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EP3 receptor deficiency attenuates pulmonary hypertension through suppression of Rho/TGF-ß1 signaling.
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EP3 receptor deficiency attenuates pulmonary hypertension through suppression of Rho/TGF-ß1 signaling.
EP3 receptor deficiency attenuates pulmonary hypertension through suppression of Rho/TGF-ß1 signaling. J Clin Invest. 2015 Mar 02; 125(3):1228-42.
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PubMed
subject areas
Animals
Cell Hypoxia
Cells, Cultured
Extracellular Matrix
Extracellular Matrix Proteins
Hypertension, Pulmonary
Male
Mice, Inbred C57BL
Mice, Knockout
Pulmonary Artery
Rats, Sprague-Dawley
Receptors, Prostaglandin E, EP3 Subtype
rho GTP-Binding Proteins
rhoA GTP-Binding Protein
Signal Transduction
Sulfonamides
Transforming Growth Factor beta1
Vascular Remodeling
authors with profiles
Lin Piao