"Ribonuclease H" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ribonuclease that specifically cleaves the RNA moiety of RNA:DNA hybrids. It has been isolated from a wide variety of prokaryotic and eukaryotic organisms as well as RETROVIRUSES.
| Descriptor ID |
D016914
|
| MeSH Number(s) |
D08.811.277.352.355.350.700 D08.811.277.352.700.350.700
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Ribonuclease H".
Below are MeSH descriptors whose meaning is more specific than "Ribonuclease H".
This graph shows the total number of publications written about "Ribonuclease H" by people in this website by year, and whether "Ribonuclease H" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ribonuclease H" by people in Profiles.
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Structure of a spliceosome remodelled for exon ligation. Nature. 2017 02 16; 542(7641):377-380.
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3-Hydroxypyrimidine-2,4-dione-5-N-benzylcarboxamides Potently Inhibit HIV-1 Integrase and RNase H. J Med Chem. 2016 07 14; 59(13):6136-48.
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Thermodynamic system drift in protein evolution. PLoS Biol. 2014 Nov; 12(11):e1001994.
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A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation. Nat Struct Mol Biol. 2013 Jun; 20(6):728-34.
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Retroviral integrases and their cousins. Curr Opin Struct Biol. 1996 Feb; 6(1):76-83.
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Two DNA polymerases: HIV reverse transcriptase and the Klenow fragment of Escherichia coli DNA polymerase I. Cold Spring Harb Symp Quant Biol. 1993; 58:495-504.
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Glucocorticoid stimulates expression of corticotropin-releasing hormone gene in human placenta. Proc Natl Acad Sci U S A. 1988 Jul; 85(14):5244-8.