 Gene Rearrangement, B-Lymphocyte
"Gene Rearrangement, B-Lymphocyte" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Ordered rearrangement of B-lymphocyte variable gene regions coding for the IMMUNOGLOBULIN CHAINS, thereby contributing to antibody diversity. It occurs during the differentiation of the IMMATURE B-LYMPHOCYTES.
| Descriptor ID |
D015322
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| MeSH Number(s) |
G05.355.330.401 G12.425.742.500 G12.500.349.500
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| Concept/Terms |
Gene Rearrangement, B-Lymphocyte- Gene Rearrangement, B-Lymphocyte
- Gene Rearrangement, B Lymphocyte
- B-Lymphocyte Gene Rearrangement
- B Lymphocyte Gene Rearrangement
- B-Lymphocyte Gene Rearrangements
- Gene Rearrangements, B-Lymphocyte
- Rearrangement, B-Lymphocyte Gene
- Rearrangements, B-Lymphocyte Gene
- Gene Rearrangement, B-Cell
- B-Cell Gene Rearrangements
- Gene Rearrangement, B Cell
- Gene Rearrangements, B-Cell
- Rearrangement, B-Cell Gene
- Rearrangements, B-Cell Gene
- B-Cell Gene Rearrangement
- B Cell Gene Rearrangement
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Below are MeSH descriptors whose meaning is more general than "Gene Rearrangement, B-Lymphocyte".
Below are MeSH descriptors whose meaning is more specific than "Gene Rearrangement, B-Lymphocyte".
This graph shows the total number of publications written about "Gene Rearrangement, B-Lymphocyte" by people in this website by year, and whether "Gene Rearrangement, B-Lymphocyte" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1988 | 1 | 0 | 1 | | 1989 | 1 | 1 | 2 | | 1990 | 0 | 2 | 2 | | 1991 | 0 | 1 | 1 | | 1992 | 1 | 0 | 1 | | 1993 | 1 | 2 | 3 | | 1994 | 0 | 1 | 1 | | 1995 | 1 | 0 | 1 | | 1997 | 4 | 0 | 4 | | 1999 | 2 | 1 | 3 | | 2000 | 2 | 1 | 3 | | 2003 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2005 | 2 | 0 | 2 | | 2006 | 2 | 1 | 3 | | 2008 | 1 | 0 | 1 | | 2009 | 2 | 0 | 2 | | 2011 | 1 | 0 | 1 | | 2012 | 0 | 1 | 1 | | 2013 | 1 | 0 | 1 | | 2015 | 1 | 1 | 2 |
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Below are the most recent publications written about "Gene Rearrangement, B-Lymphocyte" by people in Profiles.
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Henry Dunand CJ, Wilson PC. Restricted, canonical, stereotyped and convergent immunoglobulin responses. Philos Trans R Soc Lond B Biol Sci. 2015 Sep 05; 370(1676).
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Childs LM, Baskerville EB, Cobey S. Trade-offs in antibody repertoires to complex antigens. Philos Trans R Soc Lond B Biol Sci. 2015 Sep 05; 370(1676).
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Johnson RC, Ma L, Cherry AM, Arber DA, George TI. B-cell transcription factor expression and immunoglobulin gene rearrangement frequency in acute myeloid leukemia with t(8;21)(q22;q22). Am J Clin Pathol. 2013 Sep; 140(3):355-62.
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Nakagawa R, Vukovic M, Cosimo E, Michie AM. Modulation of PKC-a promotes lineage reprogramming of committed B lymphocytes. Eur J Immunol. 2012 Apr; 42(4):1005-15.
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Kalinina O, Doyle-Cooper CM, Miksanek J, Meng W, Prak EL, Weigert MG. Alternative mechanisms of receptor editing in autoreactive B cells. Proc Natl Acad Sci U S A. 2011 Apr 26; 108(17):7125-30.
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Chen W, Lau SK, Fong D, Wang J, Wang E, Arber DA, Weiss LM, Huang Q. High frequency of clonal immunoglobulin receptor gene rearrangements in sporadic histiocytic/dendritic cell sarcomas. Am J Surg Pathol. 2009 Jun; 33(6):863-73.
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Johnson K, Reddy KL, Singh H. Molecular pathways and mechanisms regulating the recombination of immunoglobulin genes during B-lymphocyte development. Adv Exp Med Biol. 2009; 650:133-47.
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Khan SN, Witsch EJ, Goodman NG, Panigrahi AK, Chen C, Jiang Y, Cline AM, Erikson J, Weigert M, Prak ET, Radic M. Editing and escape from editing in anti-DNA B cells. Proc Natl Acad Sci U S A. 2008 Mar 11; 105(10):3861-6.
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Tan BT, Warnke RA, Arber DA. The frequency of B- and T-cell gene rearrangements and epstein-barr virus in T-cell lymphomas: a comparison between angioimmunoblastic T-cell lymphoma and peripheral T-cell lymphoma, unspecified with and without associated B-cell proliferations. J Mol Diagn. 2006 Sep; 8(4):466-75; quiz 527.
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Sekiguchi DR, Yunk L, Gary D, Charan D, Srivastava B, Allman D, Weigert MG, Prak ET. Development and selection of edited B cells in B6.56R mice. J Immunol. 2006 Jun 01; 176(11):6879-87.
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