"Genes, myb" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Retrovirus-associated DNA sequences (v-myb) originally isolated from the avian myeloblastosis and E26 leukemia viruses. The proto-oncogene c-myb codes for a nuclear protein involved in transcriptional regulation and appears to be essential for hematopoietic cell proliferation. The human myb gene is located at 6q22-23 on the short arm of chromosome 6. This is the point of break in translocations involved in T-cell acute lymphatic leukemia and in some ovarian cancers and melanomas. (From Ibelgaufts, Dictionary of Cytokines, 1995).
| Descriptor ID |
D020570
|
| MeSH Number(s) |
G05.360.340.024.340.375.500.791.418
|
| Concept/Terms |
v-myb Genes- v-myb Genes
- Gene, v-myb
- Genes, v-myb
- v myb Genes
- v-myb Gene
- myb Oncogene
- Oncogene, myb
- Oncogenes, myb
- myb Oncogenes
- v-myb Oncogenes
- Oncogene, v-myb
- Oncogenes, v-myb
- v myb Oncogenes
- v-myb Oncogene
c-myb Genes- c-myb Genes
- Gene, c-myb
- Genes, c-myb
- c myb Genes
- c-myb Gene
- c-myb Proto-Oncogenes
- Proto-Oncogene, c-myb
- Proto-Oncogenes, c-myb
- c myb Proto Oncogenes
- c-myb Proto-Oncogene
|
Below are MeSH descriptors whose meaning is more general than "Genes, myb".
Below are MeSH descriptors whose meaning is more specific than "Genes, myb".
This graph shows the total number of publications written about "Genes, myb" by people in this website by year, and whether "Genes, myb" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 1 | 2 |
| 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "Genes, myb" by people in Profiles.
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Role of c-Myb in the survival of pre B-cell acute lymphoblastic leukemia and leukemogenesis. Am J Hematol. 2012 Oct; 87(10):969-76.
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Drosophila myb exerts opposing effects on S phase, promoting proliferation and suppressing endoreduplication. Development. 2002 Oct; 129(19):4497-507.
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Activation of the nuclear transcription factor kappaB (NFkappaB) and differential gene expression in U87 glioma cells after exposure to the cytoprotector amifostine. Int J Radiat Oncol Biol Phys. 2002 May 01; 53(1):180-9.