 Interferon-gamma
"Interferon-gamma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The major interferon produced by mitogenically or antigenically stimulated LYMPHOCYTES. It is structurally different from TYPE I INTERFERON and its major activity is immunoregulation. It has been implicated in the expression of CLASS II HISTOCOMPATIBILITY ANTIGENS in cells that do not normally produce them, leading to AUTOIMMUNE DISEASES.
| Descriptor ID |
D007371
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| MeSH Number(s) |
D12.644.276.374.440.893 D12.644.276.374.480.350 D12.644.276.374.480.615.350 D12.644.276.718.550 D12.776.467.374.440.893 D12.776.467.374.480.350 D12.776.467.374.480.615.350 D12.776.467.718.550 D23.529.374.440.893 D23.529.374.480.350 D23.529.374.480.615.350 D23.529.718.550
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| Concept/Terms |
Interferon-gamma- Interferon-gamma
- Type II Interferon
- Interferon, Type II
- Interferon, gamma
- Interferon, Immune
- Immune Interferon
- gamma-Interferon
- Interferon Type II
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Below are MeSH descriptors whose meaning is more general than "Interferon-gamma".
Below are MeSH descriptors whose meaning is more specific than "Interferon-gamma".
This graph shows the total number of publications written about "Interferon-gamma" by people in this website by year, and whether "Interferon-gamma" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1986 | 1 | 1 | 2 | | 1987 | 3 | 3 | 6 | | 1988 | 5 | 3 | 8 | | 1989 | 5 | 4 | 9 | | 1990 | 3 | 3 | 6 | | 1991 | 2 | 3 | 5 | | 1992 | 3 | 4 | 7 | | 1993 | 3 | 6 | 9 | | 1994 | 3 | 4 | 7 | | 1995 | 7 | 4 | 11 | | 1996 | 3 | 4 | 7 | | 1997 | 3 | 6 | 9 | | 1998 | 7 | 5 | 12 | | 1999 | 3 | 8 | 11 | | 2000 | 4 | 3 | 7 | | 2001 | 7 | 6 | 13 | | 2002 | 3 | 10 | 13 | | 2003 | 4 | 6 | 10 | | 2004 | 5 | 14 | 19 | | 2005 | 4 | 7 | 11 | | 2006 | 4 | 11 | 15 | | 2007 | 5 | 11 | 16 | | 2008 | 8 | 9 | 17 | | 2009 | 1 | 9 | 10 | | 2010 | 1 | 9 | 10 | | 2011 | 8 | 8 | 16 | | 2012 | 3 | 11 | 14 | | 2013 | 1 | 8 | 9 | | 2014 | 3 | 9 | 12 | | 2015 | 2 | 4 | 6 | | 2016 | 1 | 6 | 7 | | 2017 | 1 | 4 | 5 | | 2018 | 1 | 2 | 3 |
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Below are the most recent publications written about "Interferon-gamma" by people in Profiles.
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Aue G, Sun C, Liu D, Park JH, Pittaluga S, Tian X, Lee E, Soto S, Valdez J, Maric I, Stetler-Stevenson M, Yuan C, Nakamura Y, Muranski P, Wiestner A. Activation of Th1 Immunity within the Tumor Microenvironment Is Associated with Clinical Response to Lenalidomide in Chronic Lymphocytic Leukemia. J Immunol. 2018 10 01; 201(7):1967-1974.
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Kane M, Deiss F, Chervonsky A, Golovkina TV. A Single Locus Controls Interferon Gamma-Independent Antiretroviral Neutralizing Antibody Responses. J Virol. 2018 08 15; 92(16).
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Reardon CA, Lingaraju A, Schoenfelt KQ, Zhou G, Cui C, Jacobs-El H, Babenko I, Hoofnagle A, Czyz D, Shuman H, Vaisar T, Becker L. Obesity and Insulin Resistance Promote Atherosclerosis through an IFN?-Regulated Macrophage Protein Network. Cell Rep. 2018 06 05; 23(10):3021-3030.
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Wu J, Zhang H, Shi X, Xiao X, Fan Y, Minze LJ, Wang J, Ghobrial RM, Xia J, Sciammas R, Li XC, Chen W. Ablation of Transcription Factor IRF4 Promotes Transplant Acceptance by Driving Allogenic CD4+ T Cell Dysfunction. Immunity. 2017 12 19; 47(6):1114-1128.e6.
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Ma K, Xiao A, Park SH, Glenn L, Jackson L, Barot T, Weaver JR, Taylor-Fishwick DA, Luci DK, Maloney DJ, Mirmira RG, Imai Y, Nadler JL. 12-Lipoxygenase Inhibitor Improves Functions of Cytokine-Treated Human Islets and Type 2 Diabetic Islets. J Clin Endocrinol Metab. 2017 08 01; 102(8):2789-2797.
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Moulin M, Alguacil J, Gu S, Mehtougui A, Adams EJ, Peyrottes S, Champagne E. V?9Vd2 T cell activation by strongly agonistic nucleotidic phosphoantigens. Cell Mol Life Sci. 2017 12; 74(23):4353-4367.
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Biering SB, Choi J, Halstrom RA, Brown HM, Beatty WL, Lee S, McCune BT, Dominici E, Williams LE, Orchard RC, Wilen CB, Yamamoto M, Coers J, Taylor GA, Hwang S. Viral Replication Complexes Are Targeted by LC3-Guided Interferon-Inducible GTPases. Cell Host Microbe. 2017 Jul 12; 22(1):74-85.e7.
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Kammertoens T, Friese C, Arina A, Idel C, Briesemeister D, Rothe M, Ivanov A, Szymborska A, Patone G, Kunz S, Sommermeyer D, Engels B, Leisegang M, Textor A, Fehling HJ, Fruttiger M, Lohoff M, Herrmann A, Yu H, Weichselbaum R, Uckert W, Hübner N, Gerhardt H, Beule D, Schreiber H, Blankenstein T. Tumour ischaemia by interferon-? resembles physiological blood vessel regression. Nature. 2017 05 04; 545(7652):98-102.
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Williams JB, Horton BL, Zheng Y, Duan Y, Powell JD, Gajewski TF. The EGR2 targets LAG-3 and 4-1BB describe and regulate dysfunctional antigen-specific CD8+ T cells in the tumor microenvironment. J Exp Med. 2017 02; 214(2):381-400.
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Shen L, Gao Y, Liu Y, Zhang B, Liu Q, Wu J, Fan L, Ou Q, Zhang W, Shao L. PD-1/PD-L pathway inhibits M.tb-specific CD4+ T-cell functions and phagocytosis of macrophages in active tuberculosis. Sci Rep. 2016 12 07; 6:38362.
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