The proto-oncogene product p120CBL and the adaptor proteins CRKL and c-CRK link c-ABL, p190BCR/ABL and p210BCR/ABL to the phosphatidylinositol-3' kinase pathway.
Sattler M, Salgia R, Okuda K, Uemura N, Durstin MA, Pisick E, Xu G, Li JL, Prasad KV, Griffin JD. The proto-oncogene product p120CBL and the adaptor proteins CRKL and c-CRK link c-ABL, p190BCR/ABL and p210BCR/ABL to the phosphatidylinositol-3' kinase pathway. Oncogene. 1996 Feb 15; 12(4):839-46.
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Adaptor Proteins, Signal Transducing
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Antibodies, Monoclonal
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Blotting, Western
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Cell Line
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Cell Line, Transformed
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Chromosomes, Human, Pair 21
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Chromosomes, Human, Pair 9
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Fusion Proteins, bcr-abl
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Humans
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Leukemia, Myelogenous, Chronic, BCR-ABL Positive
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Lymphocytes
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Nuclear Proteins
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Phosphatidylinositol 3-Kinases
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Phosphoproteins
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Phosphotransferases (Alcohol Group Acceptor)
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Precursor Cell Lymphoblastic Leukemia-Lymphoma
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Protein Binding
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Protein-Tyrosine Kinases
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Proto-Oncogene Proteins
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Proto-Oncogene Proteins c-abl
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Proto-Oncogene Proteins c-cbl
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Proto-Oncogene Proteins c-crk
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Translocation, Genetic
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Ubiquitin-Protein Ligases