"Ubiquitination" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The act of ligating UBIQUITINS to PROTEINS to form ubiquitin-protein ligase complexes to label proteins for transport to the PROTEASOME ENDOPEPTIDASE COMPLEX where proteolysis occurs.
| Descriptor ID |
D054875
|
| MeSH Number(s) |
G02.111.660.871.790.600.925 G02.111.691.600.775 G03.734.871.790.600.831 G05.308.670.600.831
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Ubiquitination".
Below are MeSH descriptors whose meaning is more specific than "Ubiquitination".
This graph shows the total number of publications written about "Ubiquitination" by people in this website by year, and whether "Ubiquitination" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 2 | 2 |
| 2009 | 1 | 5 | 6 |
| 2010 | 2 | 2 | 4 |
| 2011 | 2 | 5 | 7 |
| 2012 | 0 | 6 | 6 |
| 2013 | 1 | 3 | 4 |
| 2014 | 0 | 5 | 5 |
| 2015 | 1 | 3 | 4 |
| 2016 | 0 | 5 | 5 |
| 2017 | 1 | 2 | 3 |
| 2018 | 0 | 3 | 3 |
| 2019 | 1 | 0 | 1 |
| 2020 | 0 | 4 | 4 |
| 2021 | 1 | 3 | 4 |
| 2022 | 0 | 1 | 1 |
| 2024 | 0 | 2 | 2 |
| 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ubiquitination" by people in Profiles.
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SIRT2-mediated ACSS2 K271 deacetylation suppresses lipogenesis under nutrient stress. Elife. 2025 May 07; 13.
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Targeting DTX2/UFD1-mediated FTO degradation to regulate antitumor immunity. Proc Natl Acad Sci U S A. 2024 Dec 17; 121(51):e2407910121.
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RNA m5C oxidation by TET2 regulates chromatin state and leukaemogenesis. Nature. 2024 Oct; 634(8035):986-994.
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The E3 ligase TRIM1 ubiquitinates LRRK2 and controls its localization, degradation, and toxicity. J Cell Biol. 2022 04 04; 221(4).
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HRD1-mediated METTL14 degradation regulates m6A mRNA modification to suppress ER proteotoxic liver disease. Mol Cell. 2021 12 16; 81(24):5052-5065.e6.
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Structural insights into Ubr1-mediated N-degron polyubiquitination. Nature. 2021 12; 600(7888):334-338.
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K29-linked ubiquitin signaling regulates proteotoxic stress response and cell cycle. Nat Chem Biol. 2021 08; 17(8):896-905.
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Negative feedback couples Hippo pathway activation with Kibra degradation independent of Yorkie-mediated transcription. Elife. 2021 02 08; 10.
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p50 mono-ubiquitination and interaction with BARD1 regulates cell cycle progression and maintains genome stability. Nat Commun. 2020 10 06; 11(1):5007.
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TiPARP forms nuclear condensates to degrade HIF-1a and suppress tumorigenesis. Proc Natl Acad Sci U S A. 2020 06 16; 117(24):13447-13456.