 Interferon-gamma
"Interferon-gamma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The major interferon produced by mitogenically or antigenically stimulated LYMPHOCYTES. It is structurally different from TYPE I INTERFERON and its major activity is immunoregulation. It has been implicated in the expression of CLASS II HISTOCOMPATIBILITY ANTIGENS in cells that do not normally produce them, leading to AUTOIMMUNE DISEASES.
| Descriptor ID |
D007371
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| MeSH Number(s) |
D12.644.276.374.440.893 D12.644.276.374.480.350 D12.644.276.374.480.615.350 D12.644.276.718.550 D12.776.467.374.440.893 D12.776.467.374.480.350 D12.776.467.374.480.615.350 D12.776.467.718.550 D23.529.374.440.893 D23.529.374.480.350 D23.529.374.480.615.350 D23.529.718.550
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| Concept/Terms |
Interferon-gamma- Interferon-gamma
- Type II Interferon
- Interferon, Type II
- Interferon, gamma
- Interferon, Immune
- Immune Interferon
- gamma-Interferon
- Interferon Type II
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Below are MeSH descriptors whose meaning is more general than "Interferon-gamma".
Below are MeSH descriptors whose meaning is more specific than "Interferon-gamma".
This graph shows the total number of publications written about "Interferon-gamma" by people in this website by year, and whether "Interferon-gamma" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1986 | 1 | 1 | 2 | | 1987 | 3 | 3 | 6 | | 1988 | 5 | 3 | 8 | | 1989 | 5 | 4 | 9 | | 1990 | 3 | 3 | 6 | | 1991 | 2 | 3 | 5 | | 1992 | 3 | 4 | 7 | | 1993 | 3 | 6 | 9 | | 1994 | 3 | 4 | 7 | | 1995 | 6 | 4 | 10 | | 1996 | 2 | 4 | 6 | | 1997 | 2 | 6 | 8 | | 1998 | 6 | 5 | 11 | | 1999 | 2 | 8 | 10 | | 2000 | 3 | 3 | 6 | | 2001 | 7 | 6 | 13 | | 2002 | 3 | 10 | 13 | | 2003 | 4 | 8 | 12 | | 2004 | 7 | 15 | 22 | | 2005 | 3 | 8 | 11 | | 2006 | 2 | 12 | 14 | | 2007 | 5 | 10 | 15 | | 2008 | 8 | 9 | 17 | | 2009 | 1 | 10 | 11 | | 2010 | 1 | 10 | 11 | | 2011 | 7 | 9 | 16 | | 2012 | 3 | 12 | 15 | | 2013 | 1 | 8 | 9 | | 2014 | 2 | 9 | 11 | | 2015 | 2 | 5 | 7 | | 2016 | 1 | 5 | 6 | | 2017 | 1 | 4 | 5 | | 2018 | 1 | 4 | 5 | | 2019 | 1 | 5 | 6 | | 2020 | 3 | 5 | 8 |
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Below are the most recent publications written about "Interferon-gamma" by people in Profiles.
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Zheng W, Ranoa DRE, Huang X, Hou Y, Yang K, Poli EC, Beckett MA, Fu YX, Weichselbaum RR. RIG-I-Like Receptor LGP2 Is Required for Tumor Control by Radiotherapy. Cancer Res. 2020 12 15; 80(24):5633-5641.
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Harris KM, Horn SE, Grant ML, Lang H, Sani G, Jensen-Wachspress MA, Kankate VV, Datar A, Lazarski CA, Bollard CM, Keller MD. T-Cell Therapeutics Targeting Human Parainfluenza Virus 3 Are Broadly Epitope Specific and Are Cross Reactive With Human Parainfluenza Virus 1. Front Immunol. 2020; 11:575977.
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Grasso CS, Tsoi J, Onyshchenko M, Abril-Rodriguez G, Ross-Macdonald P, Wind-Rotolo M, Champhekar A, Medina E, Torrejon DY, Shin DS, Tran P, Kim YJ, Puig-Saus C, Campbell K, Vega-Crespo A, Quist M, Martignier C, Luke JJ, Wolchok JD, Johnson DB, Chmielowski B, Hodi FS, Bhatia S, Sharfman W, Urba WJ, Slingluff CL, Diab A, Haanen JBAG, Algarra SM, Pardoll DM, Anagnostou V, Topalian SL, Velculescu VE, Speiser DE, Kalbasi A, Ribas A. Conserved Interferon-? Signaling Drives Clinical Response to Immune Checkpoint Blockade Therapy in Melanoma. Cancer Cell. 2020 10 12; 38(4):500-515.e3.
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Choi JW, Withers SS, Chang H, Spanier JA, De La Trinidad VL, Panesar H, Fife BT, Sciammas R, Sparger EE, Moore PF, Kent MS, Rebhun RB, McSorley SJ. Development of canine PD-1/PD-L1 specific monoclonal antibodies and amplification of canine T cell function. PLoS One. 2020; 15(7):e0235518.
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Alegre ML. Liver Protection by ILC1s. Am J Transplant. 2020 05; 20(5):1215.
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Abadie V, Kim SM, Lejeune T, Palanski BA, Ernest JD, Tastet O, Voisine J, Discepolo V, Marietta EV, Hawash MBF, Ciszewski C, Bouziat R, Panigrahi K, Horwath I, Zurenski MA, Lawrence I, Dumaine A, Yotova V, Grenier JC, Murray JA, Khosla C, Barreiro LB, Jabri B. IL-15, gluten and HLA-DQ8 drive tissue destruction in coeliac disease. Nature. 2020 02; 578(7796):600-604.
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Williams JB, Li S, Higgs EF, Cabanov A, Wang X, Huang H, Gajewski TF. Tumor heterogeneity and clonal cooperation influence the immune selection of IFN-?-signaling mutant cancer cells. Nat Commun. 2020 01 30; 11(1):602.
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Nakayasu ES, Syed F, Tersey SA, Gritsenko MA, Mitchell HD, Chan CY, Dirice E, Turatsinze JV, Cui Y, Kulkarni RN, Eizirik DL, Qian WJ, Webb-Robertson BM, Evans-Molina C, Mirmira RG, Metz TO. Comprehensive Proteomics Analysis of Stressed Human Islets Identifies GDF15 as a Target for Type 1 Diabetes Intervention. Cell Metab. 2020 02 04; 31(2):363-374.e6.
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Kelly RJ, Lee J, Bang YJ, Almhanna K, Blum-Murphy M, Catenacci DVT, Chung HC, Wainberg ZA, Gibson MK, Lee KW, Bendell JC, Denlinger CS, Chee CE, Omori T, Leidner R, Lenz HJ, Chao Y, Rebelatto MC, Brohawn PZ, He P, McDevitt J, Sheth S, Englert JM, Ku GY. Safety and Efficacy of Durvalumab and Tremelimumab Alone or in Combination in Patients with Advanced Gastric and Gastroesophageal Junction Adenocarcinoma. Clin Cancer Res. 2020 02 15; 26(4):846-854.
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Huang R, Wu J, Zhou X, Jiang H, Guoying Zhou G, Roizman B. Herpes Simplex Virus 1 MicroRNA miR-H28 Exported to Uninfected Cells in Exosomes Restricts Cell-to-Cell Virus Spread by Inducing Gamma Interferon mRNA. J Virol. 2019 11 01; 93(21).
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