"von Willebrand Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A high-molecular-weight plasma protein, produced by endothelial cells and megakaryocytes, that is part of the factor VIII/von Willebrand factor complex. The von Willebrand factor has receptors for collagen, platelets, and ristocetin activity as well as the immunologically distinct antigenic determinants. It functions in adhesion of platelets to collagen and hemostatic plug formation. The prolonged bleeding time in VON WILLEBRAND DISEASES is due to the deficiency of this factor.
| Descriptor ID |
D014841
|
| MeSH Number(s) |
D12.776.124.125.920 D23.119.985
|
| Concept/Terms |
von Willebrand Factor- von Willebrand Factor
- Factor VIIIR-Ag
- Factor VIIIR Ag
- Factor VIIIR-RCo
- Factor VIIIR RCo
- Ristocetin-Willebrand Factor
- Ristocetin Willebrand Factor
- von Willebrand Protein
- Factor VIII-Related Antigen
- Factor VIII Related Antigen
- Ristocetin Cofactor
|
Below are MeSH descriptors whose meaning is more general than "von Willebrand Factor".
Below are MeSH descriptors whose meaning is more specific than "von Willebrand Factor".
This graph shows the total number of publications written about "von Willebrand Factor" by people in this website by year, and whether "von Willebrand Factor" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1996 | 0 | 1 | 1 |
| 1998 | 0 | 3 | 3 |
| 2001 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 0 | 3 | 3 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 2 | 3 | 5 |
| 2020 | 1 | 0 | 1 |
| 2021 | 2 | 1 | 3 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "von Willebrand Factor" by people in Profiles.
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Portosinusoidal Vascular Disorder: A Heretofore Unrecognized Manifestation of Sickle Cell Disease? Mod Pathol. 2024 Jan; 37(1):100351.
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Analysis of College of American Pathologists von Willebrand Factor Proficiency Testing Program. Semin Thromb Hemost. 2022 Sep; 48(6):690-699.
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Humanized von Willebrand factor reduces platelet sequestration in ex vivo and in vivo xenotransplant models. Xenotransplantation. 2021 11; 28(6):e12712.
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Role of von Willebrand Factor in COVID-19 Associated Coagulopathy. J Appl Lab Med. 2021 09 01; 6(5):1305-1315.
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Staphylococcus aureus vWF-binding protein triggers a strong interaction between clumping factor A and host vWF. Commun Biol. 2021 04 12; 4(1):453.
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Case Report: Peripheral Retinal Ischemia and Retinal Neovascularization in von Willebrand Disease. Optom Vis Sci. 2021 04 01; 98(4):418-424.
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The Expression of von Willebrand Factor-Binding Protein Determines Joint-Invading Capacity of Staphylococcus aureus, a Core Mechanism of Septic Arthritis. mBio. 2020 11 17; 11(6).
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von Willebrand factor D and EGF domains is an evolutionarily conserved and required feature of blastemas capable of multitissue appendage regeneration. Evol Dev. 2020 07; 22(4):297-311.
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Recruitment of CD103+ dendritic cells via tumor-targeted chemokine delivery enhances efficacy of checkpoint inhibitor immunotherapy. Sci Adv. 2019 12; 5(12):eaay1357.
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Staphylococcus aureus endocarditis: distinct mechanisms of bacterial adhesion to damaged and inflamed heart valves. Eur Heart J. 2019 10 14; 40(39):3248-3259.