"Stathmin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitous phosphoprotein that serves as an intracellular substrate for a variety of SIGNAL TRANSDUCTION PATHWAYS. PHOSPHORYLATION of stathmin occurs during CELL CYCLE progression, and stathmin functions as a microtubule-destabilizing protein that promotes MICROTUBULE depolymerization during INTERPHASE and late MITOSIS. Stathmin is expressed at very high levels in a variety of human CANCERS.
Descriptor ID |
D050777
|
MeSH Number(s) |
D12.776.220.600.450.480 D12.776.624.664.700.957 D12.776.744.772
|
Concept/Terms |
Stathmin- Stathmin
- Leukemia-Associated Phosphoprotein p18
- Leukemia Associated Phosphoprotein p18
- p18, Leukemia-Associated Phosphoprotein
- Metablastin
- Prosolin
- Op18 Phosphoprotein
- Phosphoprotein, Op18
- Phosphoprotein p18
- p18, Phosphoprotein
- Phosphoprotein p19
- p19, Phosphoprotein
- Lap18 Protein
- Oncoprotein 18
|
Below are MeSH descriptors whose meaning is more general than "Stathmin".
Below are MeSH descriptors whose meaning is more specific than "Stathmin".
This graph shows the total number of publications written about "Stathmin" by people in this website by year, and whether "Stathmin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
---|
2006 | 0 | 1 | 1 |
2009 | 0 | 1 | 1 |
2017 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Stathmin" by people in Profiles.
-
High stathmin expression is a marker for poor clinical outcome in endometrial cancer: An NRG oncology group/gynecologic oncology group study. Gynecol Oncol. 2017 08; 146(2):247-253.
-
Role of microtubules in attenuation of PepG-induced vascular endothelial dysfunction by atrial natriuretic peptide. Biochim Biophys Acta. 2015 Jan; 1852(1):104-19.
-
Microtubule dynamics control HGF-induced lung endothelial barrier enhancement. PLoS One. 2014; 9(9):e105912.
-
Novel role of stathmin in microtubule-dependent control of endothelial permeability. FASEB J. 2012 Sep; 26(9):3862-74.
-
Integrated genomic profiling of endometrial carcinoma associates aggressive tumors with indicators of PI3 kinase activation. Proc Natl Acad Sci U S A. 2009 Mar 24; 106(12):4834-9.
-
Overexpression of peptidyl-prolyl isomerase-like 1 is associated with the growth of colon cancer cells. Clin Cancer Res. 2006 Jan 01; 12(1):70-6.