NADPH oxidase-derived H(2)O(2) contributes to angiotensin II-induced aldosterone synthesis in human and rat adrenal cortical cells.

NADPH oxidase-derived H(2)O(2) contributes to angiotensin II-induced aldosterone synthesis in human and rat adrenal cortical cells. Antioxid Redox Signal. 2012 Aug 01; 17(3):445-59.

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subject areas

Adrenal Cortex
Aldosterone
Angiotensin II
Angiotensin Receptor Antagonists
Animals
Antioxidants
Cell Line, Tumor
Cytochrome P-450 CYP11B2
Enzyme Inhibitors
Gene Expression
Gene Expression Regulation, Enzymologic
Humans
Hydrogen Peroxide
In Vitro Techniques
Isoenzymes
Male
Membrane Glycoproteins
Mitochondria
NADPH Oxidase 2
NADPH Oxidases
Nitric Oxide Synthase
Nuclear Receptor Subfamily 4, Group A, Member 2
Rats
Rats, Sprague-Dawley
Receptors, Angiotensin
Superoxides
Type C Phospholipases
Up-Regulation

authors with profiles

Nanduri R. Prabhakar
Gayatri Raghuraman