 Methyltransferases
"Methyltransferases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subclass of enzymes of the transferase class that catalyze the transfer of a methyl group from one compound to another. (Dorland, 28th ed) EC 2.1.1.
| Descriptor ID |
D008780
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| MeSH Number(s) |
D08.811.913.555.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Methyltransferases".
Below are MeSH descriptors whose meaning is more specific than "Methyltransferases".
This graph shows the total number of publications written about "Methyltransferases" by people in this website by year, and whether "Methyltransferases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1981 | 1 | 0 | 1 | | 1984 | 3 | 0 | 3 | | 1985 | 5 | 1 | 6 | | 1986 | 1 | 0 | 1 | | 1987 | 2 | 0 | 2 | | 1988 | 6 | 2 | 8 | | 1989 | 3 | 1 | 4 | | 1990 | 5 | 0 | 5 | | 1991 | 4 | 1 | 5 | | 1992 | 1 | 1 | 2 | | 1993 | 6 | 2 | 8 | | 1994 | 3 | 2 | 5 | | 1995 | 3 | 1 | 4 | | 1996 | 2 | 0 | 2 | | 1998 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 | | 2000 | 0 | 1 | 1 | | 2001 | 1 | 1 | 2 | | 2002 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 | | 2006 | 2 | 1 | 3 | | 2008 | 2 | 2 | 4 | | 2009 | 0 | 1 | 1 | | 2010 | 0 | 2 | 2 | | 2011 | 1 | 1 | 2 | | 2013 | 3 | 1 | 4 | | 2014 | 3 | 3 | 6 | | 2015 | 2 | 2 | 4 | | 2016 | 1 | 0 | 1 | | 2017 | 0 | 1 | 1 | | 2018 | 2 | 5 | 7 | | 2019 | 4 | 2 | 6 | | 2020 | 8 | 2 | 10 | | 2021 | 4 | 5 | 9 | | 2022 | 1 | 1 | 2 |
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Below are the most recent publications written about "Methyltransferases" by people in Profiles.
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Daniel LL, Dickson AL, Zanussi JT, Miller-Fleming TW, Straub PS, Wei WQ, Plummer WD, Dupont WD, Liu G, Anandi P, Reese TS, Birdwell KA, Kawai VK, Hung AM, Cox NJ, Feng Q, Stein CM, Chung CP. Predicted expression of genes involved in the thiopurine metabolic pathway and azathioprine discontinuation due to myelotoxicity. Clin Transl Sci. 2022 04; 15(4):859-865.
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Sepich-Poore C, Zheng Z, Schmitt E, Wen K, Zhang ZS, Cui XL, Dai Q, Zhu AC, Zhang L, Sanchez Castillo A, Tan H, Peng J, Zhuang X, He C, Nachtergaele S. The METTL5-TRMT112 N6-methyladenosine methyltransferase complex regulates mRNA translation via 18S rRNA methylation. J Biol Chem. 2022 03; 298(3):101590.
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Wei J, Harada BT, Lu D, Ma R, Gao B, Xu Y, Montauti E, Mani N, Chaudhuri SM, Gregory S, Weinberg SE, Zhang DD, Green R, He C, Fang D. HRD1-mediated METTL14 degradation regulates m6A mRNA modification to suppress ER proteotoxic liver disease. Mol Cell. 2021 12 16; 81(24):5052-5065.e6.
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Dickson AL, Daniel LL, Zanussi J, Dale Plummer W, Wei WQ, Liu G, Reese T, Anandi P, Birdwell KA, Kawai V, Cox NJ, Dupont WD, Hung AM, Feng Q, Stein CM, Chung CP. TPMT and NUDT15 Variants Predict Discontinuation of Azathioprine for Myelotoxicity in Patients with Inflammatory Disease: Real-World Clinical Results. Clin Pharmacol Ther. 2022 01; 111(1):263-271.
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Yang Z, Yang S, Cui YH, Wei J, Shah P, Park G, Cui X, He C, He YY. METTL14 facilitates global genome repair and suppresses skin tumorigenesis. Proc Natl Acad Sci U S A. 2021 08 31; 118(35).
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Wilamowski M, Sherrell DA, Minasov G, Kim Y, Shuvalova L, Lavens A, Chard R, Maltseva N, Jedrzejczak R, Rosas-Lemus M, Saint N, Foster IT, Michalska K, Satchell KJF, Joachimiak A. 2'-O methylation of RNA cap in SARS-CoV-2 captured by serial crystallography. Proc Natl Acad Sci U S A. 2021 05 25; 118(21).
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Samra N, Toubiana S, Yttervik H, Tzur-Gilat A, Morani I, Itzkovich C, Giladi L, Abu Jabal K, Cao JZ, Godley LA, Mory A, Baris Feldman H, Tveten K, Selig S, Weiss K. RBL2 bi-allelic truncating variants cause severe motor and cognitive impairment without evidence for abnormalities in DNA methylation or telomeric function. J Hum Genet. 2021 Nov; 66(11):1101-1112.
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Delgado DA, Chernoff M, Huang L, Tong L, Chen L, Jasmine F, Shinkle J, Cole SA, Haack K, Kent J, Umans J, Best LG, Nelson H, Griend DV, Graziano J, Kibriya MG, Navas-Acien A, Karagas MR, Ahsan H, Pierce BL. Rare, Protein-Altering Variants in AS3MT and Arsenic Metabolism Efficiency: A Multi-Population Association Study. Environ Health Perspect. 2021 04; 129(4):47007.
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Lee J, Wu Y, Harada BT, Li Y, Zhao J, He C, Ma Y, Wu X. N6 -methyladenosine modification of lncRNA Pvt1 governs epidermal stemness. EMBO J. 2021 04 15; 40(8):e106276.
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He PC, He C. m6 A RNA methylation: from mechanisms to therapeutic potential. EMBO J. 2021 02 01; 40(3):e105977.
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