"Ketanserin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A selective serotonin receptor antagonist with weak adrenergic receptor blocking properties. The drug is effective in lowering blood pressure in essential hypertension. It also inhibits platelet aggregation. It is well tolerated and is particularly effective in older patients.
| Descriptor ID |
D007650
|
| MeSH Number(s) |
D03.383.621.365 D03.633.100.786.830.333
|
| Concept/Terms |
Ketanserin- Ketanserin
- 3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H,3H)-quinazolinedione
R-41,468- R-41,468
- R 41,468
- R41,468
- R-41468
- R 41468
- R41468
|
Below are MeSH descriptors whose meaning is more general than "Ketanserin".
Below are MeSH descriptors whose meaning is more specific than "Ketanserin".
This graph shows the total number of publications written about "Ketanserin" by people in this website by year, and whether "Ketanserin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 2 | 2 |
| 2010 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ketanserin" by people in Profiles.
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State-dependent interactions between excitatory neuromodulators in the neuronal control of breathing. J Neurosci. 2010 Jun 16; 30(24):8251-62.
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5-HT evokes sensory long-term facilitation of rodent carotid body via activation of NADPH oxidase. J Physiol. 2006 Oct 01; 576(Pt 1):289-95.
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Gasping activity in vitro: a rhythm dependent on 5-HT2A receptors. J Neurosci. 2006 Mar 08; 26(10):2623-34.
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Modulation of the hypoxic sensory response of the carotid body by 5-hydroxytryptamine: role of the 5-HT2 receptor. Respir Physiol Neurobiol. 2005 Feb 15; 145(2-3):135-42.
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Dexfenfluramine elevates systemic blood pressure by inhibiting potassium currents in vascular smooth muscle cells. J Pharmacol Exp Ther. 1999 Dec; 291(3):1143-9.
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NMDA receptor-mediated oscillatory activity in the neonatal rat spinal cord is serotonin dependent. J Neurophysiol. 1998 May; 79(5):2804-8.
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Reduction of experimental vein graft intimal hyperplasia by ketanserin. J Surg Res. 1993 Jun; 54(6):530-8.
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Alterations in serotonergic receptor expression in experimental vein grafts. J Vasc Surg. 1991 Jul; 14(1):40-7.