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Archer, Stephen
One or more keywords matched the following items that are connected to Archer, Stephen
Item TypeName
Concept Rats, Nude
Concept Rats, Sprague-Dawley
Concept Rats, Wistar
Concept Rats, Inbred Strains
Concept Rats
Concept Rats, Mutant Strains
Academic Article Opposing effects of oxidants and antioxidants on K+ channel activity and tone in rat vascular tissue.
Academic Article Postischemic oxygen radical production varies with duration of ischemia.
Academic Article Differential distribution of electrophysiologically distinct myocytes in conduit and resistance arteries determines their response to nitric oxide and hypoxia.
Academic Article Nebulized nitric oxide/nucleophile adduct reduces chronic pulmonary hypertension.
Academic Article Chronic infusion of nitric oxide in experimental pulmonary hypertension: pulmonary pressure-flow analysis.
Academic Article Diversity of response in vascular smooth muscle cells to changes in oxygen tension.
Academic Article Activation of the cGMP-dependent protein kinase mimics the stimulatory effect of nitric oxide and cGMP on calcium-gated potassium channels.
Academic Article The somatostatin analog angiopeptin does not reduce chronic hypoxic pulmonary hypertension in rats.
Academic Article Utility of a nitric oxide electrode for monitoring the administration of nitric oxide in biologic systems.
Academic Article Effects of fluoxetine, phentermine, and venlafaxine on pulmonary arterial pressure and electrophysiology.
Academic Article Alterations in a redox oxygen sensing mechanism in chronic hypoxia.
Academic Article Molecular identification of the role of voltage-gated K+ channels, Kv1.5 and Kv2.1, in hypoxic pulmonary vasoconstriction and control of resting membrane potential in rat pulmonary artery myocytes.
Academic Article Direct role for potassium channel inhibition in hypoxic pulmonary vasoconstriction.
Academic Article Dexfenfluramine increases pulmonary artery smooth muscle intracellular Ca2+, independent of membrane potential.
Academic Article Vitamin A decreases the incidence and severity of nitrofen-induced congenital diaphragmatic hernia in rats.
Academic Article Dexfenfluramine elevates systemic blood pressure by inhibiting potassium currents in vascular smooth muscle cells.
Academic Article Dichloroacetate, a metabolic modulator, prevents and reverses chronic hypoxic pulmonary hypertension in rats: role of increased expression and activity of voltage-gated potassium channels.
Academic Article Gene transfer and metabolic modulators as new therapies for pulmonary hypertension. Increasing expression and activity of potassium channels in rat and human models.
Academic Article In vivo gene transfer of the O2-sensitive potassium channel Kv1.5 reduces pulmonary hypertension and restores hypoxic pulmonary vasoconstriction in chronically hypoxic rats.
Academic Article The neurovascular mechanism of clitoral erection: nitric oxide and cGMP-stimulated activation of BKCa channels.
Academic Article Measurement of endothelial cytosolic calcium concentration and nitric oxide production reveals discrete mechanisms of endothelium-dependent pulmonary vasodilatation.
Academic Article Vascular endothelial growth factor gene therapy increases survival, promotes lung angiogenesis, and prevents alveolar damage in hyperoxia-induced lung injury: evidence that angiogenesis participates in alveolarization.
Academic Article The NO - K+ channel axis in pulmonary arterial hypertension. Activation by experimental oral therapies.
Academic Article An abnormal mitochondrial-hypoxia inducible factor-1alpha-Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats: similarities to human pulmonary arterial hypertension.
Academic Article Overexpression of human bone morphogenetic protein receptor 2 does not ameliorate monocrotaline pulmonary arterial hypertension.
Academic Article Enhanced chemiluminescence as a measure of oxygen-derived free radical generation during ischemia and reperfusion.
Academic Article The nuclear factor of activated T cells in pulmonary arterial hypertension can be therapeutically targeted.
Academic Article Preferential expression and function of voltage-gated, O2-sensitive K+ channels in resistance pulmonary arteries explains regional heterogeneity in hypoxic pulmonary vasoconstriction: ionic diversity in smooth muscle cells.
Academic Article Oxygen-sensitive Kv channel gene transfer confers oxygen responsiveness to preterm rabbit and remodeled human ductus arteriosus: implications for infants with patent ductus arteriosus.
Academic Article Blunted hypoxic pulmonary vasoconstriction in experimental neonatal chronic lung disease.
Academic Article The inhibition of pyruvate dehydrogenase kinase improves impaired cardiac function and electrical remodeling in two models of right ventricular hypertrophy: resuscitating the hibernating right ventricle.
Academic Article Detection of activated O2 species in vitro and in rat lungs by chemiluminescence.
Academic Article Validation of high-resolution echocardiography and magnetic resonance imaging vs. high-fidelity catheterization in experimental pulmonary hypertension.
Academic Article A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth.
Academic Article A central role for CD68(+) macrophages in hepatopulmonary syndrome. Reversal by macrophage depletion.
Academic Article Phosphodiesterase type 5 is highly expressed in the hypertrophied human right ventricle, and acute inhibition of phosphodiesterase type 5 improves contractility.
Academic Article Hydroxylamine is a vasorelaxant and a possible intermediate in the oxidative conversion of L-arginine to nitric oxide.
Academic Article Antenatal sildenafil treatment attenuates pulmonary hypertension in experimental congenital diaphragmatic hernia.
Academic Article Rodent models of pulmonary hypertension: harmonisation with the world health organisation's categorisation of human PH.
Academic Article Oxygen radicals and antioxidant enzymes alter pulmonary vascular reactivity in the rat lung.
Academic Article Therapeutic inhibition of fatty acid oxidation in right ventricular hypertrophy: exploiting Randle's cycle.
Academic Article Lung ยน8F-fluorodeoxyglucose positron emission tomography for diagnosis and monitoring of pulmonary arterial hypertension.
Academic Article Hypoxic pulmonary vasoconstriction is unaltered by creatine depletion induced by dietary beta-guanidino propionic acid.
Academic Article Gene therapy targeting survivin selectively induces pulmonary vascular apoptosis and reverses pulmonary arterial hypertension.
Academic Article Chronic EDRF inhibition and hypoxia: effects on pulmonary circulation and systemic blood pressure.
Academic Article Hypoxic pulmonary vasoconstriction is enhanced by inhibition of the synthesis of an endothelium derived relaxing factor.
Academic Article Airway delivery of mesenchymal stem cells prevents arrested alveolar growth in neonatal lung injury in rats.
Academic Article Epigenetic attenuation of mitochondrial superoxide dismutase 2 in pulmonary arterial hypertension: a basis for excessive cell proliferation and a new therapeutic target.
Academic Article The membrane protein MiRP3 regulates Kv4.2 channels in a KChIP-dependent manner.
Academic Article Dynamin-related protein 1-mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary hypertension.
Academic Article Comparison of the hemodynamic effects of nitric oxide and endothelium-dependent vasodilators in intact lungs.
Academic Article Increased endothelium-derived NO in hypertensive pulmonary circulation of chronically hypoxic rats.
Academic Article Nitric oxide and cGMP cause vasorelaxation by activation of a charybdotoxin-sensitive K channel by cGMP-dependent protein kinase.
Academic Article Effect of graded hypoxia on the induction and function of inducible nitric oxide synthase in rat mesangial cells.
Academic Article Dithionite increases radical formation and decreases vasoconstriction in the lung. Evidence that dithionite does not mimic alveolar hypoxia.
Academic Article Diphenyleneiodonium inhibits both potassium and calcium currents in isolated pulmonary artery smooth muscle cells.
Academic Article Effects of dietary fish oil on lung phospholipid fatty acid composition and intrinsic pulmonary vascular reactivity.
Academic Article Statin therapy, alone or with rapamycin, does not reverse monocrotaline pulmonary arterial hypertension: the rapamcyin-atorvastatin-simvastatin study.
Academic Article A redox-based O2 sensor in rat pulmonary vasculature.
Academic Article Chronic hypoxic pulmonary hypertension. Is thrombin involved?
Academic Article Simultaneous measurement of O2 radicals and pulmonary vascular reactivity in rat lung.
Academic Article Effect of dietary fish oil on lung lipid profile and hypoxic pulmonary hypertension.
Academic Article Anorexic agents aminorex, fenfluramine, and dexfenfluramine inhibit potassium current in rat pulmonary vascular smooth muscle and cause pulmonary vasoconstriction.
Academic Article NG-monomethyl-L-arginine causes nitric oxide synthesis in isolated arterial rings: trouble in paradise.
Academic Article A role for potassium channels in smooth muscle cells and platelets in the etiology of primary pulmonary hypertension.
Academic Article Potassium channels regulate tone in rat pulmonary veins.
Academic Article Diversity in mitochondrial function explains differences in vascular oxygen sensing.
Academic Article Pulmonary arterial hypertension: future directions: report of a National Heart, Lung and Blood Institute/Office of Rare Diseases workshop.
Academic Article Pergolide is an inhibitor of voltage-gated potassium channels, including Kv1.5, and causes pulmonary vasoconstriction.
Academic Article Mitochondrial metabolism, redox signaling, and fusion: a mitochondria-ROS-HIF-1alpha-Kv1.5 O2-sensing pathway at the intersection of pulmonary hypertension and cancer.
Academic Article Pathways of proliferation: new targets to inhibit the growth of vascular smooth muscle cells.
Academic Article A proposed mitochondrial-metabolic mechanism for initiation and maintenance of pulmonary arterial hypertension in fawn-hooded rats: the Warburg model of pulmonary arterial hypertension.
Academic Article H2O2 injury causes Ca(2+)-dependent and -independent hydrolysis of phosphatidylcholine in alveolar epithelial cells.
Academic Article PGC1a-mediated mitofusin-2 deficiency in female rats and humans with pulmonary arterial hypertension.
Academic Article FOXO1-mediated upregulation of pyruvate dehydrogenase kinase-4 (PDK4) decreases glucose oxidation and impairs right ventricular function in pulmonary hypertension: therapeutic benefits of dichloroacetate.
Academic Article GRK2-mediated inhibition of adrenergic and dopaminergic signaling in right ventricular hypertrophy: therapeutic implications in pulmonary hypertension.
Academic Article Cardiac glutaminolysis: a maladaptive cancer metabolism pathway in the right ventricle in pulmonary hypertension.
Academic Article Ischemia-induced Drp1 and Fis1-mediated mitochondrial fission and right ventricular dysfunction in pulmonary hypertension.
Academic Article Transcriptomic Signature of Right Ventricular Failure in Experimental Pulmonary Arterial Hypertension: Deep Sequencing Demonstrates Mitochondrial, Fibrotic, Inflammatory and Angiogenic Abnormalities.
Academic Article Epigenetic Dysregulation of the Dynamin-Related Protein 1 Binding Partners MiD49 and MiD51 Increases Mitotic Mitochondrial Fission and Promotes Pulmonary Arterial Hypertension: Mechanistic and Therapeutic Implications.
Academic Article Rodent models of group 1 pulmonary hypertension.
Academic Article Emerging concepts in the molecular basis of pulmonary arterial hypertension: part I: metabolic plasticity and mitochondrial dynamics in the pulmonary circulation and right ventricle in pulmonary arterial hypertension.
Academic Article Colchicine Depolymerizes Microtubules, Increases Junctophilin-2, and Improves Right Ventricular Function in Experimental Pulmonary Arterial Hypertension.
Academic Article MicroRNA-138 and MicroRNA-25 Down-regulate Mitochondrial Calcium Uniporter, Causing the Pulmonary Arterial Hypertension Cancer Phenotype.
Academic Article Ndufs2, a Core Subunit of Mitochondrial Complex I, Is Essential for Acute Oxygen-Sensing and Hypoxic Pulmonary Vasoconstriction.
Academic Article Left Atrial Stenosis Induced Pulmonary Venous Arterialization and Group 2 Pulmonary Hypertension in Rat.
Academic Article Metabolic Syndrome Exacerbates Pulmonary Hypertension due to Left Heart Disease.
Academic Article Identification of novel dynamin-related protein 1 (Drp1) GTPase inhibitors: Therapeutic potential of Drpitor1 and Drpitor1a in cancer and cardiac ischemia-reperfusion injury.
Academic Article Epigenetic Metabolic Reprogramming of Right Ventricular Fibroblasts in Pulmonary Arterial Hypertension: A Pyruvate Dehydrogenase Kinase-Dependent Shift in Mitochondrial Metabolism Promotes Right Ventricular Fibrosis.
Academic Article Supra-coronary aortic banding improves right ventricular function in experimental pulmonary arterial hypertension in rats by increasing systolic right coronary artery perfusion.
Academic Article Identification of Long Noncoding RNA H19 as a New Biomarker and Therapeutic Target in Right Ventricular Failure in Pulmonary Arterial Hypertension.
Academic Article Excess Protein O-GlcNAcylation Links Metabolic Derangements to Right Ventricular Dysfunction in Pulmonary Arterial Hypertension.
Academic Article Inflammatory Glycoprotein 130 Signaling Links Changes in Microtubules and Junctophilin-2 to Altered Mitochondrial Metabolism and Right Ventricular Contractility.
Academic Article Inhibiting pyruvate kinase muscle isoform 2 regresses group 2 pulmonary hypertension induced by supra-coronary aortic banding.
Academic Article Macrophage-NLRP3 Activation Promotes Right Ventricle Failure in Pulmonary Arterial Hypertension.
Academic Article An integrated proteomic and transcriptomic signature of the failing right ventricle in monocrotaline induced pulmonary arterial hypertension in male rats.
Grant Impaired mitochondrial fusion in pulmonary arterial hypertension
Grant EDRF IN NORMAL AND HYPERTENSIVE PULMONARY VASCULATURE
Academic Article Multi-omic and multispecies analysis of right ventricular dysfunction.
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  • Rats