"Methyltransferases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subclass of enzymes of the transferase class that catalyze the transfer of a methyl group from one compound to another. (Dorland, 28th ed) EC 2.1.1.
| Descriptor ID |
D008780
|
| MeSH Number(s) |
D08.811.913.555.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Methyltransferases".
Below are MeSH descriptors whose meaning is more specific than "Methyltransferases".
This graph shows the total number of publications written about "Methyltransferases" by people in this website by year, and whether "Methyltransferases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 3 | 1 | 4 |
| 1996 | 2 | 0 | 2 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 1 | 1 | 2 |
| 2002 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 2 | 1 | 3 |
| 2008 | 2 | 2 | 4 |
| 2009 | 0 | 1 | 1 |
| 2010 | 2 | 1 | 3 |
| 2011 | 1 | 2 | 3 |
| 2013 | 3 | 1 | 4 |
| 2014 | 3 | 3 | 6 |
| 2015 | 1 | 2 | 3 |
| 2016 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 2 | 5 | 7 |
| 2019 | 4 | 2 | 6 |
| 2020 | 9 | 2 | 11 |
| 2021 | 4 | 5 | 9 |
| 2022 | 2 | 2 | 4 |
| 2023 | 2 | 7 | 9 |
| 2024 | 3 | 4 | 7 |
| 2025 | 2 | 0 | 2 |
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Below are the most recent publications written about "Methyltransferases" by people in Profiles.
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Acetylation of METTL3: A negative regulator of m6A deposition on chromatin-associated regulatory RNAs. Mol Cell. 2025 Apr 03; 85(7):1251-1252.
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Divergent roles of m6A in orchestrating brown and white adipocyte transcriptomes and systemic metabolism. Nat Commun. 2025 Jan 09; 16(1):533.
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m6A mRNA methylation by METTL14 regulates early pancreatic cell differentiation. EMBO J. 2024 Nov; 43(22):5445-5468.
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m6A mRNA methylation in brown fat regulates systemic insulin sensitivity via an inter-organ prostaglandin signaling axis independent of UCP1. Cell Metab. 2024 Oct 01; 36(10):2207-2227.e9.
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IGF2BP3 promotes mRNA degradation through internal m7G modification. Nat Commun. 2024 Aug 28; 15(1):7421.
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m6A RNA methylation regulates mitochondrial function. Hum Mol Genet. 2024 05 18; 33(11):969-980.
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Small-molecule inhibition of the METTL3/METTL14 complex suppresses neuroblastoma tumor growth and promotes differentiation. Cell Rep. 2024 05 28; 43(5):114165.
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Chemical manipulation of m1A mediates its detection in human tRNA. RNA. 2024 04 16; 30(5):548-559.
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Allele-specific control of rodent and human lncRNA KMT2E-AS1 promotes hypoxic endothelial pathology in pulmonary hypertension. Sci Transl Med. 2024 01 10; 16(729):eadd2029.
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The Role of Clonal Hematopoiesis of Indeterminant Potential and DNA (Cytosine-5)-Methyltransferase Dysregulation in Pulmonary Arterial Hypertension and Other Cardiovascular Diseases. Cells. 2023 10 26; 12(21).