"Endonucleases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes that catalyze the hydrolysis of the internal bonds and thereby the formation of polynucleotides or oligonucleotides from ribo- or deoxyribonucleotide chains. EC 3.1.-.
| Descriptor ID |
D004720
|
| MeSH Number(s) |
D08.811.277.352.355
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Endonucleases".
Below are MeSH descriptors whose meaning is more specific than "Endonucleases".
This graph shows the total number of publications written about "Endonucleases" by people in this website by year, and whether "Endonucleases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 3 | 3 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 2 | 2 |
| 2015 | 1 | 1 | 2 |
| 2016 | 2 | 1 | 3 |
| 2017 | 2 | 0 | 2 |
| 2018 | 1 | 1 | 2 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Endonucleases" by people in Profiles.
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Single-arm, open label prospective trial to assess prediction of the role of ERCC1/XPF complex in the response of advanced NSCLC patients to platinum-based chemotherapy. ESMO Open. 2021 02; 6(1):100034.
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Mechanisms of improved specificity of engineered Cas9s revealed by single-molecule FRET analysis. Nat Struct Mol Biol. 2018 04; 25(4):347-354.
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Rewritable multi-event analog recording in bacterial and mammalian cells. Science. 2018 Apr 13; 360(6385).
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Multidimensional Control of Cas9 by Evolved RNA Polymerase-Based Biosensors. ACS Chem Biol. 2018 02 16; 13(2):431-437.
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Programmable transcriptional repression in mycobacteria using an orthogonal CRISPR interference platform. Nat Microbiol. 2017 Feb 06; 2:16274.
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The 5'UTR variant of ERCC5 fails to influence outcomes in ovarian and lung cancer patients undergoing treatment with platinum-based drugs. Sci Rep. 2016 12 14; 6:39217.
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Real-time observation of DNA recognition and rejection by the RNA-guided endonuclease Cas9. Nat Commun. 2016 09 14; 7:12778.
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Mobile genetic elements: in silico, in vitro, in vivo. Mol Ecol. 2016 Mar; 25(5):1027-31.
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Histone modifications predispose genome regions to breakage and translocation. Genes Dev. 2015 Jul 01; 29(13):1393-402.
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Caffeine impairs resection during DNA break repair by reducing the levels of nucleases Sae2 and Dna2. Nucleic Acids Res. 2015 Aug 18; 43(14):6889-901.