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Dub3 inhibition suppresses breast cancer invasion and metastasis by promoting Snail1 degradation.
Force-dependent intercellular adhesion strengthening underlies asymmetric adherens junction contraction.
Monobromobimane occupies a distinct xenobiotic substrate site in glutathione S-transferase pi.
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Dub3 inhibition suppresses breast cancer invasion and metastasis by promoting Snail1 degradation.
Dub3 inhibition suppresses breast cancer invasion and metastasis by promoting Snail1 degradation. Nat Commun. 2017 02 15; 8:14228.
View in:
PubMed
subject areas
Animals
Breast Neoplasms
Cell Line, Tumor
Cell Movement
Down-Regulation
Endopeptidases
Epithelial-Mesenchymal Transition
Female
Gene Expression Regulation, Neoplastic
Gene Knockdown Techniques
HEK293 Cells
Humans
Interleukin-6
Mice, SCID
Neoplasm Invasiveness
Neoplasm Metastasis
Neoplastic Stem Cells
Protein Binding
Protein Stability
Protein Transport
Proteolysis
Snail Family Transcription Factors
Ubiquitination
authors with profiles
Bin Zhou