Autophagy-Related Protein 12
"Autophagy-Related Protein 12" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A UBIQUITIN-like modifier protein that functions in AUTOPHAGOSOME formation, CYTOPLASM to VACUOLE transport, MITOPHAGY, and nucleophagy. Conjugation with ATG5 PROTEIN or ATG10 is essential for its function. The ATG12-ATG5 conjugate acts as an E3 UBIQUITIN LIGASE-like enzyme for lipid modification of ATG8 FAMILY PROTEINS and their localization to vesicle membranes.
| Descriptor ID |
D000071192
|
| MeSH Number(s) |
D12.776.094.391 D12.776.947.125
|
| Concept/Terms |
Autophagy-Related Protein 12- Autophagy-Related Protein 12
- Autophagy Related Protein 12
- ATG12 Protein
- Ubiquitin-Like Protein ATG12
- ATG12, Ubiquitin-Like Protein
- Ubiquitin Like Protein ATG12
|
Below are MeSH descriptors whose meaning is more general than "Autophagy-Related Protein 12".
Below are MeSH descriptors whose meaning is more specific than "Autophagy-Related Protein 12".
This graph shows the total number of publications written about "Autophagy-Related Protein 12" by people in this website by year, and whether "Autophagy-Related Protein 12" was a major or minor topic of these publications.
![]()
To see the data from this visualization as text,
click here.
Below are the most recent publications written about "Autophagy-Related Protein 12" by people in Profiles.
-
The parasitophorous vacuole membrane of Toxoplasma gondii is targeted for disruption by ubiquitin-like conjugation systems of autophagy. Immunity. 2014 Jun 19; 40(6):924-35.
-
Nondegradative role of Atg5-Atg12/ Atg16L1 autophagy protein complex in antiviral activity of interferon gamma. Cell Host Microbe. 2012 Apr 19; 11(4):397-409.
-
The Atg8 conjugation system is indispensable for proper development of autophagic isolation membranes in mice. Mol Biol Cell. 2008 Nov; 19(11):4762-75.