"Ivermectin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mixture of mostly avermectin H2B1a (RN 71827-03-7) with some avermectin H2B1b (RN 70209-81-3), which are macrolides from STREPTOMYCES avermitilis. It binds glutamate-gated chloride channel to cause increased permeability and hyperpolarization of nerve and muscle cells. It also interacts with other CHLORIDE CHANNELS. It is a broad spectrum antiparasitic that is active against microfilariae of ONCHOCERCA VOLVULUS but not the adult form.
| Descriptor ID |
D007559
|
| MeSH Number(s) |
D02.540.576.500.997
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Ivermectin".
Below are MeSH descriptors whose meaning is more specific than "Ivermectin".
This graph shows the total number of publications written about "Ivermectin" by people in this website by year, and whether "Ivermectin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2022 | 1 | 1 | 2 |
| 2023 | 0 | 2 | 2 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ivermectin" by people in Profiles.
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Favorable Antiviral Effect of Metformin on SARS-CoV-2 Viral Load in a Randomized, Placebo-Controlled Clinical Trial of COVID-19. Clin Infect Dis. 2024 Aug 16; 79(2):354-363.
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Outpatient treatment of COVID-19 and incidence of post-COVID-19 condition over 10 months (COVID-OUT): a multicentre, randomised, quadruple-blind, parallel-group, phase 3 trial. Lancet Infect Dis. 2023 10; 23(10):1119-1129.
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Conformational transitions and allosteric modulation in a heteromeric glycine receptor. Nat Commun. 2023 03 13; 14(1):1363.
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Randomized Trial of Metformin, Ivermectin, and Fluvoxamine for Covid-19. N Engl J Med. 2022 08 18; 387(7):599-610.
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An unusual case of gastric outlet obstruction and melena. Clin J Gastroenterol. 2022 Apr; 15(2):374-380.
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Ivermectin lipid-based nanocarriers as novel formulations against head lice. Parasitol Res. 2017 Aug; 116(8):2111-2117.
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Multiorgan Dysfunction Syndrome from Strongyloides stercoralis Hyperinfection in a Patient with Human T-Cell Lymphotropic Virus-1 Coinfection After Initiation of Ivermectin Treatment. Am J Trop Med Hyg. 2016 Oct 05; 95(4):864-867.
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Ivermectin-loaded lipid nanocapsules: toward the development of a new antiparasitic delivery system for veterinary applications. Parasitol Res. 2016 May; 115(5):1945-53.
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Dynamic membrane depolarization is an early regulator of ependymoglial cell response to spinal cord injury in axolotl. Dev Biol. 2015 Dec 01; 408(1):14-25.
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Cross-fostering in combination with ivermectin therapy: a method to eradicate murine fur mites. Contemp Top Lab Anim Sci. 2005 Jul; 44(4):12-6.