Macrophage-Activating Factors
"Macrophage-Activating Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Factors secreted by stimulated lymphocytes that prime macrophages to become nonspecifically cytotoxic to tumors. They also modulate the expression of macrophage cell surface Ia antigens. One MAF is INTERFERON-GAMMA. Other factors antigenically distinct from IFN-gamma have also been identified.
| Descriptor ID |
D016215
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| MeSH Number(s) |
D12.644.276.374.480.615 D12.776.467.374.480.615 D23.529.374.480.615
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Macrophage-Activating Factors".
Below are MeSH descriptors whose meaning is more specific than "Macrophage-Activating Factors".
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Below are the most recent publications written about "Macrophage-Activating Factors" by people in Profiles.
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Interleukin 2 and concanavalin A stimulate interferon-gamma production in a murine cytolytic T cell clone by different pathways. J Immunol. 1987 Dec 15; 139(12):3942-8.