 Interferons
"Interferons" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins secreted by vertebrate cells in response to a wide variety of inducers. They confer resistance against many different viruses, inhibit proliferation of normal and malignant cells, impede multiplication of intracellular parasites, enhance macrophage and granulocyte phagocytosis, augment natural killer cell activity, and show several other immunomodulatory functions.
| Descriptor ID |
D007372
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| MeSH Number(s) |
D12.644.276.374.440 D12.644.276.718 D12.776.467.374.440 D12.776.467.718 D23.529.374.440 D23.529.718
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Interferons".
Below are MeSH descriptors whose meaning is more specific than "Interferons".
This graph shows the total number of publications written about "Interferons" by people in this website by year, and whether "Interferons" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1981 | 0 | 1 | 1 | | 1982 | 1 | 0 | 1 | | 1983 | 1 | 1 | 2 | | 1984 | 0 | 1 | 1 | | 1985 | 1 | 0 | 1 | | 1986 | 3 | 0 | 3 | | 1987 | 1 | 2 | 3 | | 1988 | 0 | 1 | 1 | | 1989 | 0 | 1 | 1 | | 1990 | 1 | 2 | 3 | | 1991 | 0 | 2 | 2 | | 1992 | 0 | 3 | 3 | | 1993 | 1 | 0 | 1 | | 1994 | 1 | 4 | 5 | | 1995 | 1 | 2 | 3 | | 1996 | 0 | 1 | 1 | | 1998 | 1 | 1 | 2 | | 1999 | 0 | 1 | 1 | | 2001 | 1 | 2 | 3 | | 2002 | 2 | 2 | 4 | | 2004 | 1 | 1 | 2 | | 2006 | 0 | 1 | 1 | | 2007 | 2 | 3 | 5 | | 2008 | 1 | 0 | 1 | | 2009 | 1 | 0 | 1 | | 2010 | 1 | 5 | 6 | | 2011 | 4 | 9 | 13 | | 2012 | 4 | 5 | 9 | | 2013 | 0 | 4 | 4 | | 2014 | 2 | 3 | 5 | | 2015 | 3 | 1 | 4 | | 2016 | 1 | 1 | 2 | | 2017 | 2 | 0 | 2 | | 2019 | 0 | 1 | 1 | | 2020 | 1 | 1 | 2 | | 2021 | 1 | 1 | 2 | | 2022 | 0 | 2 | 2 |
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Below are the most recent publications written about "Interferons" by people in Profiles.
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Nguyen LC, Yang D, Nicolaescu V, Best TJ, Gula H, Saxena D, Gabbard JD, Chen SN, Ohtsuki T, Friesen JB, Drayman N, Mohamed A, Dann C, Silva D, Robinson-Mailman L, Valdespino A, Stock L, Suárez E, Jones KA, Azizi SA, Demarco JK, Severson WE, Anderson CD, Millis JM, Dickinson BC, Tay S, Oakes SA, Pauli GF, Palmer KE. Cannabidiol inhibits SARS-CoV-2 replication through induction of the host ER stress and innate immune responses. Sci Adv. 2022 Feb 25; 8(8):eabi6110.
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Hou Y, Zhou Y, Jehi L, Luo Y, Gack MU, Chan TA, Yu H, Eng C, Pieper AA, Cheng F. Aging-related cell type-specific pathophysiologic immune responses that exacerbate disease severity in aged COVID-19 patients. Aging Cell. 2022 02; 21(2):e13544.
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Huang S, Zhang W, Katanski CD, Dersh D, Dai Q, Lolans K, Yewdell J, Eren AM, Pan T. Interferon inducible pseudouridine modification in human mRNA by quantitative nanopore profiling. Genome Biol. 2021 12 06; 22(1):330.
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Sayaman RW, Saad M, Thorsson V, Hu D, Hendrickx W, Roelands J, Porta-Pardo E, Mokrab Y, Farshidfar F, Kirchhoff T, Sweis RF, Bathe OF, Heimann C, Campbell MJ, Stretch C, Huntsman S, Graff RE, Syed N, Radvanyi L, Shelley S, Wolf D, Marincola FM, Ceccarelli M, Galon J, Ziv E, Bedognetti D. Germline genetic contribution to the immune landscape of cancer. Immunity. 2021 02 09; 54(2):367-386.e8.
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James JA, Guthridge JM, Chen H, Lu R, Bourn RL, Bean K, Munroe ME, Smith M, Chakravarty E, Baer AN, Noaiseh G, Parke A, Boyle K, Keyes-Elstein L, Coca A, Utset T, Genovese MC, Pascual V, Utz PJ, Holers VM, Deane KD, Sivils KL, Aberle T, Wallace DJ, McNamara J, Franchimont N, St Clair EW. Unique Sjögren's syndrome patient subsets defined by molecular features. Rheumatology (Oxford). 2020 04 01; 59(4):860-868.
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Metz PJ, Ching KA, Xie T, Delgado Cuenca P, Niessen S, Tatlock JH, Jensen-Pergakes K, Murray BW. Symmetric Arginine Dimethylation Is Selectively Required for mRNA Splicing and the Initiation of Type I and Type III Interferon Signaling. Cell Rep. 2020 02 11; 30(6):1935-1950.e8.
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Poklepovic AS, Luke JJ. Considering adjuvant therapy for stage II melanoma. Cancer. 2020 03 15; 126(6):1166-1174.
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Furlong K, Hwang S. Autophagy and Noroviruses. Viruses. 2019 03 12; 11(3).
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Brown HM, Biering SB, Zhu A, Choi J, Hwang S. Demarcation of Viral Shelters Results in Destruction by Membranolytic GTPases: Antiviral Function of Autophagy Proteins and Interferon-Inducible GTPases. Bioessays. 2018 06; 40(6):e1700231.
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Walter KR, Goodman ML, Singhal H, Hall JA, Li T, Holloran SM, Trinca GM, Gibson KA, Jin VX, Greene GL, Hagan CR. Interferon-Stimulated Genes Are Transcriptionally Repressed by PR in Breast Cancer. Mol Cancer Res. 2017 10; 15(10):1331-1340.
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