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A novel hypothesis for the binding mode of HERG channel blockers.
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A novel hypothesis for the binding mode of HERG channel blockers.
A novel hypothesis for the binding mode of HERG channel blockers. Biochem Biophys Res Commun. 2006 May 26; 344(1):72-8.
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PubMed
subject areas
Computer Simulation
Dose-Response Relationship, Drug
ERG1 Potassium Channel
Ether-A-Go-Go Potassium Channels
Humans
Hydrogen Bonding
Hydrophobic and Hydrophilic Interactions
Inhibitory Concentration 50
Models, Molecular
Potassium Channel Blockers
Protein Conformation
Structure-Activity Relationship
authors with profiles
Sunhwan Jo