Transcriptional Regulator ERG
"Transcriptional Regulator ERG" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A trans-activator and member of the erythroblast transformation-specific family of transcriptions factors that contain a characteristic ETS MOTIF. It is required for PLATELET CELL ADHESION to the subendothelium and associates with CHIMERIC ONCOGENE PROTEINS in PROSTATE CANCER; EWING'S SARCOMA; and ACUTE MYELOID LEUKEMIA.
| Descriptor ID |
D000071230
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| MeSH Number(s) |
D12.776.260.755.100 D12.776.930.900.625
|
| Concept/Terms |
Transcriptional Regulator ERG- Transcriptional Regulator ERG
- Transforming Protein ERG
- V-Ets Avian Erythroblastosis Virus E26 Oncogene Homolog Protein
- V Ets Avian Erythroblastosis Virus E26 Oncogene Homolog Protein
- V-Ets Avian Erythroblastosis Virus E26 Oncogene Related Protein
- V Ets Avian Erythroblastosis Virus E26 Oncogene Related Protein
|
Below are MeSH descriptors whose meaning is more general than "Transcriptional Regulator ERG".
Below are MeSH descriptors whose meaning is more specific than "Transcriptional Regulator ERG".
This graph shows the total number of publications written about "Transcriptional Regulator ERG" by people in this website by year, and whether "Transcriptional Regulator ERG" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2003 | 0 | 2 | 2 |
| 2005 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 3 | 3 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 0 | 2 | 2 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Transcriptional Regulator ERG" by people in Profiles.
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Germ line ERG haploinsufficiency defines a new syndrome with cytopenia and hematological malignancy predisposition. Blood. 2024 10 24; 144(17):1765-1780.
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Deregulation of DUX4 and ERG in acute lymphoblastic leukemia. Nat Genet. 2016 12; 48(12):1481-1489.
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The ubiquitin ligase TRIM25 targets ERG for degradation in prostate cancer. Oncotarget. 2016 Oct 04; 7(40):64921-64931.
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Active surveillance monitoring: the role of novel biomarkers and imaging. Asian J Androl. 2015 Nov-Dec; 17(6):882-4; discussion 883.
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Ablation of the oncogenic transcription factor ERG by deubiquitinase inhibition in prostate cancer. Proc Natl Acad Sci U S A. 2014 Mar 18; 111(11):4251-6.
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BAALC and ERG expression levels are associated with outcome and distinct gene and microRNA expression profiles in older patients with de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study. Blood. 2010 Dec 16; 116(25):5660-9.
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Prognostic importance of MN1 transcript levels, and biologic insights from MN1-associated gene and microRNA expression signatures in cytogenetically normal acute myeloid leukemia: a cancer and leukemia group B study. J Clin Oncol. 2009 Jul 01; 27(19):3198-204.
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Prognostic significance of, and gene and microRNA expression signatures associated with, CEBPA mutations in cytogenetically normal acute myeloid leukemia with high-risk molecular features: a Cancer and Leukemia Group B Study. J Clin Oncol. 2008 Nov 01; 26(31):5078-87.
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The role of SPINK1 in ETS rearrangement-negative prostate cancers. Cancer Cell. 2008 Jun; 13(6):519-28.
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MicroRNA expression in cytogenetically normal acute myeloid leukemia. N Engl J Med. 2008 May 01; 358(18):1919-28.