"Nucleosomes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The repeating structural units of chromatin, each consisting of approximately 200 base pairs of DNA wound around a protein core. This core is composed of the histones H2A, H2B, H3, and H4.
| Descriptor ID |
D009707
|
| MeSH Number(s) |
A11.284.430.106.279.345.190.160.180.625 D12.776.664.224.550 G05.360.160.180.625
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Nucleosomes".
Below are MeSH descriptors whose meaning is more specific than "Nucleosomes".
This graph shows the total number of publications written about "Nucleosomes" by people in this website by year, and whether "Nucleosomes" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 2 | 3 |
| 2008 | 2 | 0 | 2 |
| 2009 | 1 | 1 | 2 |
| 2010 | 4 | 2 | 6 |
| 2011 | 1 | 3 | 4 |
| 2012 | 3 | 0 | 3 |
| 2013 | 1 | 1 | 2 |
| 2014 | 0 | 3 | 3 |
| 2015 | 1 | 1 | 2 |
| 2016 | 0 | 1 | 1 |
| 2017 | 2 | 0 | 2 |
| 2018 | 2 | 2 | 4 |
| 2019 | 0 | 3 | 3 |
| 2021 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
| 2023 | 2 | 0 | 2 |
| 2024 | 0 | 1 | 1 |
| 2025 | 0 | 2 | 2 |
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Below are the most recent publications written about "Nucleosomes" by people in Profiles.
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Thymic epithelial cells amplify epigenetic noise to promote immune tolerance. Nature. 2025 Oct; 646(8085):724-733.
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Transfer learning reveals sequence determinants of the quantitative response to transcription factor dosage. Cell Genom. 2025 Mar 12; 5(3):100780.
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Guiding the HBO1 complex function through the JADE subunit. Nat Struct Mol Biol. 2024 Jul; 31(7):1039-1049.
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Structural Basis of Sirtuin 6-Catalyzed Nucleosome Deacetylation. J Am Chem Soc. 2023 03 29; 145(12):6811-6822.
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Simultaneous Measurement of DNA Methylation and Nucleosome Occupancy in Single Cells Using scNOMe-Seq. Methods Mol Biol. 2023; 2611:231-247.
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Histone H2B Deacylation Selectivity: Exploring Chromatin's Dark Matter with an Engineered Sortase. J Am Chem Soc. 2022 03 02; 144(8):3360-3364.
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Decoding the protein composition of whole nucleosomes with Nuc-MS. Nat Methods. 2021 03; 18(3):303-308.
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Native internally calibrated chromatin immunoprecipitation for quantitative studies of histone post-translational modifications. Nat Protoc. 2019 12; 14(12):3275-3302.
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A Mutation in Histone H2B Represents a New Class of Oncogenic Driver. Cancer Discov. 2019 10; 9(10):1438-1451.
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A Click Chemistry Approach Reveals the Chromatin-Dependent Histone H3K36 Deacylase Nature of SIRT7. J Am Chem Soc. 2019 02 13; 141(6):2462-2473.