"Leucine Zippers" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
DNA-binding motifs formed from two alpha-helixes which intertwine for about eight turns into a coiled coil and then bifurcate to form Y shaped structures. Leucines occurring in heptad repeats end up on the same sides of the helixes and are adjacent to each other in the stem of the Y (the "zipper" region). The DNA-binding residues are located in the bifurcated region of the Y.
| Descriptor ID |
D016350
|
| MeSH Number(s) |
G02.111.570.820.709.275.500.520
|
| Concept/Terms |
Leucine Zippers- Leucine Zippers
- Leucine Zipper
- Zipper, Leucine
- Zippers, Leucine
|
Below are MeSH descriptors whose meaning is more general than "Leucine Zippers".
Below are MeSH descriptors whose meaning is more specific than "Leucine Zippers".
This graph shows the total number of publications written about "Leucine Zippers" by people in this website by year, and whether "Leucine Zippers" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 3 | 3 |
| 1996 | 0 | 1 | 1 |
| 1997 | 1 | 0 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "Leucine Zippers" by people in Profiles.
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Compensatory dendritic cell development mediated by BATF-IRF interactions. Nature. 2012 Oct 25; 490(7421):502-7.
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Kaposi's sarcoma-associated herpesvirus K8 protein interacts with hSNF5. J Gen Virol. 2003 Mar; 84(Pt 3):665-676.
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Engineered metal binding sites map the heterogeneous folding landscape of a coiled coil. Nat Struct Biol. 2001 Dec; 8(12):1042-7.
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Molecular analysis of SCARECROW function reveals a radial patterning mechanism common to root and shoot. Development. 2000 Feb; 127(3):595-603.
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Transcriptional repression by the Drosophila giant protein: cis element positioning provides an alternative means of interpreting an effector gradient. Development. 1999 Mar; 126(6):1201-10.
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Paramyxovirus fusion protein: characterization of the core trimer, a rod-shaped complex with helices in anti-parallel orientation. Virology. 1999 Feb 01; 254(1):147-59.
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Analysis of SCARECROW expression using a rapid system for assessing transgene expression in Arabidopsis roots. Plant J. 1997 Oct; 12(4):957-63.
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Hemorrhage activates NF-kappa B in murine lung mononuclear cells in vivo. Am J Physiol. 1996 May; 270(5 Pt 1):L729-35.
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Identification of domains in an Arabidopsis acyl carrier protein gene promoter required for maximal organ-specific expression. Plant Mol Biol. 1994 Dec; 26(6):1947-59.
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The high mobility group protein HMG I(Y) can stimulate or inhibit DNA binding of distinct transcription factor ATF-2 isoforms. Proc Natl Acad Sci U S A. 1994 Nov 22; 91(24):11318-22.