Hepatocyte Nuclear Factor 3-alpha
"Hepatocyte Nuclear Factor 3-alpha" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A forkhead transcription factor that is an essential activator of GLUCAGON gene expression.
| Descriptor ID |
D051541
|
| MeSH Number(s) |
D12.776.260.262.750 D12.776.260.950.249.500 D12.776.660.352.750 D12.776.930.318.750 D12.776.930.977.249.500
|
| Concept/Terms |
Hepatocyte Nuclear Factor 3-alpha- Hepatocyte Nuclear Factor 3-alpha
- Hepatocyte Nuclear Factor 3 alpha
- HNF-3alpha Protein
- HNF 3alpha Protein
- Forkhead Box A1 Protein
- Hepatocyte Nuclear Factor 3alpha
- HNF-3A Transcription Factor
- HNF 3A Transcription Factor
- Transcription Factor, HNF-3A
- Hepatocyte-Enriched Transcription Factor HNF-3A
- Hepatocyte Enriched Transcription Factor HNF 3A
|
Below are MeSH descriptors whose meaning is more general than "Hepatocyte Nuclear Factor 3-alpha".
Below are MeSH descriptors whose meaning is more specific than "Hepatocyte Nuclear Factor 3-alpha".
This graph shows the total number of publications written about "Hepatocyte Nuclear Factor 3-alpha" by people in this website by year, and whether "Hepatocyte Nuclear Factor 3-alpha" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Hepatocyte Nuclear Factor 3-alpha" by people in Profiles.
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NSD2 is a requisite subunit of the AR/FOXA1 neo-enhanceosome in promoting prostate tumorigenesis. Nat Genet. 2024 Oct; 56(10):2132-2143.
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An in vivo functional genomics screen of nuclear receptors and their co-regulators identifies FOXA1 as an essential gene in lung tumorigenesis. Neoplasia. 2020 08; 22(8):294-310.
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The Lineage Determining Factor GRHL2 Collaborates with FOXA1 to Establish a Targetable Pathway in Endocrine Therapy-Resistant Breast Cancer. Cell Rep. 2019 10 22; 29(4):889-903.e10.
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FOXA1 potentiates lineage-specific enhancer activation through modulating TET1 expression and function. Nucleic Acids Res. 2016 09 30; 44(17):8153-64.
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Nfib Regulates Transcriptional Networks That Control the Development of Prostatic Hyperplasia. Endocrinology. 2016 Mar; 157(3):1094-109.
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FOXA1 deletion in luminal epithelium causes prostatic hyperplasia and alteration of differentiated phenotype. Lab Invest. 2014 Jul; 94(7):726-39.
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Loss of the urothelial differentiation marker FOXA1 is associated with high grade, late stage bladder cancer and increased tumor proliferation. PLoS One. 2012; 7(5):e36669.
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Nucleosome dynamics define transcriptional enhancers. Nat Genet. 2010 Apr; 42(4):343-7.
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Directed differentiation of embryonic stem cells into bladder tissue. Dev Biol. 2007 Apr 15; 304(2):556-66.
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Forkhead box A1 regulates prostate ductal morphogenesis and promotes epithelial cell maturation. Development. 2005 Aug; 132(15):3431-43.