"Protein Domains" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Discrete protein structural units that may fold independently of the rest of the protein and have their own functions.
| Descriptor ID |
D000072417
|
| MeSH Number(s) |
G02.111.570.820.709.275.750 G02.111.570.820.709.610.500
|
| Concept/Terms |
Protein Domains- Protein Domains
- Peptide Domain
- Domain, Peptide
- Domains, Peptide
- Peptide Domains
- Protein Domain
- Domain, Protein
- Domains, Protein
|
Below are MeSH descriptors whose meaning is more general than "Protein Domains".
Below are MeSH descriptors whose meaning is more specific than "Protein Domains".
This graph shows the total number of publications written about "Protein Domains" by people in this website by year, and whether "Protein Domains" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 0 | 1 | 1 |
| 2016 | 0 | 20 | 20 |
| 2017 | 0 | 18 | 18 |
| 2018 | 0 | 21 | 21 |
| 2019 | 1 | 15 | 16 |
| 2020 | 1 | 13 | 14 |
| 2021 | 0 | 10 | 10 |
| 2022 | 0 | 4 | 4 |
| 2023 | 0 | 1 | 1 |
| 2024 | 1 | 5 | 6 |
| 2025 | 0 | 3 | 3 |
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Below are the most recent publications written about "Protein Domains" by people in Profiles.
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Structural basis and functional roles for Toll-like receptor binding to Latrophilin in C.?elegans development. Nat Struct Mol Biol. 2025 Sep; 32(9):1683-1696.
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Structural basis for nucleolin recognition of MYC promoter G-quadruplex. Science. 2025 04 18; 388(6744):eadr1752.
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Prognostic, biological, and structural implications of FLT3-JMD point mutations in acute myeloid leukemia: an analysis of Alliance studies. Leukemia. 2025 Mar; 39(3):623-631.
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Conformational coupling between extracellular and transmembrane domains modulates holo-adhesion GPCR function. Nat Commun. 2024 12 04; 15(1):10545.
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Cracked actin filaments as mechanosensitive receptors. Biophys J. 2024 10 01; 123(19):3283-3294.
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GS-441524-Diphosphate-Ribose Derivatives as Nanomolar Binders and Fluorescence Polarization Tracers for SARS-CoV-2 and Other Viral Macrodomains. ACS Chem Biol. 2024 05 17; 19(5):1093-1105.
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The severity of MUSK pathogenic variants is predicted by the protein domain they disrupt. HGG Adv. 2024 Jul 18; 5(3):100288.
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Guiding the HBO1 complex function through the JADE subunit. Nat Struct Mol Biol. 2024 Jul; 31(7):1039-1049.
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Structure-Guided Design and Synthesis of Pyridinone-Based Selective Bromodomain and Extra-Terminal Domain (BET)-First Bromodomain (BD1) Inhibitors. J Med Chem. 2024 02 22; 67(4):2712-2731.
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Pervasive, conserved secondary structure in highly charged protein regions. PLoS Comput Biol. 2023 Oct; 19(10):e1011565.