamics of the magnesium-bound conformation of CorA in a lipid bilayer. Structure. 2010 Jul 14; 18(7):868-78. PMID: 20637423.
      View in: PubMed
    41. Cuello LG, Jogini V, Cortes DM, Pan AC, Gagnon DG, Dalmas O, Cordero-Morales JF, Chakrapani S, Roux B, Perozo E. Structural basis for the coupling between activation and inactivation gates in K(+) channels. Nature. 2010 Jul 08; 466(7303):272-5. PMID: 20613845.
      View in: PubMed
    42. Cuello LG, Jogini V, Cortes DM, Perozo E. Structural mechanism of C-type inactivation in K(+) channels. Nature. 2010 Jul 08; 466(7303):203-8. PMID: 20613835.
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    43. Chakrapani S, Sompornpisut P, Intharathep P, Roux B, Perozo E. The activated state of a sodium channel voltage sensor in a membrane environment. Proc Natl Acad Sci U S A. 2010 Mar 23; 107(12):5435-40. PMID: 20207950.
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    44. Cuello LG, Jogini V, Cortes DM, Sompornpisut A, Purdy MD, Wiener MC, Perozo E. Design and characterization of a constitutively open KcsA. FEBS Lett. 2010 Mar 19; 584(6):1133-8. PMID: 20153331.
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    45. Cuello LG, Cortes DM, Jogini V, Sompornpisut A, Perozo E. A molecular mechanism for proton-dependent gating in KcsA. FEBS Lett. 2010 Mar 19; 584(6):1126-32. PMID: 20138880.
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    46. Takacs Z, Toups M, Kollewe A, Johnson E, Cuello LG, Driessens G, Biancalana M, Koide A, Ponte CG, Perozo E, Gajewski TF, Suarez-Kurtz G, Koide S, Goldstein SA. A designer ligand specific for Kv1.3 channels from a scorpion neurotoxin-based library. Proc Natl Acad Sci U S A. 2009 Dec 29; 106(52):22211-6. PMID: 20007782.
      View in: PubMed
    47. Vásquez V, Perozo E. Structural biology: A channel with a twist. Nature. 2009 Sep 03; 461(7260):47-9. PMID: 19727188.
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    48. Uysal S, Vásquez V, Tereshko V, Esaki K, Fellouse FA, Sidhu SS, Koide S, Perozo E, Kossiakoff A. Crystal structure of full-length KcsA in its closed conformation. Proc Natl Acad Sci U S A. 2009 Apr 21; 106(16):6644-9. PMID: 19346472.
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    49. Torbeev VY, Raghuraman H, Mandal K, Senapati S, Perozo E, Kent SB. Dynamics of "flap" structures in three HIV-1 protease/inhibitor complexes probed by total chemical synthesis and pulse-EPR spectroscopy. J Am Chem Soc. 2009 Jan 28; 131(3):884-5. PMID: 19117390.
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    50. Goetz BA, Perozo E, Locher KP. Distinct gate conformations of the ABC transporter BtuCD revealed by electron spin resonance spectroscopy and chemical cross-linking. FEBS Lett. 2009 Jan 22; 583(2):266-70. PMID: 19101549.
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    51. Vásquez V, Sotomayor M, Cordero-Morales J, Schulten K, Perozo E. A structural mechanism for MscS gating in lipid bilayers. Science. 2008 Aug 29; 321(5893):1210-4. PMID: 18755978.
      View in: PubMed
    52. Sompornpisut P, Roux B, Perozo E. Structural refinement of membrane proteins by restrained molecular dynamics and solvent accessibility data. Biophys J. 2008 Dec; 95(11):5349-61. PMID: 18676641.
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    53. Chakrapani S, Cuello LG, Cortes DM, Perozo E. Structural dynamics of an isolated voltage-sensor domain in a lipid bilayer. Structure. 2008 Mar; 16(3):398-409. PMID: 18334215.
      View in: PubMed
    54. Vásquez V, Sotomayor M, Cortes DM, Roux B, Schulten K, Perozo E. Three-dimensional architecture of membrane-embedded MscS in the closed conformation. J Mol Biol. 2008 Apr 18; 378(1):55-70. PMID: 18343404.
      View in: PubMed
    55. Chakrapani S, Cordero-Morales JF, Perozo E. A quantitative description of KcsA gating II: single-channel currents. J Gen Physiol. 2007 Nov; 130(5):479-96. PMID: 17938231.
      View in: PubMed
    56. Chakrapani S, Cordero-Morales JF, Perozo E. A quantitative description of KcsA gating I: macroscopic currents. J Gen Physiol. 2007 Nov; 130(5):465-78. PMID: 17938230.
      View in: PubMed
    57. Cordero-Morales JF, Jogini V, Lewis A, Vásquez V, Cortes DM, Roux B, Perozo E. Molecular driving forces determining potassium channel slow inactivation. Nat Struct Mol Biol. 2007 Nov; 14(11):1062-9. PMID: 17922012.
      View in: PubMed
    58. Hvorup RN, Goetz BA, Niederer M, Hollenstein K, Perozo E, Locher KP. Asymmetry in the structure of the ABC transporter-binding protein complex BtuCD-BtuF. Science. 2007 Sep 07; 317(5843):1387-90. PMID: 17673622.
      View in: PubMed
    59. Vásquez V, Cortes DM, Furukawa H, Perozo E. An optimized purification and reconstitution method for the MscS channel: strategies for spectroscopical analysis. Biochemistry. 2007 Jun 12; 46(23):6766-73. PMID: 17500538.
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    60. Chakrapani S, Perozo E. How to gate an ion channel: lessons from MthK. Nat Struct Mol Biol. 2007 Mar; 14(3):180-2. PMID: 17334406.
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    61. Sotomayor M, Vásquez V, Perozo E, Schulten K. Ion conduction through MscS as determined by electrophysiology and simulation. Biophys J. 2007 Feb 01; 92(3):886-902. PMID: 17114233.
      View in: PubMed
    62. Blunck R, Cordero-Morales JF, Cuello LG, Perozo E, Bezanilla F. Detection of the opening of the bundle crossing in KcsA with fluorescence lifetime spectroscopy reveals the existence of two gates for ion conduction. J Gen Physiol. 2006 Nov; 128(5):569-81. PMID: 17043150.
      View in: PubMed
    63. Cordero-Morales JF, Cuello LG, Zhao Y, Jogini V, Cortes DM, Roux B, Perozo E. Molecular determinants of gating at the potassium-channel selectivity filter. Nat Struct Mol Biol. 2006 Apr; 13(4):311-8. PMID: 16532009.
      View in: PubMed
    64. Cordero-Morales JF, Cuello LG, Perozo E. Voltage-dependent gating at the KcsA selectivity filter. Nat Struct Mol Biol. 2006 Apr; 13(4):319-22. PMID: 16532008.
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    65. Perozo E. Gating prokaryotic mechanosensitive channels. Nat Rev Mol Cell Biol. 2006 Feb; 7(2):109-19. PMID: 16493417.
      View in: PubMed
    66. Sale K, Song L, Liu YS, Perozo E, Fajer P. Explicit treatment of spin labels in modeling of distance constraints from dipolar EPR and DEER. J Am Chem Soc. 2005 Jul 06; 127(26):9334-5. PMID: 15984837.
      View in: PubMed
    67. Ptak CP, Cuello LG, Perozo E. Electrostatic interaction of a K+ channel RCK domain with charged membrane surfaces. Biochemistry. 2005 Jan 11; 44(1):62-71. PMID: 15628846.
      View in: PubMed
    68. Cuello LG, Cortes DM, Perozo E. Molecular architecture of the KvAP voltage-dependent K+ channel in a lipid bilayer. Science. 2004 Oct 15; 306(5695):491-5. PMID: 15486302.
      View in: PubMed
    69. Perozo E, Rees DC. Structure and mechanism in prokaryotic mechanosensitive channels. Curr Opin Struct Biol. 2003 Aug; 13(4):432-42. PMID: 12948773.
      View in: PubMed
    70. Bezanilla F, Perozo E. The voltage sensor and the gate in ion channels. Adv Protein Chem. 2003; 63:211-41. PMID: 12629972.
      View in: PubMed
    71. Bezanilla F, Perozo E. Structural biology. Force and voltage sensors in one structure. Science. 2002 Nov 22; 298(5598):1562-3. PMID: 12446894.
      View in: PubMed
    72. Perozo E, Kloda A, Cortes DM, Martinac B. Physical principles underlying the transduction of bilayer deformation forces during mechanosensitive channel gating. Nat Struct Biol. 2002 Sep; 9(9):696-703. PMID: 12172537.
      View in: PubMed
    73. Perozo E, Cortes DM, Sompornpisut P, Kloda A, Martinac B. Open channel structure of MscL and the gating mechanism of mechanosensitive channels. Nature. 2002 Aug 29; 418(6901):942-8. PMID: 12198539.
      View in: PubMed
    74. Li J, Xu Q, Cortes DM, Perozo E, Laskey A, Karlin A. Reactions of cysteines substituted in the amphipathic N-terminal tail of a bacterial potassium channel with hydrophilic and hydrophobic maleimides. Proc Natl Acad Sci U S A. 2002 Sep 03; 99(18):11605-10. PMID: 12189213.
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    75. Perozo E. New structural perspectives on K(+) channel gating. Structure. 2002 Aug; 10(8):1027-9. PMID: 12176380.
      View in: PubMed
    76. Perozo E, Cuello LG, Cortes DM, Liu YS, Sompornpisut P. EPR approaches to ion channel structure and function. Novartis Found Symp. 2002; 245:146-58; discussion 158-64, 165-8. PMID: 12027005.
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    77. Sompornpisut P, Liu YS, Perozo E. Calculation of rigid-body conformational changes using restraint-driven Cartesian transformations. Biophys J. 2001 Nov; 81(5):2530-46. PMID: 11606268.
      View in: PubMed
    78. Liu YS, Sompornpisut P, Perozo E. Structure of the KcsA channel intracellular gate in the open state. Nat Struct Biol. 2001 Oct; 8(10):883-7. PMID: 11573095.
      View in: PubMed
    79. Perozo E, Kloda A, Cortes DM, Martinac B. Site-directed spin-labeling analysis of reconstituted Mscl in the closed state. J Gen Physiol. 2001 Aug; 118(2):193-206. PMID: 11479346.
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    80. Cortes DM, Cuello LG, Perozo E. Molecular architecture of full-length KcsA: role of cytoplasmic domains in ion permeation and activation gating. J Gen Physiol. 2001 Feb; 117(2):165-80. PMID: 11158168.
      View in: PubMed
    81. Perozo E. Structure and packing orientation of transmembrane segments in voltage-dependent channels. Lessons from perturbation analysis. J Gen Physiol. 2000 Jan; 115(1):29-32. PMID: 10613916.
      View in: PubMed
    82. Perozo E, Cortes DM, Cuello LG. Structural rearrangements underlying K+-channel activation gating. Science. 1999 Jul 02; 285(5424):73-8. PMID: 10390363.
      View in: PubMed
    83. Perozo E. Shedding light on voltage-dependent gating. J Gen Physiol. 1998 Oct; 112(4):373-6. PMID: 9758857.
      View in: PubMed
    84. Perozo E, Cortes DM, Cuello LG. Three-dimensional architecture and gating mechanism of a K+ channel studied by EPR spectroscopy. Nat Struct Biol. 1998 Jun; 5(6):459-69. PMID: 9628484.
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    85. Cuello LG, Romero JG, Cortes DM, Perozo E. pH-dependent gating in the Streptomyces lividans K+ channel. Biochemistry. 1998 Mar 10; 37(10):3229-36. PMID: 9536962.
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    86. Tatulian SA, Cortes DM, Perozo E. Structural dynamics of the Streptomyces lividans K+ channel (SKC1): secondary structure characterization from FTIR spectroscopy. FEBS Lett. 1998 Feb 20; 423(2):205-12. PMID: 9512358.
      View in: PubMed
    87. Cortes DM, Perozo E. Structural dynamics of the Streptomyces lividans K+ channel (SKC1): oligomeric stoichiometry and stability. Biochemistry. 1997 Aug 19; 36(33):10343-52. PMID: 9254634.
      View in: PubMed
    88. Bogomolni RA, Stoeckenius W, Szundi I, Perozo E, Olson KD, Spudich JL. Removal of transducer HtrI allows electrogenic proton translocation by sensory rhodopsin I. Proc Natl Acad Sci U S A. 1994 Oct 11; 91(21):10188-92. PMID: 7937859.
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    89. Caputo C, Perozo E, Bezanilla F. Chemical modification of squid axon K+ channel -SH groups with the organic mercurial compound p-hydroxymercuriphenylsulfonic acid (PHMPS). Pflugers Arch. 1994 Oct; 428(3-4):315-22. PMID: 7816554.
      View in: PubMed
    90. Stefani E, Toro L, Perozo E, Bezanilla F. Gating of Shaker K+ channels: I. Ionic and gating currents. Biophys J. 1994 Apr; 66(4):996-1010. PMID: 8038403.
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    91. Bezanilla F, Perozo E, Stefani E. Gating of Shaker K+ channels: II. The components of gating currents and a model of channel activation. Biophys J. 1994 Apr; 66(4):1011-21. PMID: 8038375.
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    92. Santacruz-Toloza L, Perozo E, Papazian DM. Purification and reconstitution of functional Shaker K+ channels assayed with a light-driven voltage-control system. Biochemistry. 1994 Feb 15; 33(6):1295-9. PMID: 8312246.
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    93. Perozo E, Santacruz-Toloza L, Stefani E, Bezanilla F, Papazian DM. S4 mutations alter gating currents of Shaker K channels. Biophys J. 1994 Feb; 66(2 Pt 1):345-54. PMID: 8161688.
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    94. Perozo E, Hubbell WL. Voltage activation of reconstituted sodium channels: use of bacteriorhodopsin as a light-driven current source. Biochemistry. 1993 Oct 05; 32(39):10471-8. PMID: 8399193.
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    95. Perozo E, MacKinnon R, Bezanilla F, Stefani E. Gating currents from a nonconducting mutant reveal open-closed conformations in Shaker K+ channels. Neuron. 1993 Aug; 11(2):353-8. PMID: 8352943.
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    96. Perozo E, Papazian DM, Stefani E, Bezanilla F. Gating currents in Shaker K+ channels. Implications for activation and inactivation models. Biophys J. 1992 Apr; 62(1):160-8; discussion 169-71. PMID: 1600094.
      View in: PubMed
    97. Bezanilla F, Perozo E, Papazian DM, Stefani E. Molecular basis of gating charge immobilization in Shaker potassium channels. Science. 1991 Nov 01; 254(5032):679-83. PMID: 1948047.
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    98. Perozo E, Bezanilla F. Phosphorylation of K+ channels in the squid giant axon. A mechanistic analysis. J Bioenerg Biomembr. 1991 Aug; 23(4):599-613. PMID: 1917910.
      View in: PubMed
    99. Perozo E, Vandenberg CA, Jong DS, Bezanilla F. Single channel studies of the phosphorylation of K+ channels in the squid giant axon. I. Steady-state conditions. J Gen Physiol. 1991 Jul; 98(1):1-17. PMID: 1940846.
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    100. Perozo E, Jong DS, Bezanilla F. Single channel studies of the phosphorylation of K+ channels in the squid giant axon. II. Nonstationary conditions. J Gen Physiol. 1991 Jul; 98(1):19-34. PMID: 1940848.
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    101. Perozo E, Bezanilla F. Phosphorylation affects voltage gating of the delayed rectifier K+ channel by electrostatic interactions. Neuron. 1990 Nov; 5(5):685-90. PMID: 2223093.
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    102. Perozo E, Bezanilla F, Dipolo R. Modulation of K channels in dialyzed squid axons. ATP-mediated phosphorylation. J Gen Physiol. 1989 Jun; 93(6):1195-218. PMID: 2769224.
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    103. Urbina JA, Cohen BE, Perozo E, Cornivelli L. Spin-labeled amphotericin B: synthesis, characterization, biological and spectroscopic properties. Biochim Biophys Acta. 1987 Mar 12; 897(3):467-73. PMID: 3028486.
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