"Katanin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An AAA ATPase consisting of the 60 kDa ATPase subunit (p60 subunit A1) which severs MICROTUBULES, and an 80 kDa accessory protein (p80 subunit B1), which targets the enzyme to the CENTROSOME. It releases microtubules from the mitotic SPINDLE POLES to allow depolymerization and poleward motion of chromosomes. It is also a regulator of microtubule dynamics in NEURONAL OUTGROWTH.
| Descriptor ID |
D000074201
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| MeSH Number(s) |
D08.811.277.040.013.500.250 D08.811.277.040.025.024.250 D12.776.157.025.750.250 D12.776.220.600.450.325 D12.776.631.560.338
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Katanin".
Below are MeSH descriptors whose meaning is more specific than "Katanin".
This graph shows the total number of publications written about "Katanin" by people in this website by year, and whether "Katanin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Katanin" by people in Profiles.
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Mutations in KATNB1 cause complex cerebral malformations by disrupting asymmetrically dividing neural progenitors. Neuron. 2014 Dec 17; 84(6):1226-39.