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Hif-1a and Hif-2a synergize to suppress AML development but are dispensable for disease maintenance.
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Hif-1a and Hif-2a synergize to suppress AML development but are dispensable for disease maintenance.
Hif-1a and Hif-2a synergize to suppress AML development but are dispensable for disease maintenance. J Exp Med. 2015 Dec 14; 212(13):2223-34.
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PubMed
subject areas
Animals
Base Sequence
Basic Helix-Loop-Helix Transcription Factors
Cell Hypoxia
Cell Line, Tumor
Cell Proliferation
Cell Survival
CRISPR-Cas Systems
Disease Models, Animal
Disease Progression
Gene Deletion
Gene Expression Profiling
Gene Expression Regulation, Leukemic
Homeodomain Proteins
Humans
Hypoxia-Inducible Factor 1, alpha Subunit
Leukemia, Myeloid, Acute
Mice
Molecular Sequence Data
Myeloid Ecotropic Viral Integration Site 1 Protein
Neoplasm Proteins
Neoplastic Stem Cells
authors with profiles
Milica Vukovic