"Genes, ras" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Family of retrovirus-associated DNA sequences (ras) originally isolated from Harvey (H-ras, Ha-ras, rasH) and Kirsten (K-ras, Ki-ras, rasK) murine sarcoma viruses. Ras genes are widely conserved among animal species and sequences corresponding to both H-ras and K-ras genes have been detected in human, avian, murine, and non-vertebrate genomes. The closely related N-ras gene has been detected in human neuroblastoma and sarcoma cell lines. All genes of the family have a similar exon-intron structure and each encodes a p21 protein.
Descriptor ID |
D011905
|
MeSH Number(s) |
G05.360.340.024.340.375.500.791.550
|
Concept/Terms |
N-ras Genes- N-ras Genes
- Genes, N-ras
- N ras Genes
- N-ras Gene
- N-ras Oncogenes
- N ras Oncogenes
- N-ras Oncogene
v-Ha-ras Genes- v-Ha-ras Genes
- Gene, v-Ha-ras
- Genes, v-Ha-ras
- v Ha ras Genes
- v-Ha-ras Gene
v-Ki-ras Genes- v-Ki-ras Genes
- Gene, v-Ki-ras
- Genes, v-Ki-ras
- v Ki ras Genes
- v-Ki-ras Gene
Ha-ras Genes- Ha-ras Genes
- Gene, Ha-ras
- Genes, Ha-ras
- Ha ras Genes
- Ha-ras Gene
Ki-ras Genes- Ki-ras Genes
- Gene, Ki-ras
- Genes, Ki-ras
- Ki ras Genes
- Ki-ras Gene
|
Below are MeSH descriptors whose meaning is more general than "Genes, ras".
Below are MeSH descriptors whose meaning is more specific than "Genes, ras".
This graph shows the total number of publications written about "Genes, ras" by people in this website by year, and whether "Genes, ras" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1994 | 4 | 2 | 6 |
1995 | 2 | 0 | 2 |
1996 | 2 | 2 | 4 |
1997 | 2 | 1 | 3 |
1998 | 0 | 1 | 1 |
1999 | 0 | 1 | 1 |
2000 | 0 | 1 | 1 |
2001 | 0 | 1 | 1 |
2002 | 1 | 0 | 1 |
2003 | 1 | 0 | 1 |
2004 | 1 | 0 | 1 |
2005 | 0 | 1 | 1 |
2006 | 0 | 3 | 3 |
2007 | 0 | 1 | 1 |
2008 | 2 | 0 | 2 |
2009 | 1 | 1 | 2 |
2010 | 1 | 1 | 2 |
2011 | 1 | 4 | 5 |
2012 | 2 | 0 | 2 |
2013 | 1 | 1 | 2 |
2015 | 2 | 1 | 3 |
2016 | 1 | 0 | 1 |
2017 | 0 | 2 | 2 |
2018 | 1 | 0 | 1 |
2019 | 1 | 0 | 1 |
2023 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Genes, ras" by people in Profiles.
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New insights into RAS in head and neck cancer. Biochim Biophys Acta Rev Cancer. 2023 11; 1878(6):188963.
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Oral MEK 1/2 Inhibitor Trametinib in Combination With AKT Inhibitor GSK2141795 in Patients With Acute Myeloid Leukemia With RAS Mutations: A Phase II Study. Clin Lymphoma Myeloma Leuk. 2019 07; 19(7):431-440.e13.
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Ras and the Plasma Membrane: A Complicated Relationship. Cold Spring Harb Perspect Med. 2018 10 01; 8(10).
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Effect of First-Line Chemotherapy Combined With Cetuximab or Bevacizumab on Overall Survival in Patients With KRAS Wild-Type Advanced or Metastatic Colorectal Cancer: A Randomized Clinical Trial. JAMA. 2017 06 20; 317(23):2392-2401.
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Clear Cell Change in Thyroid Carcinoma: A Clinicopathologic and Molecular Study with Identification of Variable Genetic Anomalies. Thyroid. 2017 06; 27(6):819-824.
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Oncogenic K-Ras Binds to an Anionic Membrane in Two Distinct Orientations: A Molecular Dynamics Analysis. Biophys J. 2016 Mar 08; 110(5):1125-38.
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Extended RAS Gene Mutation Testing in Metastatic Colorectal Carcinoma to Predict Response to Anti-Epidermal Growth Factor Receptor Monoclonal Antibody Therapy: American Society of Clinical Oncology Provisional Clinical Opinion Update 2015 Summary. J Oncol Pract. 2016 Feb; 12(2):180-1.
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Extended RAS Gene Mutation Testing in Metastatic Colorectal Carcinoma to Predict Response to Anti-Epidermal Growth Factor Receptor Monoclonal Antibody Therapy: American Society of Clinical Oncology Provisional Clinical Opinion Update 2015. J Clin Oncol. 2016 Jan 10; 34(2):179-85.
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A Genetic Porcine Model of Cancer. PLoS One. 2015; 10(7):e0128864.
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Phase II study of the oral MEK inhibitor selumetinib in advanced acute myelogenous leukemia: a University of Chicago phase II consortium trial. Clin Cancer Res. 2014 Jan 15; 20(2):490-8.