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Loss of PINK1 attenuates HIF-1a induction by preventing 4E-BP1-dependent switch in protein translation under hypoxia.
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Loss of PINK1 attenuates HIF-1a induction by preventing 4E-BP1-dependent switch in protein translation under hypoxia.
Loss of PINK1 attenuates HIF-1a induction by preventing 4E-BP1-dependent switch in protein translation under hypoxia. J Neurosci. 2014 Feb 19; 34(8):3079-89.
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subject areas
Adaptor Proteins, Signal Transducing
Animals
Blotting, Western
Carrier Proteins
Cell Cycle Proteins
Cell Line
Cells, Cultured
Cycloheximide
DNA, Complementary
Eukaryotic Initiation Factors
Hydrogen Peroxide
Hypoxia, Brain
Hypoxia-Inducible Factor 1, alpha Subunit
Immunohistochemistry
Luciferases
Mice
Mice, Knockout
Phosphoproteins
Phosphorylation
Plasmids
Polymerase Chain Reaction
Protein Biosynthesis
Protein Kinases
Protein Synthesis Inhibitors
RNA Cap Analogs
RNA, Small Interfering
authors with profiles
James Brorson