"Crystallins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A heterogeneous family of water-soluble structural proteins found in cells of the vertebrate lens. The presence of these proteins accounts for the transparency of the lens. The family is composed of four major groups, alpha, beta, gamma, and delta, and several minor groups, which are classed on the basis of size, charge, immunological properties, and vertebrate source. Alpha, beta, and delta crystallins occur in avian and reptilian lenses, while alpha, beta, and gamma crystallins occur in all other lenses.
| Descriptor ID |
D003459
|
| MeSH Number(s) |
D12.776.306.366
|
| Concept/Terms |
Crystallins- Crystallins
- Lens Proteins
- Proteins, Lens
- Crystallin
|
Below are MeSH descriptors whose meaning is more general than "Crystallins".
Below are MeSH descriptors whose meaning is more specific than "Crystallins".
This graph shows the total number of publications written about "Crystallins" by people in this website by year, and whether "Crystallins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 2002 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Crystallins" by people in Profiles.
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A crystallin mutant cataract with mineral deposits. J Biol Chem. 2023 08; 299(8):104935.
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Connexin50D47A decreases levels of fiber cell connexins and impairs lens fiber cell differentiation. Invest Ophthalmol Vis Sci. 2013 Nov 19; 54(12):7614-22.
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Transgenic overexpression of connexin50 induces cataracts. Exp Eye Res. 2007 Mar; 84(3):513-28.
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Identification of CRYM as a candidate responsible for nonsyndromic deafness, through cDNA microarray analysis of human cochlear and vestibular tissues. Am J Hum Genet. 2003 Jan; 72(1):73-82.
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Bovine connexin44, a lens gap junction protein: molecular cloning, immunologic characterization, and functional expression. Invest Ophthalmol Vis Sci. 1994 Sep; 35(10):3747-58.
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Assignment of human gamma crystallin multigene family to chromosome 2. Somat Cell Mol Genet. 1985 Sep; 11(5):511-6.