"beta-Arrestins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Non-visual system arrestins that negatively regulate G-PROTEIN-COUPLED RECEPTORS (GPCRs) and may also function independently of GPCR signaling. They bind and recruit many different signaling factors, including MITOGEN-ACTIVATED PROTEIN KINASES; SRC-FAMILY-KINASES; and FILAMIN to GPCRs and may recognize different phosphorylation states of the receptors to determine the specificity of the cellular response to signaling.
| Descriptor ID |
D000071557
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| MeSH Number(s) |
D12.644.360.024.098.525 D12.776.157.057.005.525 D12.776.476.024.104.525 D12.776.543.090.525
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "beta-Arrestins".
Below are MeSH descriptors whose meaning is more specific than "beta-Arrestins".
This graph shows the total number of publications written about "beta-Arrestins" by people in this website by year, and whether "beta-Arrestins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 2 | 2 |
| 2015 | 0 | 3 | 3 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "beta-Arrestins" by people in Profiles.
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Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias. Sci Adv. 2022 07 15; 8(28):eabn8063.
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Regulation of cellular oxidative stress and apoptosis by G protein-coupled receptor kinase-2; The role of NADPH oxidase 4. Cell Signal. 2016 Mar; 28(3):190-203.
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Regulation of mitochondrial oxidative stress by ß-arrestins in cultured human cardiac fibroblasts. Dis Model Mech. 2015 Dec; 8(12):1579-89.
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Effects of small platform catheter-based left ventricular assist device support on regional myocardial signal transduction. J Thorac Cardiovasc Surg. 2015 Nov; 150(5):1332-41.
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ß-Arrestins regulate human cardiac fibroblast transformation and collagen synthesis in adverse ventricular remodeling. J Mol Cell Cardiol. 2014 Nov; 76:73-83.
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Visualization of arrestin recruitment by a G-protein-coupled receptor. Nature. 2014 08 14; 512(7513):218-222.
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Structure of active ß-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide. Nature. 2013 May 02; 497(7447):137-41.
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Molecular components of tolerance to opiates in single hippocampal neurons. Mol Pharmacol. 2002 Jan; 61(1):55-64.