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In vitro and in vivo efficacy of the novel oral proteasome inhibitor NNU546 in multiple myeloma.
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In vitro and in vivo efficacy of the novel oral proteasome inhibitor NNU546 in multiple myeloma.
In vitro and in vivo efficacy of the novel oral proteasome inhibitor NNU546 in multiple myeloma. Aging (Albany NY). 2020 11 16; 12(22):22949-22974.
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PubMed
subject areas
Administration, Intravenous
Administration, Oral
Animals
Apoptosis
Apoptosis Regulatory Proteins
Biological Availability
Bortezomib
Cell Line, Tumor
Cell Proliferation
Endoplasmic Reticulum Stress
Female
G2 Phase Cell Cycle Checkpoints
Humans
Male
Mice
Multiple Myeloma
Proteasome Inhibitors
Rats
Signal Transduction
Tumor Burden
Xenograft Model Antitumor Assays
authors with profiles
Evgeny Izumchenko