"Zinc Finger Protein Gli2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transcriptional activator that contains five adjacent CYS2-HIS2 ZINC FINGERS. It functions in the hedgehog signaling pathway and is required for normal embryonic development. Mutations in the GLI2 gene are associated with type 9 HOLOPROSENCEPHALY and type 2 PALLISTER-HALL SYNDROME.
| Descriptor ID |
D000075746
|
| MeSH Number(s) |
D12.776.260.755.925 D12.776.930.900.850
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Zinc Finger Protein Gli2".
Below are MeSH descriptors whose meaning is more specific than "Zinc Finger Protein Gli2".
This graph shows the total number of publications written about "Zinc Finger Protein Gli2" by people in this website by year, and whether "Zinc Finger Protein Gli2" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Zinc Finger Protein Gli2" by people in Profiles.
-
Comparative genomic analysis of human GLI2 locus using slowly evolving fish revealed the ancestral gnathostome set of early developmental enhancers. Dev Dyn. 2021 05; 250(5):669-683.
-
Sonic hedgehog signaling induces vascular smooth muscle cell proliferation via induction of the G1 cyclin-retinoblastoma axis. Arterioscler Thromb Vasc Biol. 2010 Sep; 30(9):1787-94.