TNFR2 activates MLCK-dependent tight junction dysregulation to cause apoptosis-mediated barrier loss and experimental colitis.

TNFR2 activates MLCK-dependent tight junction dysregulation to cause apoptosis-mediated barrier loss and experimental colitis. Gastroenterology. 2013 Aug; 145(2):407-15.

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subject areas

Adoptive Transfer
Animals
Apoptosis
Claudin-2
Colitis
Dextran Sulfate
Disease Models, Animal
Epithelial Cells
Inflammatory Bowel Diseases
Intestinal Mucosa
Mice
Mice, Inbred C57BL
Myosin Light Chains
Myosin Type II
Myosin-Light-Chain Kinase
Permeability
Phosphorylation
Receptors, Tumor Necrosis Factor, Type I
Receptors, Tumor Necrosis Factor, Type II
Signal Transduction
Tight Junctions
Up-Regulation
Weight Loss

authors with profiles

Le Shen