Targeted CNS expression of interferon-gamma in transgenic mice leads to hypomyelination, reactive gliosis, and abnormal cerebellar development.

Targeted CNS expression of interferon-gamma in transgenic mice leads to hypomyelination, reactive gliosis, and abnormal cerebellar development. Mol Cell Neurosci. 1996 May; 7(5):354-70.

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subject areas

Animals
Blotting, Northern
Central Nervous System
Cerebellum
Demyelinating Diseases
Gene Expression
Gliosis
Histocompatibility Antigens Class I
Histocompatibility Antigens Class II
Immunohistochemistry
In Situ Hybridization
Interferon-gamma
Macrophages
Mice
Mice, Transgenic
Myelin Sheath
RNA, Messenger
Transgenes