Item Type | Name |
Concept
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Hypoxia
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Concept
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Hypoxia-Inducible Factor 1, alpha Subunit
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Concept
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Cell Hypoxia
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Concept
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Fetal Hypoxia
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Academic Article
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Differential distribution of electrophysiologically distinct myocytes in conduit and resistance arteries determines their response to nitric oxide and hypoxia.
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Academic Article
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Chronic infusion of nitric oxide in experimental pulmonary hypertension: pulmonary pressure-flow analysis.
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Academic Article
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Diversity of response in vascular smooth muscle cells to changes in oxygen tension.
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Academic Article
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Oxygen causes fetal pulmonary vasodilation through activation of a calcium-dependent potassium channel.
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Academic Article
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Acute hypoxic pulmonary vasoconstriction: a model of oxygen sensing.
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Academic Article
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The somatostatin analog angiopeptin does not reduce chronic hypoxic pulmonary hypertension in rats.
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Academic Article
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Alterations in a redox oxygen sensing mechanism in chronic hypoxia.
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Academic Article
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Molecular identification of the role of voltage-gated K+ channels, Kv1.5 and Kv2.1, in hypoxic pulmonary vasoconstriction and control of resting membrane potential in rat pulmonary artery myocytes.
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Academic Article
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Pulmonary vasoconstriction, oxygen sensing, and the role of ion channels: Thomas A. Neff lecture.
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Academic Article
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A maturational shift in pulmonary K+ channels, from Ca2+ sensitive to voltage dependent.
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Academic Article
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Impairment of hypoxic pulmonary vasoconstriction in mice lacking the voltage-gated potassium channel Kv1.5.
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Academic Article
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Nitric oxide deficiency in fenfluramine- and dexfenfluramine-induced pulmonary hypertension.
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Academic Article
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Direct role for potassium channel inhibition in hypoxic pulmonary vasoconstriction.
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Academic Article
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Dichloroacetate, a metabolic modulator, prevents and reverses chronic hypoxic pulmonary hypertension in rats: role of increased expression and activity of voltage-gated potassium channels.
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Academic Article
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O2 sensing is preserved in mice lacking the gp91 phox subunit of NADPH oxidase.
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Academic Article
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Molecular identification of O2 sensors and O2-sensitive potassium channels in the pulmonary circulation.
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Academic Article
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Voltage-gated potassium channels in human ductus arteriosus.
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Academic Article
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The mechanism(s) of hypoxic pulmonary vasoconstriction: potassium channels, redox O(2) sensors, and controversies.
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Academic Article
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In vivo gene transfer of the O2-sensitive potassium channel Kv1.5 reduces pulmonary hypertension and restores hypoxic pulmonary vasoconstriction in chronically hypoxic rats.
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Academic Article
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Hypoxic fetoplacental vasoconstriction in humans is mediated by potassium channel inhibition.
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Academic Article
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Acute oxygen-sensing mechanisms.
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Academic Article
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An abnormal mitochondrial-hypoxia inducible factor-1alpha-Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats: similarities to human pulmonary arterial hypertension.
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Academic Article
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The role of k+ channels in determining pulmonary vascular tone, oxygen sensing, cell proliferation, and apoptosis: implications in hypoxic pulmonary vasoconstriction and pulmonary arterial hypertension.
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Academic Article
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Potassium channel diversity in the pulmonary arteries and pulmonary veins: implications for regulation of the pulmonary vasculature in health and during pulmonary hypertension.
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Academic Article
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Hypoxic pulmonary vasoconstriction: redox regulation of O2-sensitive K+ channels by a mitochondrial O2-sensor in resistance artery smooth muscle cells.
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Academic Article
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Preferential expression and function of voltage-gated, O2-sensitive K+ channels in resistance pulmonary arteries explains regional heterogeneity in hypoxic pulmonary vasoconstriction: ionic diversity in smooth muscle cells.
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Academic Article
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ZK 36-374, a stable analog of prostacyclin, prevents acute hypoxic pulmonary hypertension in the dog.
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Academic Article
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Blunted hypoxic pulmonary vasoconstriction in experimental neonatal chronic lung disease.
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Academic Article
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Counterpoint: Hypoxic pulmonary vasoconstriction is not mediated by increased production of reactive oxygen species.
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Academic Article
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The role of redox changes in oxygen sensing.
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Academic Article
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Hypoxic pulmonary vasoconstriction is unaltered by creatine depletion induced by dietary beta-guanidino propionic acid.
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Academic Article
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The effects of substance P on the preconstricted pulmonary vasculature of the anesthetized dog.
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Academic Article
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Chronic EDRF inhibition and hypoxia: effects on pulmonary circulation and systemic blood pressure.
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Academic Article
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Hypoxia potentiates nitric oxide synthesis and transiently increases cytosolic calcium levels in pulmonary artery endothelial cells.
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Academic Article
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Hypoxic pulmonary vasoconstriction is enhanced by inhibition of the synthesis of an endothelium derived relaxing factor.
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Academic Article
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Dynamin-related protein 1-mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary hypertension.
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Academic Article
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Comparison of the hemodynamic effects of nitric oxide and endothelium-dependent vasodilators in intact lungs.
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Academic Article
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Increased endothelium-derived NO in hypertensive pulmonary circulation of chronically hypoxic rats.
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Academic Article
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Effect of graded hypoxia on the induction and function of inducible nitric oxide synthase in rat mesangial cells.
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Academic Article
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Dithionite increases radical formation and decreases vasoconstriction in the lung. Evidence that dithionite does not mimic alveolar hypoxia.
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Academic Article
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Comparative effects of nisoldipine, nifedipine and bepridil on experimental pulmonary hypertension.
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Academic Article
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Chronic hypoxic pulmonary hypertension. Is thrombin involved?
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Academic Article
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Diversity of phenotype and function of vascular smooth muscle cells.
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Academic Article
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Effect of dietary fish oil on lung lipid profile and hypoxic pulmonary hypertension.
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Academic Article
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The mechanism of acute hypoxic pulmonary vasoconstriction: the tale of two channels.
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Academic Article
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Diversity in mitochondrial function explains differences in vascular oxygen sensing.
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Academic Article
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O2 sensing in the human ductus arteriosus: regulation of voltage-gated K+ channels in smooth muscle cells by a mitochondrial redox sensor.
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Academic Article
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Hypoxic pulmonary vasoconstriction.
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Academic Article
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Mitochondrial metabolism, redox signaling, and fusion: a mitochondria-ROS-HIF-1alpha-Kv1.5 O2-sensing pathway at the intersection of pulmonary hypertension and cancer.
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Academic Article
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A proposed mitochondrial-metabolic mechanism for initiation and maintenance of pulmonary arterial hypertension in fawn-hooded rats: the Warburg model of pulmonary arterial hypertension.
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Academic Article
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Cardiac glutaminolysis: a maladaptive cancer metabolism pathway in the right ventricle in pulmonary hypertension.
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Academic Article
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Emerging concepts in the molecular basis of pulmonary arterial hypertension: part I: metabolic plasticity and mitochondrial dynamics in the pulmonary circulation and right ventricle in pulmonary arterial hypertension.
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Academic Article
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Hypoxic Pulmonary Vasoconstriction: From Molecular Mechanisms to Medicine.
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Academic Article
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Increasing Incidence and Prevalence of World Health Organization Groups 1 to 4 Pulmonary Hypertension: A Population-Based Cohort Study in Ontario, Canada.
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Academic Article
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Ndufs2, a Core Subunit of Mitochondrial Complex I, Is Essential for Acute Oxygen-Sensing and Hypoxic Pulmonary Vasoconstriction.
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Academic Article
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Response by Dunham-Snary and Archer to Letter Regarding Article, "Ndufs2, a Core Subunit of Mitochondrial Complex I, Is Essential for Acute Oxygen-Sensing and Hypoxic Pulmonary Vasoconstriction".
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Academic Article
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Epigenetic Metabolic Reprogramming of Right Ventricular Fibroblasts in Pulmonary Arterial Hypertension: A Pyruvate Dehydrogenase Kinase-Dependent Shift in Mitochondrial Metabolism Promotes Right Ventricular Fibrosis.
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Academic Article
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Differentiating COVID-19 Pneumonia From Acute Respiratory Distress Syndrome and High Altitude Pulmonary Edema: Therapeutic Implications.
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Academic Article
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SARS-CoV-2 mitochondriopathy in COVID-19 pneumonia exacerbates hypoxemia.
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Grant
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Impaired mitochondrial fusion in pulmonary arterial hypertension
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Grant
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The Role of DRP-1 and Mitochondrial Fission in Pulmonary Arterial Hypertension
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