Long Interspersed Nucleotide Elements
"Long Interspersed Nucleotide Elements" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Highly repeated sequences, 6K-8K base pairs in length, which contain RNA polymerase II promoters. They also have an open reading frame that is related to the reverse transcriptase of retroviruses but they do not contain LTRs (long terminal repeats). Copies of the LINE 1 (L1) family form about 15% of the human genome. The jockey elements of Drosophila are LINEs.
| Descriptor ID |
D020084
|
| MeSH Number(s) |
G02.111.570.080.708.330.800.400 G05.360.080.708.330.800.400 G05.360.340.024.425.800.400
|
| Concept/Terms |
Long Interspersed Nucleotide Elements- Long Interspersed Nucleotide Elements
- LINE Repeat Sequences
- LINE Repeat Sequence
- Repeat Sequence, LINE
- Repeat Sequences, LINE
- Sequence, LINE Repeat
- Sequences, LINE Repeat
- Long Interspersed DNA Sequence Elements
LINE-1 Elements- LINE-1 Elements
- Element, LINE-1
- Elements, LINE-1
- LINE 1 Elements
- LINE-1 Element
- L1 Elements
- Element, L1
- Elements, L1
- L1 Element
Jockey Elements- Jockey Elements
- Element, Jockey
- Elements, Jockey
- Jockey Element
|
Below are MeSH descriptors whose meaning is more general than "Long Interspersed Nucleotide Elements".
Below are MeSH descriptors whose meaning is more specific than "Long Interspersed Nucleotide Elements".
This graph shows the total number of publications written about "Long Interspersed Nucleotide Elements" by people in this website by year, and whether "Long Interspersed Nucleotide Elements" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 1 | 2 |
| 2014 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
| 2022 | 1 | 0 | 1 |
| 2023 | 0 | 2 | 2 |
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Below are the most recent publications written about "Long Interspersed Nucleotide Elements" by people in Profiles.
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Ultrasensitive Detection of Circulating LINE-1 ORF1p as a Specific Multicancer Biomarker. Cancer Discov. 2023 12 12; 13(12):2532-2547.
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Cancer Relevance of Circulating Antibodies Against LINE-1 Antigens in Humans. Cancer Res Commun. 2023 11 08; 3(11):2256-2267.
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FTO mediates LINE1 m6A demethylation and chromatin regulation in mESCs and mouse development. Science. 2022 05 27; 376(6596):968-973.
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Oral cedazuridine/decitabine for MDS and CMML: a phase 2 pharmacokinetic/pharmacodynamic randomized crossover study. Blood. 2020 08 06; 136(6):674-683.
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Surgical necrotizing enterocolitis in extremely premature neonates is associated with genetic variations in an intergenic region of chromosome 8. Pediatr Res. 2018 05; 83(5):943-953.
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Cell lineage analysis in human brain using endogenous retroelements. Neuron. 2015 Jan 07; 85(1):49-59.
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Epigenetic potentiation of NY-ESO-1 vaccine therapy in human ovarian cancer. Cancer Immunol Res. 2014 Jan; 2(1):37-49.
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Landscape of somatic retrotransposition in human cancers. Science. 2012 Aug 24; 337(6097):967-71.
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DNA methylation in repetitive elements and post-traumatic stress disorder: a case-control study of US military service members. Epigenomics. 2012 Feb; 4(1):29-40.
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Global DNA methylation and tumor suppressor gene promoter methylation and gastric cancer risk in an Omani Arab population. Epigenomics. 2011 Aug; 3(4):417-29.