Caspase Activation and Recruitment Domain
"Caspase Activation and Recruitment Domain" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A homotypic protein interaction module of the death domain superfamily. It is composed of a bundle of six alpha-helices that is related in sequence and structure to the DEATH DOMAIN and DEATH EFFECTOR DOMAIN. The Caspase Activation and Recruitment Domain (CARD domain) typically associates with other CARD-containing proteins, forming either dimers or trimers. CARD domains may occur in isolation, or in combination with other domains in CARD signaling adaptor proteins and initiator CASPASES that function in APOPTOSIS.
| Descriptor ID |
D000071476
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| MeSH Number(s) |
G02.111.570.820.709.275.750.500.395.250
|
| Concept/Terms |
Caspase Activation and Recruitment Domain- Caspase Activation and Recruitment Domain
- Caspase Recruitment Domains
- Caspase Activation and Recruitment Domains
- CARD Domains
- Caspase Recruitment Domain
- Recruitment Domain, Caspase
- Recruitment Domains, Caspase
- CARD Domain
|
Below are MeSH descriptors whose meaning is more general than "Caspase Activation and Recruitment Domain".
Below are MeSH descriptors whose meaning is more specific than "Caspase Activation and Recruitment Domain".
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Below are the most recent publications written about "Caspase Activation and Recruitment Domain" by people in Profiles.
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Identification of a second binding site on the TRIM25 B30.2 domain. Biochem J. 2018 01 23; 475(2):429-440.