Genes related to the erbA DNA sequence that was first isolated from the avian erythroblastosis virus (ERYTHROBLASTOSIS VIRUS, AVIAN), v-erbA. In cells, erbA genes encode thyroid hormone receptors (RECEPTORS, THYROID HORMONE). Two distinct c-erbA genes have been identified: erbA-alpha located at 17q21; and erbA-beta located at 3p24. Truncations at the N- and C-terminals of erbA result in products resembling v-erbA. Truncations affect hormone responsiveness but not DNA binding capacity.

Descriptor ID	D018776
MeSH Number(s)	G05.360.340.024.340.375.500.791.290
Concept/Terms	Genes, erbA Genes, erbA erbA Gene erbA Genes Genes, erbA-beta Genes, erbA-beta erbA-beta Gene erbA-beta Genes Genes, THRB Gene, THRB THRB Gene THRB Genes Genes, TR-beta TR-beta Gene TR-beta Genes Genes, erbA beta beta Gene, erbA beta Genes, erbA erbA beta Gene erbA beta Genes Genes, TR beta TR beta Gene TR beta Genes beta Gene, TR beta Genes, TR Genes, erbA-alpha Genes, erbA-alpha erbA-alpha Gene erbA-alpha Genes Genes, THRA Gene, THRA THRA Gene THRA Genes Genes, TR-alpha TR-alpha Gene TR-alpha Genes Genes, erbA alpha alpha Gene, erbA alpha Genes, erbA erbA alpha Gene erbA alpha Genes Genes, TR alpha TR alpha Gene TR alpha Genes alpha Gene, TR alpha Genes, TR v-erbA Genes v-erbA Genes v erbA Genes v-erbA Gene v-erbA Oncogenes v erbA Oncogenes v-erbA Oncogene c-erbA Genes c-erbA Genes c erbA Genes c-erbA Gene c-erbA Proto-Oncogenes c erbA Proto Oncogenes c-erbA Proto-Oncogene

Below are MeSH descriptors whose meaning is more general than "Genes, erbA".

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