"HIV Integrase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzyme of the HUMAN IMMUNODEFICIENCY VIRUS that is required to integrate viral DNA into cellular DNA in the nucleus of a host cell. HIV integrase is a DNA nucleotidyltransferase encoded by the pol gene.
| Descriptor ID |
D019427
|
| MeSH Number(s) |
D08.811.739.500.667.500 D08.811.913.696.445.825.500 D12.776.964.775.375.545.500 D12.776.964.775.562.764.500 D12.776.964.970.600.850.375.545.500
|
| Concept/Terms |
HIV Integrase- HIV Integrase
- Integrase, HIV
- p31 pol Gene Product, Human Immunodeficiency Virus
- p31 Integrase Protein, Human Immunodeficiency Virus
- p31 pol Gene Product, HIV
- HIV Integration Protein
- Integration Protein, HIV
- p31 Integrase Protein, HIV
|
Below are MeSH descriptors whose meaning is more general than "HIV Integrase".
Below are MeSH descriptors whose meaning is more specific than "HIV Integrase".
This graph shows the total number of publications written about "HIV Integrase" by people in this website by year, and whether "HIV Integrase" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2016 | 1 | 1 | 2 |
| 2023 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "HIV Integrase" by people in Profiles.
-
Prevalence of HIV-1 Natural Polymorphisms and Integrase-Resistance-Associated Mutations in African Children. Viruses. 2023 02 16; 15(2).
-
The Preserved HTH-Docking Cleft of HIV-1 Integrase Is Functionally Critical. Structure. 2016 11 01; 24(11):1936-1946.
-
3-Hydroxypyrimidine-2,4-dione-5-N-benzylcarboxamides Potently Inhibit HIV-1 Integrase and RNase H. J Med Chem. 2016 07 14; 59(13):6136-48.
-
LEDGF/p75-independent HIV-1 replication demonstrates a role for HRP-2 and remains sensitive to inhibition by LEDGINs. PLoS Pathog. 2012; 8(3):e1002558.
-
Stimulation of the human RAD51 nucleofilament restricts HIV-1 integration in vitro and in infected cells. J Virol. 2012 Jan; 86(1):513-26.
-
Fusion protein system designed to provide color to aid in the expression and purification of proteins in Escherichia coli. Plasmid. 2003 Nov; 50(3):169-75.