"Pyrin Domain" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A protein interaction domain of the death domain superfamily. It is characterized by a 6-helix bundle similar to those that occur in DEATH DOMAIN RECEPTORS. Pyrin domains are present in a variety of proteins, especially those that function in INFLAMMASOMES; AUTOPHAGY; and APOPTOSIS. They form homodimers or heterodimers with death domain proteins to facilitate the assembly of signaling complexes.
| Descriptor ID |
D000071196
|
| MeSH Number(s) |
G02.111.570.820.709.275.750.500.395.875
|
| Concept/Terms |
Pyrin Domain- Pyrin Domain
- Pyrin Domains
- DAPIN Domain
- DAPIN Domains
- PAAD-DAPIN-PYRIN Domain
- PAAD DAPIN PYRIN Domain
- PAAD-DAPIN-PYRIN Domains
- PYD Domain
- PYD Domains
- PADD Domain
- PADD Domains
|
Below are MeSH descriptors whose meaning is more general than "Pyrin Domain".
Below are MeSH descriptors whose meaning is more specific than "Pyrin Domain".
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