E1A-Associated p300 Protein
"E1A-Associated p300 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the p300-CBP transcription factors that was originally identified as a binding partner for ADENOVIRUS E1A PROTEINS.
| Descriptor ID |
D050881
|
| MeSH Number(s) |
D08.811.913.050.134.415.500.575.600 D12.776.930.680.600
|
| Concept/Terms |
E1A-Associated p300 Protein- E1A-Associated p300 Protein
- E1A Associated p300 Protein
- p300 Protein, E1A-Associated
- p300 E1A-Associated Coactivator
- E1A-Associated Coactivator, p300
- p300 E1A Associated Coactivator
|
Below are MeSH descriptors whose meaning is more general than "E1A-Associated p300 Protein".
Below are MeSH descriptors whose meaning is more specific than "E1A-Associated p300 Protein".
This graph shows the total number of publications written about "E1A-Associated p300 Protein" by people in this website by year, and whether "E1A-Associated p300 Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 2 | 2 |
| 2007 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2015 | 1 | 1 | 2 |
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 1 | 2 |
| 2021 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "E1A-Associated p300 Protein" by people in Profiles.
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XP-524 is a dual-BET/EP300 inhibitor that represses oncogenic KRAS and potentiates immune checkpoint inhibition in pancreatic cancer. Proc Natl Acad Sci U S A. 2022 01 25; 119(4).
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NRF1 association with AUTS2-Polycomb mediates specific gene activation in the brain. Mol Cell. 2021 11 18; 81(22):4663-4676.e8.
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Mocetinostat for patients with previously treated, locally advanced/metastatic urothelial carcinoma and inactivating alterations of acetyltransferase genes. Cancer. 2019 02 15; 125(4):533-540.
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SIRT2 regulates oxidative stress-induced cell death through deacetylation of c-Jun NH2-terminal kinase. Cell Death Differ. 2018 09; 25(9):1638-1656.
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A novel acetyltransferase p300 inhibitor ameliorates hypertension-associated cardio-renal fibrosis. Epigenetics. 2017; 12(11):1004-1013.
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Inhibition of MUC1-C Suppresses MYC Expression and Attenuates Malignant Growth in KRAS Mutant Lung Adenocarcinomas. Cancer Res. 2016 Mar 15; 76(6):1538-48.
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Autophagy positively regulates DNA damage recognition by nucleotide excision repair. Autophagy. 2016; 12(2):357-68.
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The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia. Oncogene. 2016 Jan 21; 35(3):279-89.
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Effects of sequence variation on differential allelic transcription factor occupancy and gene expression. Genome Res. 2012 May; 22(5):860-9.
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Dynamic bookmarking of primary response genes by p300 and RNA polymerase II complexes. Proc Natl Acad Sci U S A. 2009 Nov 17; 106(46):19286-91.